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  1. Content type: Research article

    Thioredoxins (Trxs) play an important role in defending against oxidative stress and keeping disulfide bonding correct to maintain protein function. Edwardsiella piscicida, a severe fish pathogen, has been shown ...

    Authors: Bi-ying Wang, Hui-qin Huang, Shuang Li, Ping Tang, Hao-fu Dai, Jian-an Xian, Dong-mei Sun and Yong-hua Hu

    Citation: Veterinary Research 2019 50:26

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  2. Content type: Research article

    Staphylococcus aureus is the most commonly isolated pathogen from clinical bovine mastitis samples and a difficult pathogen to combat. Mesenchymal stem cells (MSC) are multipotent progenitor cells equipped with a...

    Authors: Berly Cahuascanco, Javiera Bahamonde, Olger Huaman, Miguel Jervis, Jahaira Cortez, Jaime Palomino, Alejandro Escobar, Patricio Retamal, Cristian G. Torres and Oscar Alejandro Peralta

    Citation: Veterinary Research 2019 50:25

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  3. Content type: Research article

    The impact of cortisol on Flavobacterium columnare biofilm formation was explored. Firstly, the dynamics of biofilm formation by one highly (HV) and one low virulent (LV) F. columnare isolate with and without the...

    Authors: Annelies Maria Declercq, Wenlong Cai, Eber Naranjo, Wilawan Thongda, Venessa Eeckhaut, Eva Bauwens, Covadonga Arias, Leonardo De La Fuente, Benjamin H. Beck, Miles D. Lange, Eric Peatman, Freddy Haesebrouck, Johan Aerts and Annemie Decostere

    Citation: Veterinary Research 2019 50:24

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  4. Content type: Research article

    Schistosomiasis is an important zoonotic disease affecting up to 40 kinds of animals and 250 million people. It has been reported that the miRNAs play a role in the metabolism, differentiation, development and...

    Authors: Jie Yu, Ying Yu, Qing Li, Muxin Chen, Haimo Shen, RuiXiang Zhang, Mingxin Song and Wei Hu

    Citation: Veterinary Research 2019 50:23

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  5. Content type: Research article

    Nuclear localization of paramyxovirus proteins is crucial for virus life cycle, including the regulation of viral replication and the evasion of host immunity. We previously showed that a recombinant Newcastle...

    Authors: Zhiqiang Duan, Shanshan Deng, Xinqin Ji, Jiafu Zhao, Chao Yuan and Hongbo Gao

    Citation: Veterinary Research 2019 50:22

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  6. Content type: Research article

    Brachyspira (B.) hyodysenteriae is widespread globally, and can cause mucohaemorrhagic colitis (swine dysentery, SD) with severe economic impact in infected herds. Typical strains of B. hyodysenteriae are strongl...

    Authors: Roderick M. Card, Tom La, Eric R. Burrough, Richard J. Ellis, Javier Nunez-Garcia, Jill R. Thomson, Maxime Mahu, Nyree D. Phillips, David J. Hampson, Judith Rohde and Alexander W. Tucker

    Citation: Veterinary Research 2019 50:21

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  7. Content type: Research article

    Avian leukosis virus subgroup J (ALV-J) infection can cause tumors and immunosuppression in infected chickens. Macrophages play a central role in host defense against invading pathogens. In this study, we disc...

    Authors: Min Feng, Tingting Xie, Yuanfang Li, Nan Zhang, Qiuyuan Lu, Yaohong Zhou, Meiqing Shi, Jingchen Sun and Xiquan Zhang

    Citation: Veterinary Research 2019 50:20

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  8. Content type: Research article

    Porcine circovirus type 2 (PCV2) is an economically important swine pathogen but some extra trigger factors are required for the development of PCV2-associated diseases. By evaluating cap protein expression, v...

    Authors: Nianhui Zhai, Kai Liu, Hu Li, Zixuan Liu, Hong Wang, Viktor I. Korolchuk, Bernadette Carroll, Cuiling Pan, Fang Gan, Kehe Huang and Xingxiang Chen

    Citation: Veterinary Research 2019 50:19

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  9. Content type: Research article

    The G1-H9N2 avian influenza virus (AIV) has caused significant economic losses in the commercial poultry industry due to reduced egg production and increased mortality. The field observations have shown that H...

    Authors: Giang Thu Nguyen, Fabienne Rauw, Mieke Steensels, Fiona Ingrao, Francesco Bonfante, Irit Davidson and Bénédicte Lambrecht

    Citation: Veterinary Research 2019 50:18

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  10. Content type: Research article

    Porcine circovirus-associated disease (PCVAD) is one of the most serious infectious diseases in pigs worldwide. The primary causative agent of PCVAD is porcine circovirus type 2 (PCV2), which can cause lymphoi...

    Authors: Gen Liu, Yanchao Wang, Shijin Jiang, Minmin Sui, Changying Wang, Li Kang, Yi Sun and Yunliang Jiang

    Citation: Veterinary Research 2019 50:17

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  11. Content type: Research article

    The highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) emerged in 2006 in China and caused great economic losses for the swine industry because of the lack of an effective vaccine...

    Authors: Shengliang Cao, Fangyuan Cong, Min Tan, Guofei Ding, Jiaqi Liu, Li Li, Yuzhong Zhao, Sidang Liu and Yihong Xiao

    Citation: Veterinary Research 2019 50:16

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  12. Content type: Research article

    The chicken gut is constantly exposed to harmful molecules and microorganisms which endanger the integrity of the intestinal wall. Strengthening intestinal mucosal integrity is a key target for feed additives ...

    Authors: Marisol Aguirre, Juhani Vuorenmaa, Eija Valkonen, Hannele Kettunen, Chana Callens, Freddy Haesebrouck, Richard Ducatelle, Filip Van Immerseel and Evy Goossens

    Citation: Veterinary Research 2019 50:15

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  13. Content type: Research article

    Piscine orthoreovirus (PRV) mediated diseases have emerged throughout salmonid aquaculture. Three PRV subtypes are currently reported as causative agents of or in association with diseases in different salmoni...

    Authors: Niccoló Vendramin, Dhamotharan Kannimuthu, Anne Berit Olsen, Argelia Cuenca, Lena Hammerlund Teige, Øystein Wessel, Tine Moesgaard Iburg, Maria Krudtaa Dahle, Espen Rimstad and Niels Jørgen Olesen

    Citation: Veterinary Research 2019 50:14

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  14. Content type: Research article

    Equine herpesvirus type 5 (EHV5) is a ubiquitous, yet obscure pathogen in the horse population and is commonly associated with fatal equine multinodular pulmonary fibrosis (EMPF). To date, little is known abou...

    Authors: Jolien Van Cleemput, Katrien C. K. Poelaert, Kathlyn Laval and Hans J. Nauwynck

    Citation: Veterinary Research 2019 50:13

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  15. Content type: Research article

    Infectious bronchitis virus (IBV) causes a major disease problem for the poultry industry worldwide. The currently used live-attenuated vaccines have the tendency to mutate and/or recombine with circulating fi...

    Authors: Hassanein H. Abozeid, Anandan Paldurai, Berin P. Varghese, Sunil K. Khattar, Manal A. Afifi, Sahar Zouelfakkar, Ayman H. El-Deeb, Magdy F. El-Kady and Siba K. Samal

    Citation: Veterinary Research 2019 50:12

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  16. Content type: Research article

    Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that is widespread in cattle. However, only a few studies about the pathogenesis of BoHV-4 primary infection have been reported. In the present study, ex viv...

    Authors: Bo Yang, Jiexiong Xie, Jolien Van Cleemput, Ruifang Wei, Geert Opsomer and Hans J. Nauwynck

    Citation: Veterinary Research 2019 50:11

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  17. Content type: Research article

    Contagious caprine pleuropneumonia (CCPP), caused by Mycoplasma capricolum subsp. capripneumoniae is a severe disease widespread in Africa and Asia. Limited knowledge is available on the pathogenesis of this orga...

    Authors: Anne Liljander, Flavio Sacchini, Michael H. Stoffel, Elise Schieck, Nadine Stokar-Regenscheit, Fabien Labroussaa, Martin Heller, Jeremy Salt, Joachim Frey, Laurent Falquet, Danny Goovaerts and Joerg Jores

    Citation: Veterinary Research 2019 50:10

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  18. Content type: Research article

    As a key cellular transcription factor that plays a central role in cellular responses to a broad range of stress factors, p53 has generally been considered as a host cell restriction factor for various viral ...

    Authors: Xun Li, Wei Zhang, Yunjia Liu, Jiaxun Xie, Chuanhuo Hu and Xiaoye Wang

    Citation: Veterinary Research 2019 50:9

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  19. Content type: Research article

    The rumen epithelium of sheep serves as an immune interface with the environment and secretes antimicrobial peptides with bactericidal function against various pathogens. Sheep beta-defensin-1 (SBD-1), an anti...

    Authors: Xin Jin, Man Zhang, Gui-fang Cao and Yin-feng Yang

    Citation: Veterinary Research 2019 50:8

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  20. Content type: Research article

    Haemonchus contortus is one of the most pathogenic gastrointestinal nematodes in small ruminants. To understand molecular mechanisms underlying host resistance to this parasite, we used RNA-sequencing technology ...

    Authors: Runfeng Zhang, Fang Liu, Peter Hunt, Congjun Li, Lichun Zhang, Aaron Ingham and Robert W. Li

    Citation: Veterinary Research 2019 50:7

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  21. Content type: Research article

    Chronic wasting disease (CWD) is a fatal prion disease which infects deer, elk and moose. CWD was first described as a wasting syndrome in captive deer in Colorado and Wyoming wildlife facilities from 1967 to ...

    Authors: Brent Race, Katie Williams and Bruce Chesebro

    Citation: Veterinary Research 2019 50:6

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  22. Content type: Research article

    During 2007–2009 and 2012–2014, avian influenza virus (AIV) was studied in a wild avian community of a northern Spanish wetland using non-invasive sampling methods and host identification by COI barcoding. The ai...

    Authors: Olalla Torrontegi, Vega Alvarez, Pelayo Acevedo, Xeider Gerrikagoitia, Ursula Höfle and Marta Barral

    Citation: Veterinary Research 2019 50:4

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  23. Content type: Research article

    Echinococcosis is a zoonotic infection caused by cestode species of the genus Echinococcus, with limited treatment options. It is urgent to develop new anti-hydatid agent. In this paper, we reported anacardic aci...

    Authors: Miaomiao Yuan, Xiaoxia Song, Wei Lv, Qi Xin, Li Wang, Qi Gao, Guochao Zhang, Wenzhen Liao, Sen Lian and Tao Jing

    Citation: Veterinary Research 2019 50:3

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  24. Content type: Research article

    Porcine rotaviruses cause severe economic losses in the Korean swine industry due to G- and P-genotype mismatches between the predominant field and vaccine strains. Here, we developed a live attenuated trivale...

    Authors: Jun-Gyu Park, Mia Madel Alfajaro, Eun-Hyo Cho, Ji-Yun Kim, Mahmoud Soliman, Yeong-Bin Baek, Chul-Ho Park, Ju-Hwan Lee, Kyu-Yeol Son, Kyoung-Oh Cho and Mun-Il Kang

    Citation: Veterinary Research 2019 50:2

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  25. Content type: Review

    CD4 is a nonpolymorphic transmembrane glycoprotein molecule that is expressed on the surface of T-helper cells and plays an essential role in the immune response. It functions as a coreceptor with the T-cell r...

    Authors: Hassan Ashfaq, Hatem Soliman, Mona Saleh and Mansour El-Matbouli

    Citation: Veterinary Research 2019 50:1

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  26. Content type: Research article

    Epizootic rabbit enteropathy (ERE) represents one of the most devastating diseases affecting rabbit farms. Previous studies showing transmissibility of disease symptoms through oral inoculation of intestinal c...

    Authors: Ana Djukovic, Marc Garcia-Garcera, Eugenio Martínez-Paredes, Sandrine Isaac, Alejandro Artacho, Jorge Martínez and Carles Ubeda

    Citation: Veterinary Research 2018 49:123

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  27. Content type: Short report

    BSE infectivity in mesentery fat is most likely associated with embedded nervous tissue. To prove this mesentery containing celiac ganglion was taken from oral BSE infected cattle in different stages of the di...

    Authors: Christine Fast, Markus Keller, Martin Kaatz, Ute Ziegler and Martin H. Groschup

    Citation: Veterinary Research 2018 49:122

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  28. Content type: Research article

    Peripheral blood transcriptome is an important intermediate data source for investigating the mechanism of Salmonella invasion, proliferation, and transmission. We challenged 4-week old piglets with Salmonella en...

    Authors: Tinghua Huang, Xiali Huang, Bomei Shi, Fangfang Wang, Wenzhao Feng and Min Yao

    Citation: Veterinary Research 2018 49:121

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  29. Content type: Research article

    Recently, bacterial small RNA (sRNA) has been shown to be involved as a key regulator in stress responses. sRNAs of Edwardsiella piscicida, an important aquatic pathogen, are not well characterized to date. In th...

    Authors: He-he Du, Hai-Zhen Zhou, Ping Tang, Hui-qin Huang, Min Liu and Yong-hua Hu

    Citation: Veterinary Research 2018 49:120

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  30. Content type: Research article

    Trichinellosis is one of the most serious foodborne parasitic zoonosis with worldwide distribution, and it is necessary to develop a vaccine to interrupt transmission from animals to humans. Trichinella spiralis ...

    Authors: Xin Qi, Yue Han, Peng Jiang, Xin Yue, Hua Nan Ren, Ge Ge Sun, Shao Rong Long, Chuan Yu, Xiang Chao Cheng, Jing Cui and Zhong Quan Wang

    Citation: Veterinary Research 2018 49:119

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  31. Content type: Research article

    The presence of pneumoviruses in pigs is poorly documented. In this study, we used the published sequence of the nucleoprotein (N) of the recently identified Swine Orthopneumovirus (SOV) to express and purify SOV...

    Authors: Charles-Adrien Richard, Caroline Hervet, Déborah Ménard, Irina Gutsche, Valérie Normand, Fanny Renois, François Meurens and Jean-François Eléouët

    Citation: Veterinary Research 2018 49:118

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  32. Content type: Research article

    Paratuberculosis (PTB) or Johne’s disease is a contagious enteritis of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). Ovine PTB is less understood than bovine PTB, especially concerning pa...

    Authors: Salvatore Pisanu, Tiziana Cubeddu, Carla Cacciotto, Ylenia Pilicchi, Daniela Pagnozzi, Sergio Uzzau, Stefano Rocca and Maria Filippa Addis

    Citation: Veterinary Research 2018 49:117

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  33. Content type: Research article

    In animal prion diseases, including bovine spongiform encephalopathy (BSE) in cattle, chronic wasting disease in cervids, and scrapie in sheep and goats, a disease-associated isoform of prion protein (PrPd) accum...

    Authors: Kohtaro Miyazawa, Kentaro Masujin, Yuichi Matsuura, Yoshifumi Iwamaru, Takashi Yokoyama and Hiroyuki Okada

    Citation: Veterinary Research 2018 49:116

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  34. Content type: Research article

    Staphylococcus aureus is a versatile opportunistic pathogen, causing disease in human and animal species. Its pathogenicity is linked to the ability of S. aureus to secrete immunomodulatory molecules. These evasi...

    Authors: Kirsten J. Koymans, Louris J. Feitsma, Adinda Bisschop, Eric G. Huizinga, Jos A. G. van Strijp, Carla J. C. de Haas and Alex J. McCarthy

    Citation: Veterinary Research 2018 49:115

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  35. Content type: Research article

    Mycoplasma hyopneumoniae is an important respiratory pathogen that causes great economic losses to the pig industry worldwide. Although some putative virulence factors have been reported, pathogenesis remains poo...

    Authors: Yanfei Yu, Maojun Liu, Lizhong Hua, Mingjun Qiu, Wei Zhang, Yanna Wei, Yuan Gan, Zhixin Feng, Guoqing Shao and Qiyan Xiong

    Citation: Veterinary Research 2018 49:114

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  36. Content type: Research article

    The aim of the study was to analyze acute phase protein and cathelicidin gene responses to small ruminant lentivirus (SRLV) infection in goats. In uninfected goats, we found higher Cp and lower Fbγ mRNA levels in...

    Authors: Daria Reczyńska, Magdalena Zalewska, Michał Czopowicz, Jarosław Kaba, Lech Zwierzchowski and Emilia Bagnicka

    Citation: Veterinary Research 2018 49:113

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  37. Content type: Research article

    The presence of components of the RNA interference (RNAi) pathway in Psoroptes ovis, an ectoparasitic mite responsible for psoroptic mange, was investigated through interrogation of the P. ovis genome. Homologues...

    Authors: Edward J. Marr, Harry W. Wright, Neil D. Sargison, Alasdair J. Nisbet and Stewart T. G. Burgess

    Citation: Veterinary Research 2018 49:112

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  38. Content type: Research article

    Digital dermatitis (DD) presents as painful, ulcerative or proliferative lesions that lead to bovine lameness affecting economic efficiency and animal welfare. Although DD etiological agent(s) have not been es...

    Authors: Caroline Beninger, Syed Ali Naqvi, Sohail Naushad, Karin Orsel, Chris Luby, Hooman Derakhshani, Ehsan Khafipour and Jeroen De Buck

    Citation: Veterinary Research 2018 49:111

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  39. Content type: Research article

    The natural reservoir for all influenza A viruses (IAVs) is wild birds, particularly dabbling ducks. During the autumn, viral prevalence can be very high in dabbling ducks (> 30%) in the Northern Hemisphere, a...

    Authors: Michelle Wille, Caroline Bröjer, Åke Lundkvist and Josef D. Järhult

    Citation: Veterinary Research 2018 49:110

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  40. Content type: Research article

    Streptococcus suis is a swine pathogen and zoonotic agent responsible for meningitis and septic shock. Although several putative virulence factors have been described, the initial steps of the S. suis pathogenesi...

    Authors: Audrey Dumesnil, Jean-Philippe Auger, David Roy, Désirée Vötsch, Maren Willenborg, Peter Valentin-Weigand, Pyong Woo Park, Daniel Grenier, Nahuel Fittipaldi, Josée Harel and Marcelo Gottschalk

    Citation: Veterinary Research 2018 49:109

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  41. Content type: Research article

    This paper describes the results of two experiments regarding porcine reproductive and respiratory syndrome virus (PRRSV1): the first one studied the existence of bottlenecks in an experimental one-to-one mode...

    Authors: Martí Cortey, Gastón Arocena, Emanuela Pileri, Gerard Martín-Valls and Enric Mateu

    Citation: Veterinary Research 2018 49:107

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  42. Content type: Research article

    Endogenous transplacental transmission, which occurs during pregnancy as the result of reactivation of a latent infection in the dam, is the main mechanism of propagation of Neospora caninum within cattle herds. ...

    Authors: Marta González-Warleta, José Antonio Castro-Hermida, Carmen Calvo, Valentín Pérez, Daniel Gutiérrez-Expósito, Javier Regidor-Cerrillo, Luis Miguel Ortega-Mora and Mercedes Mezo

    Citation: Veterinary Research 2018 49:106

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  43. Content type: Short report

    African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced...

    Authors: Susan J. Dennis, Martha M. O’Kennedy, Daria Rutkowska, Tsepo Tsekoa, Carina W. Lourens, Inga I. Hitzeroth, Ann E. Meyers and Edward P. Rybicki

    Citation: Veterinary Research 2018 49:105

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  44. Content type: Research article

    The respiratory tract is a key organ for many avian pathogens as well as a major route for vaccination in the poultry industry. To improve immune responses after vaccination of chickens through increased uptak...

    Authors: Kate Sutton, Taiana Costa, Andreas Alber, Karen Bryson, Dominika Borowska, Adam Balic, Pete Kaiser, Mark Stevens and Lonneke Vervelde

    Citation: Veterinary Research 2018 49:104

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  45. Content type: Correction

    In the original publication of this article [1], the author found the brand of vimentin antibody was wrong in Fig. 3. The legend of Fig. 3, ‘mouse anti-vimentin mAb (Cell Signaling Technology) at 4 °C overnigh...

    Authors: Xiao‑Bo Chang, Yong‑Qian Yang, Jia‑Cong Gao, Kuan Zhao, Jin‑Chao Guo, Chao Ye, Cheng‑Gang Jiang, Zhi‑Jun Tian, Xue‑Hui Cai, Guang‑Zhi Tong and Tong‑Qing An

    Citation: Veterinary Research 2018 49:103

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    The original article was published in Veterinary Research 2018 49:75

  46. Content type: Research article

    Many viral proteins are related to suppressing apoptosis in target cells and are hence beneficial to viral replication. The V protein of Newcastle disease virus (NDV) is one such protein that plays an importan...

    Authors: Caiying Wang, Zhili Chu, Wenkai Liu, Yu Pang, Xiaolong Gao, Qiuxia Tang, Jiangang Ma, Kejia Lu, Fathalrhman E. A. Adam, Ruyi Dang, Sa Xiao, Xinglong Wang and Zengqi Yang

    Citation: Veterinary Research 2018 49:102

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  47. Content type: Research article

    Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to investigate the role of methyl gallate (MG) i...

    Authors: Biruk Tesfaye Birhanu, Na-Hye Park, Seung-Jin Lee, Md Akil Hossain and Seung-Chun Park

    Citation: Veterinary Research 2018 49:101

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  48. Content type: Research article

    Novel compounds and more efficient treatment options are urgently needed for the treatment of cystic echinococcosis (CE), which is caused by Echinococcus granulosus. The decoction of Sophora moorcroftiana (Fabace...

    Authors: Yanping Luo, Guochao Zhang, Xun Liu, Miaomiao Yuan, Qi Gao, Haijun Gao, Lixin Ke, Xinxing Zhang, Yanbin Shi, Xingming Ma, Lifeng Zhang and Kaizhong Dong

    Citation: Veterinary Research 2018 49:100

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