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  1. Due to increased anthelmintic resistance, complementary methods to drugs are necessary to control gastrointestinal nematodes (GIN). Vaccines are an environmentally-friendly and promising option. In a previous ...

    Authors: Cynthia Machín, Yolanda Corripio-Miyar, Julia N. Hernández, Tara Pérez-Hernández, Adam D. Hayward, Harry W. Wright, Daniel R. G. Price, Jacqueline B. Matthews, Tom N. McNeilly, Alasdair J. Nisbet and Jorge F. González

    Citation: Veterinary Research 2021 52:89

    Content type: Research article

    Published on:

  2. Toll-like receptor 19 (Tlr19) is a fish-specific TLR that plays a critical role in innate immunity. In the present study, we aimed to identify tlr19 from common carp (Cyprinus carpio L.) and explored its expressi...

    Authors: Shijuan Shan, Rongrong Liu, Hanxiao Feng, Fei Meng, Muhanmmad Aizaz and Guiwen Yang

    Citation: Veterinary Research 2021 52:88

    Content type: Research article

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  3. The porcine epidemic diarrhea virus (PEDV) causes a highly contagious disease in pigs, which is one of the most devastating viral diseases of swine in the world. In China, PEDV was first confirmed in 1984 and ...

    Authors: Pei-Hua Wang, Ya-Qian Li, Yuan-Qing Pan, Yan-Yan Guo, Fan Guo, Rui-Zhu Shi and Li Xing

    Citation: Veterinary Research 2021 52:87

    Content type: Research article

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  4. Porcine deltacoronavirus (PDCoV) is a newly discovered swine enteropathogenic coronavirus with worldwide distribution. However, efficient strategies to prevent or treat the infection remain elusive. Our in vit...

    Authors: Cong Duan, Junchi Wang, Yi Liu, Jialu Zhang, Jianyong Si, Zhihui Hao and Jiufeng Wang

    Citation: Veterinary Research 2021 52:86

    Content type: Research article

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  5. Trichinellosis, which is caused by nematodes of the genus Trichinella, is one of the most important zoonotic parasite diseases in the world. A rapid and sensitive immunochromatographic strip (ICS) based on Eu (II...

    Authors: Xinyu Wang, Bin Tang, Ying Zhao, Jing Ding, Nan Wang, Yan Liu, Zijian Dong, Xiangdong Sun, Quangang Xu, Mingyuan Liu and Xiaolei Liu

    Citation: Veterinary Research 2021 52:85

    Content type: Research article

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  6. Lamb survival is an important welfare and productivity issue for sheep industries worldwide. Lower lamb survival has been reported for primiparous ewes, but the causes of this are not well studied. The aim of ...

    Authors: Tom Clune, Shane Besier, Sam Hair, Serina Hancock, Amy Lockwood, Andrew Thompson, Martina Jelocnik and Caroline Jacobson

    Citation: Veterinary Research 2021 52:84

    Content type: Research article

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  7. Mannheimia haemolytica-induced bovine respiratory disease causes loss of millions of dollars to Canadian cattle industry. Current antimicrobials are proving to be ineffective and leave residues in meat. Antimicro...

    Authors: Harpreet Dhingra, Kamaljit Kaur and Baljit Singh

    Citation: Veterinary Research 2021 52:83

    Content type: Research article

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  8. Toxoplasma gondii is an important zoonotic agent with high genetic diversity, complex epidemiology, and variable clinical outcomes in animals and humans. In veterinary medicine, this apicomplexan parasite is cons...

    Authors: Mercedes Fernández-Escobar, Rafael Calero-Bernal, Javier Regidor-Cerrillo, Raquel Vallejo, Julio Benavides, Esther Collantes-Fernández and Luis Miguel Ortega-Mora

    Citation: Veterinary Research 2021 52:82

    Content type: Research article

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  9. This study was conducted to investigate the impacts of graded severity of Eimeria maxima infection on the growth performance and intestine health of broiler chickens. Four different levels of E. maxima-challenged...

    Authors: Po-Yun Teng, Janghan Choi, Yuguo Tompkins, Hyun Lillehoj and Woo Kim

    Citation: Veterinary Research 2021 52:81

    Content type: Research article

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  10. Mycoplasma hyorhinis infects pigs causing polyserositis and polyarthritis, and has also been reported in a variety of human tumor tissues. The occurrence of disease is often linked with the systemic invasion of t...

    Authors: Jia Wang, Yao Li, Longji Pan, Jun Li, Yanfei Yu, Beibei Liu, Muhammad Zubair, Yanna Wei, Bala Pillay, Ademola Olufolahan Olaniran, Thamsanqa E. Chiliza, Guoqing Shao, Zhixin Feng and Qiyan Xiong

    Citation: Veterinary Research 2021 52:80

    Content type: Research article

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  11. Aptamers are small nucleic acids that fold in a three-dimensional conformation allowing them to bind specifically to a target. This target can be an organic molecule, free or carried in cells or tissues, or in...

    Authors: Solène Niederlender, Jean-Jacques Fontaine and Grégory Karadjian

    Citation: Veterinary Research 2021 52:79

    Content type: Review

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  12. In vivo study of tissue or organ biology in mammals is very complex and progress is slowed by poor accessibility of samples and ethical concerns. Fortunately, however, advances in stem cell identification and ...

    Authors: Laurence Finot, Eric Chanat and Frederic Dessauge

    Citation: Veterinary Research 2021 52:78

    Content type: Review

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  13. The number and severity of diseases affecting lung development and adult respiratory function have stimulated great interest in developing new in vitro models to study lung in different species. Recent breakth...

    Authors: Fabienne Archer, Alexandra Bobet-Erny and Maryline Gomes

    Citation: Veterinary Research 2021 52:77

    Content type: Review

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  14. The Hippo signalling pathway plays a vital role in organ size control, cell proliferation, apoptosis, and immune regulation. In this study, a Hippo homologue with three isoforms (named MnHippo-a, MnHippo-b, and M...

    Authors: Ying Huang and Qian Ren

    Citation: Veterinary Research 2021 52:76

    Content type: Research article

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  15. Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis in humans and various animals. The threat of brucellosis has increased, yet currently available live attenuated vaccines ...

    Authors: Xiaodong Zai, Ying Yin, Fengyu Guo, Qiaoling Yang, Ruihua Li, Yaohui Li, Jun Zhang, Junjie Xu and Wei Chen

    Citation: Veterinary Research 2021 52:75

    Content type: Research article

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  16. Due to the substantial genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV), commercial PRRS vaccines fail to provide sufficient cross protection. Previous studies have confirmed th...

    Authors: Nanhua Chen, Shubin Li, Yunfei Tian, Xinshuai Li, Shuai Li, Jixiang Li, Ming Qiu, Zhe Sun, Yanzhao Xiao, Xilin Yan, Hong Lin, Xiuling Yu, Kegong Tian, Shaobin Shang and Jianzhong Zhu

    Citation: Veterinary Research 2021 52:74

    Content type: Research article

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  17. Porcine Parvovirus (PPV), a pathogen causing porcine reproductive disorders, encodes two capsid proteins (VP1 and VP2) and three nonstructural proteins (NS1, NS2 and SAT) in infected cells. The PPV NS2 mRNA is...

    Authors: Songbiao Chen, Bichen Miao, Nannan Chen, Caiyi Chen, Ting Shao, Xuezhi Zhang, Lingling Chang, Xiujuan Zhang, Qian Du, Yong Huang and Dewen Tong

    Citation: Veterinary Research 2021 52:73

    Content type: Research article

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  18. Typical two-dimensional (2D) culture models of skeletal muscle-derived cells cannot fully recapitulate the organization and function of living muscle tissues, restricting their usefulness in in-depth physiolog...

    Authors: Frederic Dessauge, Cindy Schleder, Marie-Hélène Perruchot and Karl Rouger

    Citation: Veterinary Research 2021 52:72

    Content type: Review

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  19. Gasdermin D (GSDMD), a member of the gasdermin protein family, is a caspase substrate, and its cleavage is required for pyroptosis and IL-1β secretion. To date, the role and regulatory mechanism of GSDMD durin...

    Authors: Zhen-Zhen Liu, Yong-Jun Yang, Feng-Hua Zhou, Ke Ma, Xiao-Qi Lin, Shi-Qing Yan, Yu Gao and Wei Chen

    Citation: Veterinary Research 2021 52:71

    Content type: Research article

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  20. Paratuberculosis is a disease of ruminants caused by Mycobacterium avium subsp. paratuberculosis (Map). Vaccination is the most cost-effective control method. However, despite the fact that macrophages are the ma...

    Authors: Noive Arteche-Villasol, Daniel Gutiérrez-Expósito, Raquel Vallejo, Jose Espinosa, Natalia Elguezabal, Iraia Ladero-Auñon, Marcos Royo, María del Carmen Ferreras, Julio Benavides and Valentín Pérez

    Citation: Veterinary Research 2021 52:69

    Content type: Research article

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  21. Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the serovars 4, 5/12, 7, 1, and 13 were t...

    Authors: Nubia Macedo, Marcelo Gottschalk, Katrin Strutzberg-Minder, Chao Nguyen Van, Lijun Zhang, Geng Zou, Rui Zhou, Thaire Marostica, Maria Jose Clavijo, Alexander Tucker and Virginia Aragon

    Citation: Veterinary Research 2021 52:68

    Content type: Research article

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  22. Mycoplasma hyopneumoniae (M. hyopneumoniae) is one of the primary agents involved in the porcine respiratory disease complex, economically one of the most important diseases in pigs worldwide. The pathogen adhere...

    Authors: Dominiek Maes, Filip Boyen, Bert Devriendt, Peter Kuhnert, Artur Summerfield and Freddy Haesebrouck

    Citation: Veterinary Research 2021 52:67

    Content type: Review

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  23. Cystic echinococcosis is a zoonotic disease caused by the metacestode of Echinococcus granulosus sensu lato. The disease is characterized by the development of cystic structures inside viscera of the intermediate...

    Authors: Christian Hidalgo, Caroll Stoore, María Soledad Baquedano, Ismael Pereira, Carmen Franco, Marcela Hernández and Rodolfo Paredes

    Citation: Veterinary Research 2021 52:66

    Content type: Research article

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  24. Salmonid Rickettsial Septicaemia (SRS), caused by Piscirickettsia salmonis, is the most important infectious disease in the Chilean salmon farming industry. An opportunity to control this disease is to use functi...

    Authors: Javiera Pérez-Valenzuela, Madelaine Mejías, Daniela Ortiz, Pablo Salgado, Liliana Montt, Ignacio Chávez-Báez, Francisca Vera-Tamargo, Dinka Mandakovic, Jurij Wacyk and Rodrigo Pulgar

    Citation: Veterinary Research 2021 52:64

    Content type: Research article

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  25. The TonB system is generally considered as an energy transporting device for the absorption of nutrients. Our recent study showed that deletion of this system caused a significantly increased sensitivity of Aerom...

    Authors: Yuhao Dong, Qing Li, Jinzhu Geng, Qing Cao, Dan Zhao, Mingguo Jiang, Shougang Li, Chengping Lu and Yongjie Liu

    Citation: Veterinary Research 2021 52:63

    Content type: Research article

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  26. Communications via quorum sensing (QS) between non-aureus staphylococci (NAS) and Staphylococcus (S.) aureus in the bovine mammary gland remains largely unexplored. We determined whether 34 S. chromogenes, 11 S. ...

    Authors: Bruno Toledo-Silva, Fernando Nogueira de Souza, Sofie Piepers, Kristien Mertens, Freddy Haesebrouck and Sarne De Vliegher

    Citation: Veterinary Research 2021 52:62

    Content type: Research article

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  27. Infectious bursal disease virus (IBDV) and fowl adenovirus serotype 4 (FAdV-4) cause infectious bursal disease (IBD) and hydropericardium-hepatitis syndrome, respectively. Recently, studies have reported co-in...

    Authors: A-hui Xu, Lu Sun, Kai-hang Tu, Qing-yuan Teng, Jia Xue and Guo-zhong Zhang

    Citation: Veterinary Research 2021 52:61

    Content type: Research article

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  28. Influenza A viruses (IAVs) are common causes of respiratory infection in pigs. The objective of this study was to characterize the circulation of IAVs between weaning and market age on the basis of development...

    Authors: Juliana Bonin Ferreira, Zvonimir Poljak, Robert Friendship, Éva Nagy, Greg Wideman and Helena Grgić

    Citation: Veterinary Research 2021 52:60

    Content type: Research article

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  29. The unconventional infectious agents of transmissible spongiform encephalopathies (TSEs) are prions. Their infectivity co-appears with PrPSc, aberrant depositions of the host’s cellular prion protein (PrPC). Succ...

    Authors: Jan P. M. Langeveld, Anne Balkema-Buschmann, Dieter Becher, Achim Thomzig, Romolo Nonno, Olivier Andréoletti, Aart Davidse, Michele A. Di Bari, Laura Pirisinu, Umberto Agrimi, Martin H. Groschup, Michael Beekes and Jason Shih

    Citation: Veterinary Research 2021 52:59

    Content type: Research article

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  30. Mycoplasma bovis (M. bovis) is a significant worldwide pathogen of cattle. Neutrophils have an important role in the innate immune response during infection with M. bovis. However, even though neutrophils accumul...

    Authors: Satoshi Gondaira, Koji Nishi, Jumpei Fujiki, Hidetomo Iwano, Reina Watanabe, Ayako Eguchi, Yuki Hirano, Hidetoshi Higuchi and Hajime Nagahata

    Citation: Veterinary Research 2021 52:58

    Content type: Research article

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  31. The diversity of goat scrapie strains in Europe has recently been studied using bioassays in a wide collection of rodent models, resulting in the classification of classical scrapie into four different categor...

    Authors: Alba Marín-Moreno, Patricia Aguilar-Calvo, Juan Carlos Espinosa, María Zamora-Ceballos, José Luis Pitarch, Lorenzo González, Natalia Fernández-Borges, Leonor Orge, Olivier Andréoletti, Romolo Nonno and Juan María Torres

    Citation: Veterinary Research 2021 52:57

    Content type: Research article

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  32. ELISA methods are the diagnostic tools recommended for the serological diagnosis of Coxiella burnetii infection in ruminants but their respective diagnostic performances are difficult to assess because of the abs...

    Authors: Thibaut Lurier, Elodie Rousset, Patrick Gasqui, Carole Sala, Clément Claustre, David Abrial, Philippe Dufour, Renée de Crémoux, Kristel Gache, Marie Laure Delignette-Muller, Florence Ayral and Elsa Jourdain

    Citation: Veterinary Research 2021 52:56

    Content type: Research article

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  33. Cell-mediated immune responses to Mycobacterium avium subsp. paratuberculosis (MAP) are regulated by various types of T lymphocytes. The aim of this study was to quantitate T cell subsets in the mid-ileum of cows...

    Authors: Caitlin J. Jenvey, Adrienne L. Shircliff, Elsa Obando Marrero and Judith R. Stabel

    Citation: Veterinary Research 2021 52:55

    Content type: Research article

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  34. Trypanosoma cruzi is a zoonotic parasite endemic in the southern US and the Americas, which may frequently infect dogs, but limited information is available about infections in cats. We surveyed a convenience sam...

    Authors: Eric Dumonteil, Hans Desale, Weihong Tu, Brandy Duhon, Wendy Wolfson, Gary Balsamo and Claudia Herrera

    Citation: Veterinary Research 2021 52:53

    Content type: Research article

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  35. Long non-coding RNAs (lncRNAs) are a new arm of gene regulatory mechanism as discovered by sequencing techniques and follow-up functional studies. The lncRNAs regulation of pseudorabies virus (PRV) infection h...

    Authors: Linlin Fang, Yanni Gao, Xing Liu, Juan Bai, Ping Jiang and XianWei Wang

    Citation: Veterinary Research 2021 52:52

    Content type: Research article

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  36. Trichinella spiralis is an important foodborne parasitic nematode distributed worldwide that infects humans and animals. Glutaminase (GLS) is an important gene in the glutamine-dependent acid resistance (AR) syst...

    Authors: Yuan Gao, Xiaoqing Meng, Xiao Yang, Shi Meng, Caixia Han, Xiaoyun Li, Shuang Wang, Wei Li and Mingxin Song

    Citation: Veterinary Research 2021 52:51

    Content type: Research article

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  37. Streptococcus suis (S. suis) is an important zoonotic pathogen that causes septicaemia, meningitis and streptococcal toxic shock-like syndrome in its host, and recent studies have shown that S. suis could be comp...

    Authors: Yinchu Zhu, Jiale Ma, Yue Zhang, Xiaojun Zhong, Qiankun Bai, Wenyang Dong, Zihao Pan, Guangjin Liu, Cun Zhang and Huochun Yao

    Citation: Veterinary Research 2021 52:50

    Content type: Research article

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  38. Streptococcus suis is one of the most important bacterial swine pathogens affecting post-weaned piglets, causing mainly meningitis, arthritis and sudden death. It not only results in severe economic losses but al...

    Authors: Milan R. Obradovic, Mariela Segura, Joaquim Segalés and Marcelo Gottschalk

    Citation: Veterinary Research 2021 52:49

    Content type: Review

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  39. Iron is essential for most bacteria to survive, but excessive iron leads to damage by the Fenton reaction. Therefore, the concentration of intracellular free iron must be strictly controlled in bacteria. Riemerel...

    Authors: Mi Huang, Mafeng Liu, Jiajun Liu, Dekang Zhu, Qianying Tang, Renyong Jia, Shun Chen, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Sai Mao, Qun Gao, Di Sun…

    Citation: Veterinary Research 2021 52:48

    Content type: Research article

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  40. Mycobacterium avium subsp. paratuberculosis (MAP) is a causative agent of Johne’s disease, which is a chronic granulomatous enteropathy in ruminants. Determining the genetic diversity of MAP is necessary to under...

    Authors: Jaewon Lim, Hong-Tae Park, Seyoung Ko, Hyun-Eui Park, Gyumin Lee, Suji Kim, Min-Kyoung Shin, Han Sang Yoo and Donghyuk Kim

    Citation: Veterinary Research 2021 52:46

    Content type: Research article

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  41. Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines...

    Authors: Zhigang Zhang, Tianshu Zhai, Mingshuo Li, Kun Zhang, Jingrui Li, Xu Zheng, Chaonan Tian, Rui Chen, Jianhui Dong, En-Min Zhou, Yuchen Nan and Chunyan Wu

    Citation: Veterinary Research 2021 52:45

    Content type: Research article

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  42. Small non-coding RNA RyhB is a key regulator of iron homeostasis in bacteria by sensing iron availability in the environment. Although RyhB is known to influence bacterial virulence by interacting with iron me...

    Authors: Binjie Chen, Xianchen Meng, Jie Ni, Mengping He, Yanfei Chen, Pengpeng Xia, Heng Wang, Siguo Liu, Guoqiang Zhu and Xia Meng

    Citation: Veterinary Research 2021 52:44

    Content type: Research article

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  43. Organoids are self-organizing, self-renewing three-dimensional cellular structures that resemble organs in structure and function. They can be derived from adult stem cells, embryonic stem cells, or induced pl...

    Authors: Soumya K. Kar, Jerry M. Wells, Esther D. Ellen, Marinus F. W. te Pas, Ole Madsen, Martien A. M. Groenen and Henri Woelders

    Citation: Veterinary Research 2021 52:43

    Content type: Review

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  44. Within the past decades, major progress has been accomplished in isolating germ/stem/pluripotent cells, in refining culture medium and conditions and in establishing 3-dimensional culture systems, towards deve...

    Authors: Guillaume Bourdon, Véronique Cadoret, Gilles Charpigny, Anne Couturier-Tarrade, Rozenn Dalbies-Tran, Maria-José Flores, Pascal Froment, Mariam Raliou, Karine Reynaud, Marie Saint-Dizier and Alice Jouneau

    Citation: Veterinary Research 2021 52:42

    Content type: Review

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  45. MicroRNAs (miRNAs) are short, non-coding RNAs, 21–23 nucleotides in length which are known to regulate biological processes that greatly impact immune system activity. The aim of the study was to compare the m...

    Authors: Emilia Bagnicka, Ewelina Kawecka-Grochocka, Klaudia Pawlina-Tyszko, Magdalena Zalewska, Aleksandra Kapusta, Ewa Kościuczuk, Sylwester Marczak and Tomasz Ząbek

    Citation: Veterinary Research 2021 52:41

    Content type: Research article

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  46. Leveraging artificial intelligence (AI) approaches in animal health (AH) makes it possible to address highly complex issues such as those encountered in quantitative and predictive epidemiology, animal/human p...

    Authors: Pauline Ezanno, Sébastien Picault, Gaël Beaunée, Xavier Bailly, Facundo Muñoz, Raphaël Duboz, Hervé Monod and Jean-François Guégan

    Citation: Veterinary Research 2021 52:40

    Content type: Review

    Published on:

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