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  1. Cathelicidins (CATHs) play an important role in the innate immune response against microbial infections. Among the four chicken cathelicidins, CATH-B1 is studied the least. In this study, the effect of CATH-B1...

    Authors: Lianci Peng, Maaike R. Scheenstra, Roel M. van Harten, Henk P. Haagsman and Edwin J. A. Veldhuizen

    Citation: Veterinary Research 2020 51:122

    Content type: Research article

    Published on:

  2. M. bovis is one of the leading causes of respiratory disease and antimicrobial use in cattle. The pathogen is widespread in different cattle industries worldwide, but highest prevalence is found in the veal indus...

    Authors: Jade Bokma, Nick Vereecke, Koen De Bleecker, Jozefien Callens, Stefaan Ribbens, Hans Nauwynck, Freddy Haesebrouck, Sebastiaan Theuns, Filip Boyen and Bart Pardon

    Citation: Veterinary Research 2020 51:121

    Content type: Research article

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  3. Bromodomain-containing protein 2 (BRD2) is a nucleus-localized serine-threonine kinase that plays pivotal roles in the transcriptional control of diverse genes. In our previous study, the chicken BRD2 (chBRD2)...

    Authors: Zhiqiang Duan, Yifan Han, Lei Zhou, Chao Yuan, Yanbi Wang, Caiqin Zhao, Hong Tang and Jiaqi Chen

    Citation: Veterinary Research 2020 51:120

    Content type: Research article

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  4. Lesions of adiaspiromycosis, a respiratory disease affecting wild animals, have been found mainly in dead mammals and free-living mammals captured for surveillance. No report has described an investigation of ...

    Authors: Asuka Takeshige, Mie Nakano, Daisuke Kondoh, Yuma Tanaka, Akio Sekiya, Takashi Yaguchi, Hidefumi Furuoka and Takahito Toyotome

    Citation: Veterinary Research 2020 51:119

    Content type: Research article

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  5. Cyclic GMP-AMP (cGAMP) synthase (cGAS) is an intracellular sensor of cytoplasmic viral DNA created during virus infection, which subsequently activates the stimulator of interferon gene (STING)-dependent type ...

    Authors: Zongyi Bo, Yurun Miao, Rui Xi, Qiuping Zhong, Chenyi Bao, Huan Chen, Liumei Sun, Yingjuan Qian, Yong-Sam Jung and Jianjun Dai

    Citation: Veterinary Research 2020 51:118

    Content type: Research article

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  6. In 2016/2017, H5N8 highly pathogenic avian influenza (HPAI) virus of the Goose/Guangdong lineage spread from Asia to Europe, causing the biggest and most widespread HPAI epidemic on record in wild and domestic...

    Authors: Valentina Caliendo, Lonneke Leijten, Lineke Begeman, Marjolein J. Poen, Ron A. M. Fouchier, Nancy Beerens and Thijs Kuiken

    Citation: Veterinary Research 2020 51:117

    Content type: Research article

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  7. Biomedical research relies on the use of animal models, and the animals used in those models receive medical care, including antibiotics for brief periods of time to treat conditions such as dermatitis, fight ...

    Authors: Scott W. Korte, Rebecca A. Dorfmeyer, Craig L. Franklin and Aaron C. Ericsson

    Citation: Veterinary Research 2020 51:116

    Content type: Research article

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  8. Coccidiosis, caused by Eimeria species parasites, has long been recognised as an economically significant disease of chickens. As the global chicken population continues to grow, and its contribution to food secu...

    Authors: Damer P. Blake, Jolene Knox, Ben Dehaeck, Ben Huntington, Thilak Rathinam, Venu Ravipati, Simeon Ayoade, Will Gilbert, Ayotunde O. Adebambo, Isa Danladi Jatau, Muthusamy Raman, Daniel Parker, Jonathan Rushton and Fiona M. Tomley

    Citation: Veterinary Research 2020 51:115

    Content type: Research article

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  9. Erysipelas, a disease caused by Erysipelothrix rhusiopathiae (ER), is an increasing problem in laying hens housed in cage-free systems. This study aimed to monitor immune responses during ER infection of naïve ch...

    Authors: Eva Wattrang, Helena Eriksson, Tomas Jinnerot, Maria Persson, Elisabeth Bagge, Robert Söderlund, Mohammad Naghizadeh and Tina Sørensen Dalgaard

    Citation: Veterinary Research 2020 51:114

    Content type: Research article

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  10. Chickens are highly susceptible to highly pathogenic avian influenza viruses (HPAIVs). However, the severity of infection varies depending of the viral strain and the genetic background of the host. In this st...

    Authors: Raúl Sánchez-González, Antonio Ramis, Miquel Nofrarías, Nabil Wali, Rosa Valle, Mónica Pérez, Albert Perlas and Natàlia Majó

    Citation: Veterinary Research 2020 51:113

    Content type: Research article

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  11. To increase expression levels of the PCV2 Cap(d41) protein, novel baculovirus surface display vectors with multiple expression cassettes were constructed to create recombinant baculoviruses BacSC-Cap(d41), Bac...

    Authors: Ya-Yi Chen, Wei-Chen Yang, Yu-Kang Chang, Chi-Young Wang, Wei-Ru Huang, Jyun-Yi Li, Kuo-Pin Chuang, Hung-Yi Wu, Ching-Dong Chang, Brent L. Nielsen and Hung-Jen Liu

    Citation: Veterinary Research 2020 51:112

    Content type: Research article

    Published on:

  12. In our previous studies, a novel T. spiralis peptidase (TsP) was identified among the excretory/secretory (ES) proteins of T. spiralis intestinal infective larvae (IIL) and T. spiralis at the adult worm (AW) stag...

    Authors: Jun Jun Lei, Yuan Yuan Hu, Fang Liu, Shu Wei Yan, Ruo Dan Liu, Shao Rong Long, Peng Jiang, Jing Cui and Zhong Quan Wang

    Citation: Veterinary Research 2020 51:111

    Content type: Research article

    Published on:

  13. Canine parvovirus (CPV) can cause acute and highly contagious bloody enteritis in dog. To obtain antibodies against CPV, hens were immunized with virus-like particles (VLP) of CPV-VP2. The IgY single chain fra...

    Authors: Shikun Ge, Long Xu, Ben Li, Fagang Zhong, Xiang Liu and Xiaoying Zhang

    Citation: Veterinary Research 2020 51:110

    Content type: Research article

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  14. Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species. Inc...

    Authors: Sonja Kittl, Thierry Francey, Isabelle Brodard, Francesco C. Origgi, Stéphanie Borel, Marie-Pierre Ryser-Degiorgis, Ariane Schweighauser and Joerg Jores

    Citation: Veterinary Research 2020 51:109

    Content type: Short report

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  15. Defective interfering particles (DIPs) of influenza virus are generated through incorporation of highly truncated forms of genome segments, mostly those coding polymerase complex proteins (PB2, PB1, PA). Such ...

    Authors: Edyta Świętoń, Karolina Tarasiuk and Krzysztof Śmietanka

    Citation: Veterinary Research 2020 51:108

    Content type: Research article

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  16. Trichinella spiralis maintains chronic infections within its host. Muscle larvae excretory-secretory products (MLES) typically induce parasite-specific immune responses such as the Th2 response and regulatory T c...

    Authors: Xuemin Jin, Xue Bai, Yong Yang, Jing Ding, Haining Shi, Baoquan Fu, Pascal Boireau, Mingyuan Liu and Xiaolei Liu

    Citation: Veterinary Research 2020 51:107

    Content type: Research article

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  17. Haemonchus contortus is a hematophagous endoparasite of small ruminants, which is responsible for huge economic losses in livestock sector. Hyaluronidase produced by infective larvae of H. contortus can degrade h...

    Authors: Xiangshu Yang, Sawar Khan, Xiaochao Zhao, Jiayan Zhang, Ayesha Nisar and Xingang Feng

    Citation: Veterinary Research 2020 51:106

    Content type: Research article

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  18. Neutrophils are the first barriers for resisting the invasion, proliferation, and damage caused by Salmonella Typhimurium. However, the mechanisms that control this resistance are not completely understood. In th...

    Authors: Tinghua Huang, Caiyun Jiang, Min Yang, Hong Xiao, Xiali Huang, Lingbo Wu and Min Yao

    Citation: Veterinary Research 2020 51:105

    Content type: Research article

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  19. Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is one of the most severe swine diseases that affects almost all swine-breeding countries. Nonstructural protein 2 (NSP2) is on...

    Authors: Shengliang Cao, Jiaqi Liu, Guofei Ding, Qingyuan Shao, Bin Wang, Yingchao Li, Jian Feng, Yuzhong Zhao, Sidang Liu and Yihong Xiao

    Citation: Veterinary Research 2020 51:104

    Content type: Research article

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  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Guowei Xu, Shouxing Xu, Xijuan Shi, Chaochao Shen, Junhong Hao, Minhao Yan, Dajun Zhang, Zixiang Zhu, Keshan Zhang, Haixue Zheng and Xiangtao Liu

    Citation: Veterinary Research 2020 51:103

    Content type: Correction

    Published on:

    The original article was published in Veterinary Research 2020 51:91

  21. Glaesserella parasuis (G. parasuis) causes porcine vascular inflammation and damage. Baicalin is reported to have antioxidant and anti-inflammatory functions. However, whether baicalin protects piglets against G....

    Authors: Shulin Fu, Ronghua Yin, Sanling Zuo, Jun Liu, Yunfei Zhang, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Zhongyuan Wu, Yongqing Hou and Chien-An Andy Hu

    Citation: Veterinary Research 2020 51:102

    Content type: Research article

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  22. Brucella ovis is a non-zoonotic rough Brucella that causes genital lesions, abortions and increased perinatal mortality in sheep and is responsible for important economic losses worldwide. Research on virulence f...

    Authors: Nieves Vizcaíno, Lara Pérez-Etayo, Raquel Conde-Álvarez, Maite Iriarte, Ignacio Moriyón and Amaia Zúñiga-Ripa

    Citation: Veterinary Research 2020 51:101

    Content type: Research article

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  23. Matrix metalloproteinases (MMPs) play an important role in intestinal extracellular matrix homeostasis. An overexpression of MMPs results in tissue destruction and local inflammation and has been associated wi...

    Authors: Lore Van Damme, Natasja Cox, Chana Callens, Freddy Haesebrouck, Michelle Dargatz, Richard Ducatelle, Filip Van Immerseel and Evy Goossens

    Citation: Veterinary Research 2020 51:100

    Content type: Research article

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  24. Probiotics as an effective and safe strategy for controlling Salmonella infection are much sought after, while autophagy is a central issue in eliminating intracellular pathogens of intestinal epithelial cells. I...

    Authors: Bingxin Chu, Yaohong Zhu, Jinhui Su, Bing Xia, Yunjing Zou, Jiawei Nie, Wei Zhang and Jiufeng Wang

    Citation: Veterinary Research 2020 51:99

    Content type: Research article

    Published on:

  25. Streptococcus agalactiae is one of the causative agents of subclinical mastitis, a common disease of dairy cows that causes great economic losses in the industry worldwide. It is thought that pathology is mainly ...

    Authors: Jinjin Tong, Mingwei Sun, Hua Zhang, Delian Yang, Yonghong Zhang, Benhai Xiong and Linshu Jiang

    Citation: Veterinary Research 2020 51:98

    Content type: Research article

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  26. Lipooligosaccharides (LOSs) are virulence determinants of Glaesserella parasuis, a pathogen of the respiratory tract of pigs. We previously reported that disruption of the galU or galE gene in G. parasuis results...

    Authors: Saixiang Feng, Aihua Chen, Xiaobing Wang, Zhichao Pan, Siqi Xu, Huiwen Yu, Bin Zhang and Ming Liao

    Citation: Veterinary Research 2020 51:97

    Content type: Research article

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  27. We analyzed the pathogenicity of a recent Japanese classical swine fever virus (CSFV) to wild boars via an experimental infection using boar-pig hybrids as an alternative to wild boars. We also investigated th...

    Authors: Katsuhiko Fukai, Tatsuya Nishi, Manabu Yamada and Mitsutaka Ikezawa

    Citation: Veterinary Research 2020 51:96

    Content type: Short report

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  28. The prevalence of TW I-type infectious bronchitis virus (IBV) has been increasing rapidly, and it has become the second most common genotype of IBV in China threatening the poultry industry. In this study, 1-d...

    Authors: Xiaorong Zhang, Kai Liao, Shuqin Chen, Kun Yan, Xubin Du, Chengcheng Zhang, Mengjiao Guo and Yantao Wu

    Citation: Veterinary Research 2020 51:95

    Content type: Research article

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  29. The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes...

    Authors: Pavlína Kellerová, Lucie Raisová Stuchlíková, Petra Matoušková, Karolína Štěrbová, Jiří Lamka, Martina Navrátilová, Ivan Vokřál, Barbora Szotáková and Lenka Skálová

    Citation: Veterinary Research 2020 51:94

    Content type: Research article

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  30. Fimbriae-mediated initial adherence is the initial and critical step required for enterotoxigenic Escherichia coli (ETEC) infection. Therefore, vaccine candidates have been developed that target these fimbriae an...

    Authors: Qiangde Duan, Shengmei Pang, Wenwen Wu, Boyu Jiang, Weiping Zhang, Siguo Liu, Xiaojun Wang, Zhiming Pan and Guoqiang Zhu

    Citation: Veterinary Research 2020 51:93

    Content type: Research article

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  31. Brucella is a genus of gram-negative bacteria that cause brucellosis. B. abortus and B. melitensis infect domestic ruminants while B. suis (biovars 1–3) infect swine, and all these bacteria but B. suis biovar 2 a...

    Authors: Beatriz Aragón-Aranda, María Jesús de Miguel, Leticia Lázaro-Antón, Miriam Salvador-Bescós, Amaia Zúñiga-Ripa, Ignacio Moriyón, Maite Iriarte, Pilar M. Muñoz and Raquel Conde-Álvarez

    Citation: Veterinary Research 2020 51:92

    Content type: Research article

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  32. Seneca Valley virus (SVV) is a non-encapsulated single-stranded positive-strand RNA virus whose transmission routes have not yet been fully elucidated. Exosomes have been implicated in the intercellular transp...

    Authors: Guowei Xu, Shouxing Xu, Xijuan Shi, Chaochao Shen, Junhong Hao, Minhao Yan, Dajun Zhang, Zixiang Zhu, Keshan Zhang, Haixue Zheng and Xiangtao Liu

    Citation: Veterinary Research 2020 51:91

    Content type: Research article

    Published on:

    The Correction to this article has been published in Veterinary Research 2020 51:103

  33. Avian coccidian parasites exhibit a high degree of site specificity in different Eimeria species. Although the underlying mechanism is unclear, an increasing body of evidence suggests that site specificity is due...

    Authors: Wenyu Li, Mingyue Wang, Yufeng Chen, Chen Chen, Xiaoqian Liu, Xiaoting Sun, Chuanxu Jing, Lixin Xu, Ruofeng Yan, Xiangrui Li and Xiaokai Song

    Citation: Veterinary Research 2020 51:90

    Content type: Research article

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  34. The disease caused by duck Tembusu virus (DTMUV) is characterized by severe egg-drop in laying ducks. Currently, the disease has spread to most duck-raising areas in China, leading to great economic losses in ...

    Authors: Ning Li, Jun Zhao, Yudong Yang, Yongqing Zeng and Sidang Liu

    Citation: Veterinary Research 2020 51:87

    Content type: Review

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  35. Influenza A viruses evolve rapidly to escape host immunity. In swine, this viral evolution has resulted in the emergence of multiple H1 and H3 influenza A virus (IAV) lineages in the United States (US) pig pop...

    Authors: Chong Li, Marie R. Culhane, Maxim Cheeran, Lucina Galina Pantoja, Micah L. Jansen, Deborah Amodie, Martha A. Mellencamp and Montserrat Torremorell

    Citation: Veterinary Research 2020 51:89

    Content type: Research article

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  36. Avian Metapneumovirus (aMPV) has been recognized as a respiratory pathogen of turkey and chickens for a long time. Recently, a crescent awareness of aMPV, especially subtype B, clinical and economic impact has...

    Authors: Giovanni Franzo, Matteo Legnardi, Giulia Mescolini, Claudia Maria Tucciarone, Caterina Lupini, Giulia Quaglia, Elena Catelli and Mattia Cecchinato

    Citation: Veterinary Research 2020 51:88

    Content type: Research article

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  37. Continued reports of infections with infectious bronchitis virus (IBV) variants have occurred since its first isolation in the 1930s. Currently, QX-like IBVs are the predominant circulating genotype around the...

    Authors: Lei Shao, Jing Zhao, Lihua Li, Xiuying Huang, Huiming Yang, Jinlong Cheng, Changqing Liu and Guozhong Zhang

    Citation: Veterinary Research 2020 51:86

    Content type: Research article

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  38. Streptococcus (S.) suis is a globally important swine pathogen, which comprises certain zoonotic serotypes. In this study, a detailed characterization of 88 porcine S. suis isolates was performed by analyzing cap...

    Authors: Simone Scherrer, Giuliana Rosato, Nathalie Spoerry Serrano, Marc J. A. Stevens, Fenja Rademacher, Jacques Schrenzel, Marcelo Gottschalk, Roger Stephan and Sophie Peterhans

    Citation: Veterinary Research 2020 51:85

    Content type: Research article

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  39. Newcastle disease (ND), which is caused by Newcastle disease virus (NDV), can cause heavy economic losses to the poultry industry worldwide. It is characterised by extensive pathologies of the digestive, respi...

    Authors: Zaib Ur Rehman, Shanhui Ren, Bin Yang, Xiaofeng Yang, Salman Latif Butt, Alia Afzal, Muhammad Irfan Malik, Yingjie Sun, Shengqing Yu, Chunchun Meng and Chan Ding

    Citation: Veterinary Research 2020 51:84

    Content type: Research article

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  40. Neospora caninum is an apicomplexan cyst-forming parasite that is considered one of the main causes of abortion. The pathogenic mechanisms associated with parasite virulence at the maternal-foetal interface that ...

    Authors: Laura Jiménez-Pelayo, Marta García-Sánchez, Esther Collantes-Fernández, Javier Regidor-Cerrillo, Pilar Horcajo, Daniel Gutiérrez-Expósito, José Espinosa, Julio Benavides, Koldo Osoro, Christiane Pfarrer and Luis Miguel Ortega-Mora

    Citation: Veterinary Research 2020 51:83

    Content type: Research article

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  41. In a study originally designed to find potential risk factors for bovine spongiform encephalopathy (BSE) we examined tissues from 403 Holstein Frisian cattle in total. These included 20 BSE cattle and their 23...

    Authors: Insa Dammann, Wiebke M. Wemheuer, Arne Wrede, Wilhelm E. Wemheuer, Amely Campe, Jutta Petschenka, Ulf Schulze-Sturm, Uwe Hahmann, Claus P. Czerny, Pia Münster, Bertram Brening, Lothar Kreienbrock, Christiane Herden and Walter J. Schulz-Schaeffer

    Citation: Veterinary Research 2020 51:82

    Content type: Research article

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  42. Climate change ranks among the most important issues globally, affecting geographic distributions of vectors and pathogens, and inducing losses in livestock production among many other damaging effects. We cha...

    Authors: Roberta Marques, Rodrigo F. Krüger, A. Townsend Peterson, Larissa F. de Melo, Natália Vicenzi and Daniel Jiménez-García

    Citation: Veterinary Research 2020 51:81

    Content type: Research article

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  43. Understudied, coinfections are more frequent in pig farms than single infections. In pigs, the term “Porcine Respiratory Disease Complex” (PRDC) is often used to describe coinfections involving viruses such as...

    Authors: Georges Saade, Céline Deblanc, Juliette Bougon, Corinne Marois-Créhan, Christelle Fablet, Gaël Auray, Catherine Belloc, Mily Leblanc-Maridor, Carl A. Gagnon, Jianzhong Zhu, Marcelo Gottschalk, Artur Summerfield, Gaëlle Simon, Nicolas Bertho and François Meurens

    Citation: Veterinary Research 2020 51:80

    Content type: Review

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  44. Encephalitozoonosis is a common infectious disease widely spread among rabbits. Encephalitozoon cuniculi, is considered as a zoonotic and emerging pathogen capable of infecting both immunocompetent and immunocomp...

    Authors: Edita Jeklova, Lenka Leva, Jan Matiasovic, Petra Ondrackova, Vladimir Kummer and Martin Faldyna

    Citation: Veterinary Research 2020 51:79

    Content type: Research article

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  45. A Trichinella spiralis aminopeptidase (TsAP) has been identified in intestinal infectious larvae (IIL) and adult worms (AW), but its biological function in the T. spiralis life cycle is unknown. The aim of this s...

    Authors: Kai Xia Guo, Ying Bai, Hua Nan Ren, Xiang Yuan Sun, Yan Yan Song, Ruo Dan Liu, Shao Rong Long, Xi Zhang, Peng Jiang, Zhong Quan Wang and Jing Cui

    Citation: Veterinary Research 2020 51:78

    Content type: Research article

    Published on:

  46. Mastitis, inflammation of the mammary gland, is a common disease of dairy animals. The disease is caused by bacterial infection ascending through the teat canal and mammary pathogenic Escherichia coli (MPEC) are ...

    Authors: Hagit Salamon, Einat Nissim-Eliraz, Oded Ardronai, Israel Nissan and Nahum Y. Shpigel

    Citation: Veterinary Research 2020 51:77

    Content type: Research article

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  47. Polyparasitism occurs when animals harbour multiple parasites concomitantly. It is a common occurrence but is generally understudied in wild and domestic animals. Fasciola hepatica and Echinococcus granulosus, wh...

    Authors: Christian Hidalgo, Caroll Stoore, Marcela Hernández and Rodolfo Paredes

    Citation: Veterinary Research 2020 51:76

    Content type: Research article

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  48. Ovine enzootic abortion (OEA) caused by the obligate intracellular bacterial pathogen Chlamydia abortus (C. abortus), is an endemic disease in most sheep-rearing countries worldwide. Following infection, C. abort...

    Authors: Sean R. Wattegedera, Morag Livingstone, Stephen Maley, Mara Rocchi, Susan Lee, Yvonne Pang, Nick M. Wheelhouse, Kevin Aitchison, Javier Palarea-Albaladejo, David Buxton, David Longbottom and Gary Entrican

    Citation: Veterinary Research 2020 51:75

    Content type: Research article

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  49. Q fever is a zoonosis caused by the intracellular bacterium Coxiella burnetii. In Europe, small ruminants are the main source of human Q fever. Small ruminant herds can be infectious during several lambing season...

    Authors: Hendrik I. J. Roest, Annemieke Dinkla, Ad P. Koets, Jacob Post and Lucien van Keulen

    Citation: Veterinary Research 2020 51:74

    Content type: Research article

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  50. Monocytes/macrophages, which are found in a variety of organs, maintain tissue homeostasis at a steady state and act as the first line of defence during pathogen-induced inflammation in the host. Most monocyte...

    Authors: Keesun Yu, Min Jeong Gu, Young Jin Pyung, Ki-Duk Song, Tae Sub Park, Seung Hyun Han and Cheol-Heui Yun

    Citation: Veterinary Research 2020 51:73

    Content type: Research article

    Published on:

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