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  1. PRRSV-1 virulent strains cause high fever, marked respiratory disease and severe lesions in lung and lymphoid organs. Regulated cell death (RCD), such as apoptosis, necroptosis and pyroptosis, is triggered by ...

    Authors: Jose María Sánchez-Carvajal, Inés Ruedas-Torres, Librado Carrasco, Francisco José Pallarés, Enric Mateu, Irene Magdalena Rodríguez-Gómez and Jaime Gómez-Laguna

    Citation: Veterinary Research 2021 52:12

    Content type: Research article

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  2. Infection with Mycobacterium avium subspecies paratuberculosis (MAP) is complex, but little is known about the role that natural killer (NK) cells play. In the present study, four bovine NK-lysin peptides were sy...

    Authors: Rohana P. Dassanayake, Taylor L. T. Wherry, Shollie M. Falkenberg, Timothy A. Reinhardt, Eduardo Casas and Judith R. Stabel

    Citation: Veterinary Research 2021 52:11

    Content type: Short report

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  3. Serotyping is the most common method to characterize field isolates of Actinobacillus (A.) pleuropneumoniae, the etiological agent of porcine pleuropneumonia. Based on serology, many farms seem to be infected and...

    Authors: Lukas Schuwerk, Doris Hoeltig, Karl-Heinz Waldmann, Peter Valentin-Weigand and Judith Rohde

    Citation: Veterinary Research 2021 52:10

    Content type: Research article

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  4. Novel duck reovirus (NDRV) causes severe economic losses to the duck industry, which is characterized by hemorrhagic spots and necrotic foci of the livers and spleens. DEAD-box helicase 1 (DDX1) plays a critic...

    Authors: Huihui Zhang, Xingdong Song, Tianxu Li, Jinchao Wang, Bin Xing, Xinyu Zhai, Jinjian Luo, Xiaofang Hu, Xiaolan Hou and Liangmeng Wei

    Citation: Veterinary Research 2021 52:9

    Content type: Research article

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  5. Since 2014, clade 2.3.4.4 has become the dominant epidemic branch of the Asian lineage H5 subtype highly pathogenic avian influenza virus (HPAIV) in southern and eastern China, while the H5N6 subtype is the mo...

    Authors: Ruyi Gao, Min Gu, Liwei Shi, Kaituo Liu, Xiuli Li, Xiaoquan Wang, Jiao Hu, Xiaowen Liu, Shunlin Hu, Sujuan Chen, Daxin Peng, Xinan Jiao and Xiufan Liu

    Citation: Veterinary Research 2021 52:8

    Content type: Research article

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  6. Elucidating virus-cell interactions is fundamental to understanding viral replication and identifying targets for therapeutic control of viral infection. The extracellular signal-regulated kinase (ERK) pathway...

    Authors: Huan Wang, Dingxiang Liu, Yingjie Sun, Chunchun Meng, Lei Tan, Cuiping Song, Xusheng Qiu, Weiwei Liu, Chan Ding and Liao Ying

    Citation: Veterinary Research 2021 52:7

    Content type: Research article

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  7. Inorganic pyrophosphatase (PPase) participates in energy cycle and plays a vital role in hydrolysis of inorganic pyrophosphate (PPi) into inorganic phosphate (Pi). The aim of this study was to investigate the ...

    Authors: Chen Xi Hu, Jie Zeng, Hui Nan Hao, Yang Xiu Yue Xu, Fang Liu, Ruo Dan Liu, Shao Rong Long, Zhong Quan Wang and Jing Cui

    Citation: Veterinary Research 2021 52:6

    Content type: Research article

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  8. Bovine respiratory diseases (BRD) are a major concern for the beef cattle industry, as beef calves overwhelmingly develop BRD symptoms during the first weeks after their arrival at fattening units. These cases...

    Authors: Thibaut Morel-Journel, Sébastien Assié, Elisabeta Vergu, Jean-Baptiste Mercier, Florence Bonnet-Beaugrand and Pauline Ezanno

    Citation: Veterinary Research 2021 52:5

    Content type: Research article

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  9. The transport of circovirus capsid protein into nucleus is essential for viral replication in infected cell. However, the role of nucleolar shuttle proteins during porcine circovirus 3 capsid protein (PCV3 Cap...

    Authors: Jianwei Zhou, Juan Li, Haimin Li, Ying Zhang, Weiren Dong, Yulan Jin, Yan Yan, Jinyan Gu and Jiyong Zhou

    Citation: Veterinary Research 2021 52:4

    Content type: Research article

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  10. Unlike the successful immunization of native H. contortus antigens that contributed to the realization of the first commercial vaccine Barbervax, not many studies revealed the encouraging protective efficacies of...

    Authors: Mingmin Lu, Xiaowei Tian, Yang Zhang, Wenjuan Wang, Ai-Ling Tian, Kalibixiati Aimulajiang, Lianrui Liu, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song and Xiangrui Li

    Citation: Veterinary Research 2021 52:3

    Content type: Research article

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  11. Porcine epidemic diarrhea (PED) is a coronavirus disease characterized by the rapid spread of severe diarrhea among pigs. PED virus (PEDV) infects and replicates mainly in the epithelial cells of the duodenum,...

    Authors: Yuto Suda, Ayako Miyazaki, Kohtaro Miyazawa, Tomoyuki Shibahara and Seiichi Ohashi

    Citation: Veterinary Research 2021 52:2

    Content type: Research article

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  12. Psoroptic mange is a common disease of livestock, caused by Psoroptes ovis. Compared to Holstein–Friesian (HF) cattle, the Belgian Blue (BB) cattle breed is highly susceptible to the infestation. However, the mec...

    Authors: Zhenzhen Chen, Edwin Claerebout, Koen Chiers, Mathilde Pas, Bart Pardon, Wouter van Mol, Stijn Casaert, Nathalie De Wilde, Luc Duchateau and Peter Geldhof

    Citation: Veterinary Research 2021 52:1

    Content type: Research article

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  13. This study focuses on the immunoregulatory effects of chicken TRIM25 on the replication of subgroup A of avian leukosis virus (ALV-A) and the MDA5-mediated type I interferon response. The ALV-A-SDAU09C1 strain...

    Authors: Jin-run Zhou, Jun-hong Liu, Hong-mei Li, Yue Zhao, Ziqiang Cheng, Yan-meng Hou and Hui-jun Guo

    Citation: Veterinary Research 2020 51:145

    Content type: Research article

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  14. One of the major bacterial infectious diseases in the poultry industry is avian pathogenic Escherichia coli (APEC), which causes colibacillosis in chickens. To develop a novel nucleic acid-free bacterial ghost (B...

    Authors: Safoura Soleymani, Amin Tavassoli, Gholamreza Hashemi Tabar, Gholam Ali Kalidari and Hesam Dehghani

    Citation: Veterinary Research 2020 51:144

    Content type: Research article

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  15. A recombinant fowl adenovirus (FAdV) fiber protein, derived from a FAdV-8a strain, was tested for its efficacy to protect chickens against inclusion body hepatitis (IBH). FAdV-E field isolates belonging to bot...

    Authors: Carlotta De Luca, Anna Schachner, Taniya Mitra, Sarah Heidl, Dieter Liebhart and Michael Hess

    Citation: Veterinary Research 2020 51:143

    Content type: Research article

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  16. Two functionally distinct isoforms of warm-temperature acclimation related 65-kDa protein (Wap65-1 and Wap65-2) with a role in the immune response are present in fish. To our knowledge, contrary to Wap65-1, Wa...

    Authors: Mariola A. Dietrich, Mikołaj Adamek, Verena Jung-Schroers, Krzysztof Rakus, Magdalena Chadzińska, Anna Hejmej, Piotr Hliwa, Barbara Bilińska, Halina Karol and Andrzej Ciereszko

    Citation: Veterinary Research 2020 51:142

    Content type: Research article

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  17. Revealing the multifocal mechanisms affecting cross-talk between Clostridium perfringens pathogenesis and the host response is an urgent need in the poultry industry. Herein, the activity of Cannabis sativa-deriv...

    Authors: Paweł Konieczka, Dominika Szkopek, Misza Kinsner, Bartosz Fotschki, Jerzy Juśkiewicz and Joanna Banach

    Citation: Veterinary Research 2020 51:141

    Content type: Research article

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  18. Pasteurella (P.) multocida is a zoonotic pathogen, which is able to cause respiratory disorder in different hosts. In cattle, P. multocida is an important microorganism involved in the bovine respiratory disease ...

    Authors: Ang Su, Jie Tong, Yuguang Fu, Sandy Müller, Yenehiwot Berhanu Weldearegay, Paul Becher, Peter Valentin-Weigand, Jochen Meens and Georg Herrler

    Citation: Veterinary Research 2020 51:140

    Content type: Research article

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  19. Trichinella spiralis serpin-type serine protease inhibitors (TsSPIs) are expressed in adult worms (AW), newborn larvae (NBL) and muscle larvae (ML) of T. spiralis, with the ML stage demonstrating the highest expr...

    Authors: Nana Yi, Pengcheng Yu, Lijia Wu, Zhaokun Liu, Jingzhe Guan, Chang Liu, Mingxu Liu and Yixin Lu

    Citation: Veterinary Research 2020 51:139

    Content type: Research article

    Published on:

  20. Dendritic cells (DCs) play a pivotal role to amplify antigen-specific immune responses. Antigens that sensitize T cells via antigen-presentation by DCs could enhance the capacity of host immunity to fight infe...

    Authors: Shakeel Ahmed Lakho, Muhammad Haseeb, Jianmei Huang, Zhang Yang, Muhammad Waqqas Hasan, Muhammad Tahir Aleem, Muhammad Ali-ul-Husnain Naqvi, Muhammad Ali Memon, XiaoKai Song, RuoFeng Yan, Lixin Xu and XiangRui Li

    Citation: Veterinary Research 2020 51:138

    Content type: Research article

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  21. Glaesserella parasuis is an important pathogen in swine production. It acts as a primary pathogen in systemic Glässer´s disease and as a secondary pathogen in Porcine Respiratory Disease Complex. In this study, a...

    Authors: Lukas Schuwerk, Doris Hoeltig, Karl-Heinz Waldmann, Katrin Strutzberg-Minder, Peter Valentin-Weigand and Judith Rohde

    Citation: Veterinary Research 2020 51:137

    Content type: Research article

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  22. Porcine epidemic diarrhea virus (PEDV) causes lethal diarrhea in suckling piglets, leading to severe economic losses worldwide. There is an urgent need to find new therapeutic methods to prevent and control PE...

    Authors: Pengcheng Wang, Juan Bai, Xuewei Liu, Mi Wang, Xianwei Wang and Ping Jiang

    Citation: Veterinary Research 2020 51:136

    Content type: Research article

    Published on:

  23. Duck enteritis virus (DEV) is a member of the Alphaherpesvirinae subfamily. The characteristics of some DEV genes have been reported. However, information regarding the DEV UL47 gene is limited. In this study, we...

    Authors: Tianqiong He, Mingshu Wang, Anchun Cheng, Qiao Yang, Renyong Jia, Ying Wu, Juan Huang, Shun Chen, Xin-Xin Zhao, Mafeng Liu, Dekang Zhu, Shaqiu Zhang, Xuming Ou, Sai Mao, Qun Gao, Di Sun…

    Citation: Veterinary Research 2020 51:135

    Content type: Research article

    Published on:

  24. Salmonid Rickettsial Septicaemia (SRS), caused by Piscirickettsia salmonis, is a severe bacterial disease in the Chilean salmon farming industry. Vaccines and antibiotics are the current strategies to fight SRS; ...

    Authors: Mario Caruffo, Dinka Mandakovic, Madelaine Mejías, Ignacio Chávez-Báez, Pablo Salgado, Daniela Ortiz, Liliana Montt, Javiera Pérez-Valenzuela, Francisca Vera-Tamargo, José Manuel Yánez, Jurij Wacyk and Rodrigo Pulgar

    Citation: Veterinary Research 2020 51:134

    Content type: Research article

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  25. Reticuloendotheliosis is an important immunosuppressive disease, associated with avian reticuloendotheliosis virus (REV) infection, and causes notable economic losses worldwide. Glycoprotein gp90 is an importa...

    Authors: Qing Pan, Jing Wang, Altaf Hussain, Yulong Gao, Hongyu Cui, Kai Li, Xiaole Qi, Changjun Liu, Yanping Zhang, Shide Zhang and Xiaomei Wang

    Citation: Veterinary Research 2020 51:133

    Content type: Research article

    Published on:

  26. MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression profiles in chicken dendritic cells infected with H9N2 avian in...

    Authors: Jing Yang, Xinmei Huang, Yuzhuo Liu, Dongmin Zhao, Kaikai Han, Lijiao Zhang, Yin Li and Qingtao Liu

    Citation: Veterinary Research 2020 51:132

    Content type: Short report

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  27. Cefquinome is administered in horses for the treatment of respiratory infection caused by Streptococcus equi subsp. zooepidemicus, and septicemia caused by Escherichia coli. However, there have been no attempts t...

    Authors: Dong-Ha Lee, Biruk Tesfaye Birhanu, Eon-Bee Lee, Seung-Jin Lee, Naila Boby, Yong-Soo Park and Seung-Chun Park

    Citation: Veterinary Research 2020 51:131

    Content type: Research article

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  28. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Insa Dammann, Wiebke M. Wemheuer, Arne Wrede, Wilhelm E. Wemheuer, Amely Campe, Jutta Petschenka, Ulf Schulze-Sturm, Uwe Hahmann, Claus P. Czerny, Pia Münster, Bertram Brenig, Lothar Kreienbrock, Christiane Herden and Walter J. Schulz-Schaeffer

    Citation: Veterinary Research 2020 51:130

    Content type: Correction

    Published on:

    The original article was published in Veterinary Research 2020 51:82

  29. Type 3 immunity encompasses innate and adaptive immune responses mediated by cells that produce the signature cytokines IL-17A and IL-17F. This class of effector immunity is particularly adept at controlling i...

    Authors: Pascal Rainard, Patricia Cunha, Rodrigo P. Martins, Florence B. Gilbert, Pierre Germon and Gilles Foucras

    Citation: Veterinary Research 2020 51:129

    Content type: Opinion

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  30. Porcine reproductive and respiratory syndrome virus (PRRSV) infection is the most important viral disease causing severe economic losses in the swine industry. However, mechanisms underlying gene expression co...

    Authors: Byeonghwi Lim, Sangwook Kim, Kyu-Sang Lim, Chang-Gi Jeong, Seung-Chai Kim, Sang-Myeong Lee, Choi-Kyu Park, Marinus F. W. te Pas, Haesu Gho, Tae-Hun Kim, Kyung-Tai Lee, Won-Il Kim and Jun-Mo Kim

    Citation: Veterinary Research 2020 51:128

    Content type: Research article

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  31. Zinc is the second trace element of living organisms after iron. Given its crucial importance, mammalian hosts restrict the bioavailability of Zinc ions (Zn2+) to bacterial pathogens. As a countermeasure, pathoge...

    Authors: Guomei Quan, Pengpeng Xia, Siqi Lian, Yunping Wu and Guoqiang Zhu

    Citation: Veterinary Research 2020 51:127

    Content type: Research article

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  32. Eggs produced by bisexual infected mature female worms (MF) of Schistosoma japonicum are important in the transmission of the parasite and responsible for the pathogenesis of schistosomiasis. The single-sex infec...

    Authors: Yu Han, Jintao Feng, Yuqi Ren, Luobin Wu, Hao Li, Jinming Liu and Yamei Jin

    Citation: Veterinary Research 2020 51:126

    Content type: Research article

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  33. The aim of this study was to investigate the biological characteristics and functions of a Trichinella spiralis serine proteinase (TsSerp) during larval invasion and development in the host. The full-length TsSer...

    Authors: Xin Yue, Xiang Yuan Sun, Fang Liu, Chen Xi Hu, Ying Bai, Qi Da Yang, Ruo Dan Liu, Xi Zhang, Jing Cui and Zhong Quan Wang

    Citation: Veterinary Research 2020 51:125

    Content type: Research article

    Published on:

  34. Many studies report age as a risk factor for BoHV-1 infection or seropositivity. However, it is unclear whether this pattern reflects true epidemiological causation or is a consequence of study design and othe...

    Authors: Jonas Brock, Martin Lange, Maria Guelbenzu-Gonzalo, Natascha Meunier, Ana Margarida Vaz, Jamie A. Tratalos, Peter Dittrich, Michael Gunn, Simon J. More, David Graham and Hans-Hermann Thulke

    Citation: Veterinary Research 2020 51:124

    Content type: Research article

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  35. Infectious coryza (IC), an upper respiratory tract disease affecting chickens, is caused by Avibacterium paragallinarum. The clinical manifestations of IC include nasal discharge, facial swelling, and lacrimation...

    Authors: Karla Lucía F. Alvarez, Astrid Poma-Acevedo and Manolo Fernández-Díaz

    Citation: Veterinary Research 2020 51:123

    Content type: Research article

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  36. Cathelicidins (CATHs) play an important role in the innate immune response against microbial infections. Among the four chicken cathelicidins, CATH-B1 is studied the least. In this study, the effect of CATH-B1...

    Authors: Lianci Peng, Maaike R. Scheenstra, Roel M. van Harten, Henk P. Haagsman and Edwin J. A. Veldhuizen

    Citation: Veterinary Research 2020 51:122

    Content type: Research article

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  37. M. bovis is one of the leading causes of respiratory disease and antimicrobial use in cattle. The pathogen is widespread in different cattle industries worldwide, but highest prevalence is found in the veal indus...

    Authors: Jade Bokma, Nick Vereecke, Koen De Bleecker, Jozefien Callens, Stefaan Ribbens, Hans Nauwynck, Freddy Haesebrouck, Sebastiaan Theuns, Filip Boyen and Bart Pardon

    Citation: Veterinary Research 2020 51:121

    Content type: Research article

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  38. Bromodomain-containing protein 2 (BRD2) is a nucleus-localized serine-threonine kinase that plays pivotal roles in the transcriptional control of diverse genes. In our previous study, the chicken BRD2 (chBRD2)...

    Authors: Zhiqiang Duan, Yifan Han, Lei Zhou, Chao Yuan, Yanbi Wang, Caiqin Zhao, Hong Tang and Jiaqi Chen

    Citation: Veterinary Research 2020 51:120

    Content type: Research article

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  39. Lesions of adiaspiromycosis, a respiratory disease affecting wild animals, have been found mainly in dead mammals and free-living mammals captured for surveillance. No report has described an investigation of ...

    Authors: Asuka Takeshige, Mie Nakano, Daisuke Kondoh, Yuma Tanaka, Akio Sekiya, Takashi Yaguchi, Hidefumi Furuoka and Takahito Toyotome

    Citation: Veterinary Research 2020 51:119

    Content type: Research article

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  40. Cyclic GMP-AMP (cGAMP) synthase (cGAS) is an intracellular sensor of cytoplasmic viral DNA created during virus infection, which subsequently activates the stimulator of interferon gene (STING)-dependent type ...

    Authors: Zongyi Bo, Yurun Miao, Rui Xi, Qiuping Zhong, Chenyi Bao, Huan Chen, Liumei Sun, Yingjuan Qian, Yong-Sam Jung and Jianjun Dai

    Citation: Veterinary Research 2020 51:118

    Content type: Research article

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  41. In 2016/2017, H5N8 highly pathogenic avian influenza (HPAI) virus of the Goose/Guangdong lineage spread from Asia to Europe, causing the biggest and most widespread HPAI epidemic on record in wild and domestic...

    Authors: Valentina Caliendo, Lonneke Leijten, Lineke Begeman, Marjolein J. Poen, Ron A. M. Fouchier, Nancy Beerens and Thijs Kuiken

    Citation: Veterinary Research 2020 51:117

    Content type: Research article

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  42. Biomedical research relies on the use of animal models, and the animals used in those models receive medical care, including antibiotics for brief periods of time to treat conditions such as dermatitis, fight ...

    Authors: Scott W. Korte, Rebecca A. Dorfmeyer, Craig L. Franklin and Aaron C. Ericsson

    Citation: Veterinary Research 2020 51:116

    Content type: Research article

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  43. Coccidiosis, caused by Eimeria species parasites, has long been recognised as an economically significant disease of chickens. As the global chicken population continues to grow, and its contribution to food secu...

    Authors: Damer P. Blake, Jolene Knox, Ben Dehaeck, Ben Huntington, Thilak Rathinam, Venu Ravipati, Simeon Ayoade, Will Gilbert, Ayotunde O. Adebambo, Isa Danladi Jatau, Muthusamy Raman, Daniel Parker, Jonathan Rushton and Fiona M. Tomley

    Citation: Veterinary Research 2020 51:115

    Content type: Research article

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  44. Erysipelas, a disease caused by Erysipelothrix rhusiopathiae (ER), is an increasing problem in laying hens housed in cage-free systems. This study aimed to monitor immune responses during ER infection of naïve ch...

    Authors: Eva Wattrang, Helena Eriksson, Tomas Jinnerot, Maria Persson, Elisabeth Bagge, Robert Söderlund, Mohammad Naghizadeh and Tina Sørensen Dalgaard

    Citation: Veterinary Research 2020 51:114

    Content type: Research article

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  45. Chickens are highly susceptible to highly pathogenic avian influenza viruses (HPAIVs). However, the severity of infection varies depending of the viral strain and the genetic background of the host. In this st...

    Authors: Raúl Sánchez-González, Antonio Ramis, Miquel Nofrarías, Nabil Wali, Rosa Valle, Mónica Pérez, Albert Perlas and Natàlia Majó

    Citation: Veterinary Research 2020 51:113

    Content type: Research article

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  46. To increase expression levels of the PCV2 Cap(d41) protein, novel baculovirus surface display vectors with multiple expression cassettes were constructed to create recombinant baculoviruses BacSC-Cap(d41), Bac...

    Authors: Ya-Yi Chen, Wei-Chen Yang, Yu-Kang Chang, Chi-Young Wang, Wei-Ru Huang, Jyun-Yi Li, Kuo-Pin Chuang, Hung-Yi Wu, Ching-Dong Chang, Brent L. Nielsen and Hung-Jen Liu

    Citation: Veterinary Research 2020 51:112

    Content type: Research article

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  47. In our previous studies, a novel T. spiralis peptidase (TsP) was identified among the excretory/secretory (ES) proteins of T. spiralis intestinal infective larvae (IIL) and T. spiralis at the adult worm (AW) stag...

    Authors: Jun Jun Lei, Yuan Yuan Hu, Fang Liu, Shu Wei Yan, Ruo Dan Liu, Shao Rong Long, Peng Jiang, Jing Cui and Zhong Quan Wang

    Citation: Veterinary Research 2020 51:111

    Content type: Research article

    Published on:

  48. Canine parvovirus (CPV) can cause acute and highly contagious bloody enteritis in dog. To obtain antibodies against CPV, hens were immunized with virus-like particles (VLP) of CPV-VP2. The IgY single chain fra...

    Authors: Shikun Ge, Long Xu, Ben Li, Fagang Zhong, Xiang Liu and Xiaoying Zhang

    Citation: Veterinary Research 2020 51:110

    Content type: Research article

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  49. Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species. Inc...

    Authors: Sonja Kittl, Thierry Francey, Isabelle Brodard, Francesco C. Origgi, Stéphanie Borel, Marie-Pierre Ryser-Degiorgis, Ariane Schweighauser and Joerg Jores

    Citation: Veterinary Research 2020 51:109

    Content type: Short report

    Published on:

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