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  1. Research Article

    Fecal shedding and tissue infections demonstrate transmission of Mycobacterium avium subsp. paratuberculosis in group-housed dairy calves

    Current Johne’s disease control programs primarily focus on decreasing transmission of Mycobacterium avium subsp. paratuberculosis (MAP) from infectious adult cows to susceptible calves. However, potential transm...

    Caroline S. Corbett, Jeroen De Buck, Karin Orsel and Herman W. Barkema

    Veterinary Research 2017 48:27

    Published on: 28 April 2017

  2. Opinion

    Mammary microbiota of dairy ruminants: fact or fiction?

    Explorations of how the complex microbial communities that inhabit different body sites might contribute to health and disease have prompted research on the ways the harmonious relationship between a host and ...

    Pascal Rainard

    Veterinary Research 2017 48:25

    Published on: 17 April 2017

  3. Research Article

    Phylodynamics of foot-and-mouth disease virus O/PanAsia in Vietnam 2010–2014

    Foot-and-mouth disease virus (FMDV) is endemic in Vietnam, a country that plays an important role in livestock trade within Southeast Asia. The large populations of FMDV-susceptible species in Vietnam are impo...

    Barbara Brito, Steven J. Pauszek, Michael Eschbaumer, Carolina Stenfeldt, Helena C. de Carvalho Ferreira, Le T. Vu, Nguyen T. Phuong, Bui H. Hoang, Nguyen D. Tho, Pham V. Dong, Phan Q. Minh, Ngo T. Long, Donald P. King, Nick J. Knowles, Do H. Dung, Luis L. Rodriguez…

    Veterinary Research 2017 48:24

    Published on: 13 April 2017

  4. Research Article

    Permissiveness of bovine epithelial cells from lung, intestine, placenta and udder for infection with Coxiella burnetii

    Ruminants are the main source of human infections with the obligate intracellular bacterium Coxiella (C.) burnetii. Infected animals shed high numbers of C. burnetii by milk, feces, and birth products. In goats, ...

    Katharina Sobotta, Katharina Bonkowski, Elisabeth Liebler-Tenorio, Pierre Germon, Pascal Rainard, Nina Hambruch, Christiane Pfarrer, Ilse D. Jacobsen and Christian Menge

    Veterinary Research 2017 48:23

    Published on: 12 April 2017

  5. Research Article

    Target organs for lymphocystis disease virus replication in gilthead seabream (Sparus aurata)

    The lymphocystis disease (LCD), the main viral pathology described in cultured gilthead seabream (Sparus aurata), is a self-limiting condition characterized by the appearance of hypertrophied fibroblasts (named l...

    Estefania J. Valverde, Juan J. Borrego, M. Carmen Sarasquete, Juan B. Ortiz-Delgado and Dolores Castro

    Veterinary Research 2017 48:21

    Published on: 11 April 2017

  6. Review

    Antimicrobial potential of bacteriocins in poultry and swine production

    The routine use of antibiotics in agriculture has contributed to an increase in drug-resistant bacterial pathogens in animals that can potentially be transmitted to humans. In 2000, the World Health Organizati...

    Amel Ben Lagha, Bruno Haas, Marcelo Gottschalk and Daniel Grenier

    Veterinary Research 2017 48:22

    Published on: 11 April 2017

  7. Research article

    Enhancing the toolbox to study IL-17A in cattle and sheep

    The development of methods to detect cytokine expression by T cell subsets in ruminants is fundamental to strategic development of new livestock vaccines for prevention of infectious diseases. It has been poss...

    Sean R. Wattegedera, Yolanda Corripio-Miyar, Yvonne Pang, David Frew, Tom N. McNeilly, Javier Palarea-Albaladejo, Colin J. McInnes, Jayne C. Hope, Elizabeth J. Glass and Gary Entrican

    Veterinary Research 2017 48:20

    Published on: 8 April 2017

  8. Research article

    Cytokine response to the RSV antigen delivered by dendritic cell-directed vaccination in congenic chicken lines

    Systems of antigen delivery into antigen-presenting cells represent an important novel strategy in chicken vaccine development. In this study, we verified the ability of Rous sarcoma virus (RSV) antigens fused...

    Jitka Mucksová, Jiří Plachý, Ondřej Staněk, Jiří Hejnar, Jiří Kalina, Barbora Benešová and Pavel Trefil

    Veterinary Research 2017 48:18

    Published on: 5 April 2017

  9. Short report

    Glyceraldehyde-3-phosphate dehydrogenase acts as an adhesin in Erysipelothrix rhusiopathiae adhesion to porcine endothelial cells and as a receptor in recruitment of host fibronectin and plasminogen

    Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. Previous studies suggested glyceraldehyde 3-phosphate dehydrogenase (GAPDH) plays a role in...

    Weifeng Zhu, Qiang Zhang, Jingtao Li, Yanmin Wei, Chengzhi Cai, Liang Liu, Zhongmin Xu and Meilin Jin

    Veterinary Research 2017 48:16

    Published on: 21 March 2017

  10. Research article

    CCL2 and CCL5 driven attraction of CD172a+ monocytic cells during an equine herpesvirus type 1 (EHV-1) infection in equine nasal mucosa and the impact of two migration inhibitors, rosiglitazone (RSG) and quinacrine (QC)

    Equine herpesvirus type 1 (EHV-1) causes respiratory disease, abortion and neurological disorders in horses. Besides epithelial cells, CD172a+ monocytic cells become infected with EHV-1 in the respiratory mucosa ...

    Jing Zhao, Katrien C. K. Poelaert, Jolien Van Cleemput and Hans J. Nauwynck

    Veterinary Research 2017 48:14

    Published on: 27 February 2017

  11. Research article

    Dynamic changes in bronchoalveolar macrophages and cytokines during infection of pigs with a highly or low pathogenic genotype 1 PRRSV strain

    Porcine reproductive and respiratory syndrome virus (PRRSV) replicates primarily in pulmonary alveolar macrophages (PAMs) and the resulting lung damage is influenced by strain virulence. To better understand t...

    Patricia Renson, Nicolas Rose, Mireille Le Dimna, Sophie Mahé, André Keranflec’h, Frédéric Paboeuf, Catherine Belloc, Marie-Frédérique Le Potier and Olivier Bourry

    Veterinary Research 2017 48:15

    Published on: 27 February 2017

  12. Research article

    Experimental infections of different carp strains with the carp edema virus (CEV) give insights into the infection biology of the virus and indicate possible solutions to problems caused by koi sleepy disease (KSD) in carp aquaculture

    Outbreaks of koi sleepy disease (KSD) caused by carp edema virus (CEV) may seriously affect populations of farmed common carp, one of the most important fish species for global food production. The present study ...

    Mikolaj Adamek, Anna Oschilewski, Peter Wohlsein, Verena Jung-Schroers, Felix Teitge, Andy Dawson, David Gela, Veronika Piackova, Martin Kocour, Jerzy Adamek, Sven M. Bergmann and Dieter Steinhagen

    Veterinary Research 2017 48:12

    Published on: 21 February 2017

  13. Research article

    Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis and metritis

    The heightened susceptibility to infectious diseases in postpartum dairy cows is often attributed to immune dysfunction associated with the transition period. However, the cell populations involved in this imm...

    Brianna Pomeroy, Anja Sipka, Jamal Hussen, Melanie Eger, Ynte Schukken and Hans-Joachim Schuberth

    Veterinary Research 2017 48:13

    Published on: 21 February 2017

  14. Research article

    Genotyping and investigating capsular polysaccharide synthesis gene loci of non-serotypeable Streptococcus suis isolated from diseased pigs in Canada

    Streptococcus suis (S. suis) is an important swine pathogen and an emerging zoonotic agent. Most clinical S. suis strains express capsular polysaccharides (CPS), which can be typed by ant...

    Han Zheng, Xiaotong Qiu, David Roy, Mariela Segura, Pengchen Du, Jianguo Xu and Marcelo Gottschalk

    Veterinary Research 2017 48:10

    Published on: 20 February 2017

  15. Review

    Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases: a review on bovine necro-haemorrhagic enteritis

    Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized...

    Evy Goossens, Bonnie R. Valgaeren, Bart Pardon, Freddy Haesebrouck, Richard Ducatelle, Piet R. Deprez and Filip Van Immerseel

    Veterinary Research 2017 48:9

    Published on: 16 February 2017

  16. Research article

    Betanodavirus-like particles enter host cells via clathrin-mediated endocytosis in a cholesterol-, pH- and cytoskeleton-dependent manner

    Betanodavirus, also referred to nervous necrosis virus (NNV), is the causative agent of the fatal disease, viral nervous necrosis and has brought significant economic losses in marine and freshwater cultured f...

    Runqing Huang, Guohua Zhu, Jing Zhang, Yuxiong Lai, Yu Xu, Jianguo He and Junfeng Xie

    Veterinary Research 2017 48:8

    Published on: 8 February 2017

  17. Short report

    The T160A hemagglutinin substitution affects not only receptor binding property but also transmissibility of H5N1 clade 2.3.4 avian influenza virus in guinea pigs

    We generated and characterized site-directed HA mutants on the genetic backbone of H5N1 clade 2.3.4 virus preferentially binding to α-2,3 receptors in order to identify the key determinants in hemagglutinin re...

    Min Gu, Qunhui Li, Ruyi Gao, Dongchang He, Yunpeng Xu, Haixu Xu, Lijun Xu, Xiaoquan Wang, Jiao Hu, Xiaowen Liu, Shunlin Hu, Daxin Peng, Xinan Jiao and Xiufan Liu

    Veterinary Research 2017 48:7

    Published on: 6 February 2017

  18. Research article

    Disruption of the M949_RS01915 gene changed the bacterial lipopolysaccharide pattern, pathogenicity and gene expression of Riemerella anatipestifer

    Riemerella anatipestifer is an important pathogen that causes septicemia anserum exsudativa in ducks. Lipopolysaccharide (LPS) is considered to be a major virulence factor of R. anatipest...

    Yafeng Dou, Xiaolan Wang, Guijing Yu, Shaohui Wang, Mingxing Tian, Jingjing Qi, Tao Li, Chan Ding and Shengqing Yu

    Veterinary Research 2017 48:6

    Published on: 6 February 2017

  19. Research article

    Correlating bacterial shedding with fecal corticosterone levels and serological responses from layer hens experimentally infected with Salmonella Typhimurium

    Salmonella Enteriditis and Salmonella Typhimurium are commonly isolated during egg-related outbreaks of salmonellosis and represent a significant international public health issue. In Aus...

    Pardeep Sharma, Vivek V. Pande, Talia S. Moyle, Andrea R. McWhorter and Kapil K. Chousalkar

    Veterinary Research 2017 48:5

    Published on: 6 February 2017

  20. Research article

    Frequency of Th17 cells correlates with the presence of lung lesions in pigs chronically infected with Actinobacillus pleuropneumoniae

    Porcine contagious pleuropneumonia caused by Actinobacillus pleuropneumoniae (APP) remains one of the major causes of poor growth performance and respiratory disease in pig herds. While the role of antibodies aga...

    Elena L. Sassu, Andrea Ladinig, Stephanie C. Talker, Maria Stadler, Christian Knecht, Heiko Stein, Janna Frömbling, Barbara Richter, Joachim Spergser, Monika Ehling-Schulz, Robert Graage, Isabel Hennig-Pauka and Wilhelm Gerner

    Veterinary Research 2017 48:4

    Published on: 6 February 2017

  21. Research article

    Escherichia coli O78 isolated from septicemic lambs shows high pathogenicity in a zebrafish model

    The pathogenicity of Escherichia coli O78 strain K46, originally isolated from an outbreak of septicemia in neonatal lambs, was investigated in zebrafish embryo and murine models of infection. Its biofilm potenti...

    Cecilie K. Kjelstrup, Amelia E. Barber, J. Paul Norton, Matthew A. Mulvey and Trine M. L’Abée-Lund

    Veterinary Research 2017 48:3

    Published on: 25 January 2017

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