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  1. Infectious diseases in livestock are well-known to infect multiple hosts and persist through a combination of within- and between-host transmission pathways. Uncertainty remains about the epidemic dynamics of ...

    Authors: Nicolas C. Cardenas, Abagael L. Sykes, Francisco P. N. Lopes and Gustavo Machado
    Citation: Veterinary Research 2022 53:14
  2. Porcine reproductive and respiratory syndrome virus (PRRSV) infection during late gestation negatively affects fetal development. The objective of this study was to identify the fetal organs most severely impa...

    Authors: Margaret K. Mulligan, Jocelyn E. Kleiman, Andrew C. Caldemeyer, John C. S. Harding and J. Alex Pasternak
    Citation: Veterinary Research 2022 53:13
  3. Recent publications suggest PCV2 vaccine-induced protection is superior when the vaccine and challenge are closely matched. PCV2’s evolutionary rate, propensity for recombination, and genotype shifting, all pr...

    Authors: Meggan Bandrick, Monica Balasch, Andrea Heinz, Lucas Taylor, Vickie King, Jeri Toepfer and Dennis Foss
    Citation: Veterinary Research 2022 53:12
  4. In late 2015, an epizootic of Highly Pathogenic Avian Influenza (H5Nx) was registered in Southwestern France, including more than 70 outbreaks in commercial poultry flocks. Phylogenetic analyses suggested loca...

    Authors: Nicolas Gaide, Marie-Noëlle Lucas, Mattias Delpont, Guillaume Croville, Kim M. Bouwman, Andreas Papanikolaou, Roosmarijn van der Woude, Iwan A. Gagarinov, Geert-Jan Boons, Robert P. De Vries, Romain Volmer, Angélique Teillaud, Timothée Vergne, Céline Bleuart, Guillaume Le Loc’h, Maxence Delverdier…
    Citation: Veterinary Research 2022 53:11
  5. Cell death and inflammation are intimately linked during mastitis due to Staphylococcus aureus (S. aureus). Pyroptosis, a programmed necrosis triggered by gasdermin protein family, often occurs after inflammatory...

    Authors: Xiaozhou Wang, Mingchao Liu, Na Geng, Yongzhen Du, Zhaoming Li, Xin Gao, Bo Han, Jianzhu Liu and Yongxia Liu
    Citation: Veterinary Research 2022 53:10
  6. The zoonotic pathogen Salmonella enterica serotype Enteritidis (SE) causes severe disease in young chickens. Restriction on antibiotic use requires alternative SE control strategies such as nutritional solutions ...

    Authors: Nathalie Meijerink, Jean E. de Oliveira, Daphne A. van Haarlem, David M. Lamot, Francisca C. Velkers, Hauke Smidt, J. Arjan Stegeman, Victor P. M. G. Rutten and Christine A. Jansen
    Citation: Veterinary Research 2022 53:9
  7. Cystic Echinococcosis (CE), a zoonotic parasitic disease, is caused by the cestode Echinococcus granulosus sensu lato. CE inflicts severe damage in cattle, sheep, and human hosts worldwide. Fertile CE cysts are c...

    Authors: Ismael Pereira, Christian Hidalgo, Caroll Stoore, María Soledad Baquedano, Carolina Cabezas, Macarena Bastías, Aníbal Riveros, Claudio Meneses, Martín Cancela, Henrique Bunselmeyer Ferreira, Leonardo Sáenz and Rodolfo Paredes
    Citation: Veterinary Research 2022 53:8
  8. The type I interferon (IFN-I) signaling pathway is an important part of the innate immune response and plays a vital role in controlling and eliminating pathogens. African swine fever virus (ASFV) encodes vari...

    Authors: Kaidian Yang, Ying Xue, Hui Niu, Chunwei Shi, Mingyang Cheng, Jianzhong Wang, Boshi Zou, Junhong Wang, Tianming Niu, Meiying Bao, Wentao Yang, Dandan Zhao, Yanlong Jiang, Guilian Yang, Yan Zeng, Xin Cao…
    Citation: Veterinary Research 2022 53:7
  9. Dihydromyricetin (DHM), a flavonoid in vine tea, has many pharmacological activities, including anti-inflammatory and antibacterial effects. Lipopolysaccharide is the key inducer of inflammation in avian patho...

    Authors: Chenxi Shi, Jiaqi Wang, Ruichen Zhang, Muhammad Ishfaq, Ying Li, Ruihui Zhang, Chuanbiao Si, Rui Li, Changwen Li and Fangping Liu
    Citation: Veterinary Research 2022 53:6
  10. In recent years, Klebsiella pneumoniae (KP) has caused disease outbreaks in different animals, resulting in serious economic losses and biosafety concerns. Considering the broad antibiotic resistance of KP, vacci...

    Authors: Gaowei Hu, Xue Chen, Wenhui Chu, Zhe Ma, Yingjie Miao, Xi Luo and Yongqian Fu
    Citation: Veterinary Research 2022 53:5
  11. Bovine respiratory disease (BRD), as one of the most common and costly diseases in the beef cattle industry, has significant adverse impacts on global food security and the economic stability of the industry. ...

    Authors: Jianmin Chai, Sarah F. Capik, Beth Kegley, John T. Richeson, Jeremy G. Powell and Jiangchao Zhao
    Citation: Veterinary Research 2022 53:4
  12. Trueperella pyogenes (T. pyogenes) is an opportunistic pathogen associated with a variety of diseases in many domestic animals. Therapeutic treatment options for T. pyogenes infections are becoming limited due to...

    Authors: Yuru Guo, Chengcheng Huang, Hongyu Su, Zehui Zhang, Menghan Chen, Ruxia Wang, Dexian Zhang, Luyao Zhang and Mingchun Liu
    Citation: Veterinary Research 2022 53:3
  13. The current investigation aimed at characterizing the cause of multiple disease outbreaks in the same broiler production unit during a course of 18 months. The outbreaks had mortality rates of up to 22%. Escheric...

    Authors: Anders Miki Bojesen, Umran Ahmed, Hanne Skaarup and Carmen Espinosa-Gongora
    Citation: Veterinary Research 2022 53:2
  14. To understand the differences in immune responses between early feathering (EF) and late feathering (LF) chickens after infection with avian leukosis virus, subgroup J (ALV-J), we monitored the levels of prola...

    Authors: Guodong Mo, Bowen Hu, Qihong Zhang, Zhuohao Ruan, Wangyu Li, Jiaying Liang, Yizi Shen, Zhixin Mo, Zihao Zhang, Zhuyue Wu, Meiqing Shi and Xiquan Zhang
    Citation: Veterinary Research 2022 53:1
  15. Viruses have evolved multiple strategies to manipulate their host’s translational machinery for the synthesis of viral proteins. A common viral target is the alpha subunit of eukaryotic initiation factor 2 (eI...

    Authors: Ting Zhu, Xueli Jiang, Hangkuo Xin, Xiaohui Zheng, Xiaonuan Xue, Ji-Long Chen and Baomin Qi
    Citation: Veterinary Research 2021 52:148
  16. The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are viral entry proteins and are recognized as the major virulence determinants. Previously, a lentogenic NDV viru...

    Authors: Xi Chen, Yanqing Jia, Ning Wei, Chao Ye, Huafang Hao, Sa Xiao, Xinglong Wang, Haijin Liu and Zengqi Yang
    Citation: Veterinary Research 2021 52:147
  17. Gram-negative bacteria are known to subvert eukaryotic cell physiological mechanisms using a wide array of virulence factors, among which the type three-secretion system (T3SS) is often one of the most importa...

    Authors: Hadis Rahmatelahi, Mansour El-Matbouli and Simon Menanteau-Ledouble
    Citation: Veterinary Research 2021 52:146
  18. Streptococcus suis is a zoonotic pathogen of swine involved in arthritis, polyserositis, and meningitis. Colonization of piglets by S. suis is very common and occurs early in life. The clinical outcome of infecti...

    Authors: Carlos Neila-Ibáñez, Louise Brogaard, Lola Pailler-García, Jorge Martínez, Joaquim Segalés, Mariela Segura, Peter M. H. Heegaard and Virginia Aragon
    Citation: Veterinary Research 2021 52:145
  19. Emergence of bovine mastitis caused by Prototheca algae is the impetus to better understand these infections. Both P. bovis and P. ciferrii belong to Prototheca algae, but they differ in their pathogenicity to in...

    Authors: Wenpeng Zhao, Fumeng He, Herman W. Barkema, Siyu Xu, Jian Gao, Gang Liu, Zhaoju Deng, Muhammad Shahid, Yuxiang Shi, John P. Kastelic and Bo Han
    Citation: Veterinary Research 2021 52:144
  20. Haemonchus contortus is a parasitic nematode of ruminants which causes significant losses to many farmers worldwide. Since the drugs currently in use for the treatment of haemonchosis are losing their effectivene...

    Authors: Markéta Zajíčková, Lukáš Prchal, Martina Navrátilová, Nikola Vodvárková, Petra Matoušková, Ivan Vokřál, Linh Thuy Nguyen and Lenka Skálová
    Citation: Veterinary Research 2021 52:143
  21. The intestinal epithelium plays a variety of roles including providing an effective physical barrier and innate immune protection against infection. Two-dimensional models of the intestinal epithelium, 2D ente...

    Authors: Brigid Orr, Kate Sutton, Sonja Christian, Tessa Nash, Helle Niemann, Lone Lind Hansen, Mike J. McGrew, Stina Rikke Jensen and Lonneke Vervelde
    Citation: Veterinary Research 2021 52:142
  22. Chlamydia psittaci was considered the predominant chlamydial species in poultry until Chlamydia gallinacea was discovered in 2009. C. psittaci is a zoonotic obligate intracellular bacterium reported in more than ...

    Authors: Marloes Heijne, Jeanet van der Goot, Herma Buys, Annemieke Dinkla, Hendrik Jan Roest, Lucien van Keulen and Ad Koets
    Citation: Veterinary Research 2021 52:141
  23. QseC, a histidine sensor kinase of the QseBC two-component system, acts as a global regulator of bacterial stress resistance, biofilm formation, and virulence. The function of QseC in some bacteria is well und...

    Authors: Yang Yang, Pei Hu, Lixu Gao, Xiang Yuan, Philip R. Hardwidge, Tian Li, Pan Li, Fang He, Yuanyi Peng and Nengzhang Li
    Citation: Veterinary Research 2021 52:140
  24. Chicken immune responses to infectious bronchitis virus (IBV) vaccination can depend on route of administration, vaccine strain and bird age. Typically for layer chickens, IBV vaccinations are administered by ...

    Authors: Mohammed Al-Rasheed, Christopher Ball and Kannan Ganapathy
    Citation: Veterinary Research 2021 52:139
  25. In this study, we investigated the role of heat shock protein 70 (HSP70) in porcine epidemic diarrhoea virus (PEDV) replication. We found that PEDV infection induced strong HSP70 overexpression in the very ear...

    Authors: Jae-Yeon Park, Jihoon Ryu, Jung-Eun Park, Eui-Ju Hong and Hyun-Jin Shin
    Citation: Veterinary Research 2021 52:138
  26. Although extensive research has been performed on bovine non-aureus staphylococci (NAS), several aspects such as bacteria-host interaction remain largely unstudied. Moreover, only a few mastitis pathogen challeng...

    Authors: Lisa Beuckelaere, Anneleen De Visscher, Fernando Nogueira Souza, Evelyne Meyer, Freddy Haesebrouck, Sofie Piepers and Sarne De Vliegher
    Citation: Veterinary Research 2021 52:137
  27. Glaesserella parasuis (G. parasuis) is a commensal bacterium in the upper respiratory tract of pigs that can also cause the swine Glässer disease, which induces an intensive inflammatory response and results in s...

    Authors: Qing Wang, Xiaojing Chang, Mingxing Liu, Qi Lu, Meng Zhu, Huixing Lin and Hongjie Fan
    Citation: Veterinary Research 2021 52:135
  28. A type of monophasic group B Salmonella enterica with the antigenic formula 4,12:a:- (“Fulica-like”) has been described as associated with harbour porpoises (Phocoena phocoena), most frequently recovered from lun...

    Authors: Arnar K. S. Sandholt, Aleksija Neimanis, Anna Roos, Jenny Eriksson and Robert Söderlund
    Citation: Veterinary Research 2021 52:134
  29. Streptococcus suis is an important swine pathogen responsible for economic losses to the swine industry worldwide. There is no effective commercial vaccine against S. suis. The use of autogenous (“bacterin”) vacc...

    Authors: Milan R. Obradovic, Lorelei Corsaut, Dominic Dolbec, Marcelo Gottschalk and Mariela Segura
    Citation: Veterinary Research 2021 52:133
  30. The study aim was to determine the expression of genes potentially related to chronic mastitis at the mRNA and protein levels, viz. chemokine C–C motif receptor 1 (CCR1), C–C motif chemokine ligand 2 (CCL2), C–C ...

    Authors: Ewelina Kawecka-Grochocka, Magdalena Zalewska, Magdalena Rzewuska, Ewa Kościuczuk, Tomasz Ząbek, Tomasz Sakowski, Sylwester Marczak and Emilia Bagnicka
    Citation: Veterinary Research 2021 52:132
  31. Piscine orthoreovirus-1 (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). However, it has been shown that PRV-1 variants differ in their abil...

    Authors: Nina A. Vatne, Marit Stormoen, Morten Lund, Magnus Devold, Espen Rimstad and Øystein Wessel
    Citation: Veterinary Research 2021 52:131
  32. Mycoplasma species are the smallest prokaryotes capable of self-replication. To investigate Mycoplasma induced autophagy in mammalian cells, Mycoplasma bovis (M. bovis) and bovine mammary epithelial cells (bMEC) ...

    Authors: Yang Liu, Zhaoju Deng, Siyu Xu, Gang Liu, Yushan Lin, Sohrab Khan, Jian Gao, Weijie Qu, John P. Kastelic and Bo Han
    Citation: Veterinary Research 2021 52:130
  33. To date, chronic wasting disease (CWD) is the most infectious form of prion disease affecting several captive, free ranging and wild cervid species. Responsible for marked population declines in North America,...

    Authors: Katayoun Moazami-Goudarzi, Olivier Andréoletti, Jean-Luc Vilotte and Vincent Béringue
    Citation: Veterinary Research 2021 52:128
  34. Mammary pathogenic Escherichia coli (MPEC) is an important causative agent of mastitis in dairy cows that results in reduced milk quality and production, and is responsible for severe economic losses in the dairy...

    Authors: Hui Wang, Fei Shang, Jiawei Shen, Jingyi Xu, Xiaolin Chen, Jingtian Ni, Lumin Yu and Ting Xue
    Citation: Veterinary Research 2021 52:127
  35. This work modifies a loop-mediated isothermal amplification (LAMP) assay to detect the bovine respiratory disease (BRD) bacterial pathogens Pasteurella multocida, Mannheimia haemolytica, and Histophilus somni in ...

    Authors: Ana Pascual-Garrigos, Murali Kannan Maruthamuthu, Aaron Ault, Josiah Levi Davidson, Grigorii Rudakov, Deepti Pillai, Jennifer Koziol, Jon P. Schoonmaker, Timothy Johnson and Mohit S. Verma
    Citation: Veterinary Research 2021 52:126
  36. Efficient in vivo delivery of a CRISPR/Cas9 plasmid is of paramount importance for effective therapy. Here, we investigated the usability of Salmonella as a plasmid carrier for in vivo therapy against virus-induc...

    Authors: Amal Senevirathne, Chamith Hewawaduge and John Hwa Lee
    Citation: Veterinary Research 2021 52:125
  37. The parasitic gastrointestinal nematode Haemonchus contortus causes serious economic losses to agriculture due to infection and disease in small ruminant livestock. The development of new therapies requires appro...

    Authors: Linh Thuy Nguyen, Markéta Zajíčková, Eva Mašátová, Petra Matoušková and Lenka Skálová
    Citation: Veterinary Research 2021 52:124
  38. Salmonella enterica ssp. enterica serovars Enteritidis (SE) and Gallinarum (SG) cause different diseases in chickens. However, both are able to reach the blood stream where heterophils and monocytes are potential...

    Authors: Sravya Sreekantapuram, Christian Berens, Stefanie A. Barth, Ulrich Methner and Angela Berndt
    Citation: Veterinary Research 2021 52:123
  39. Mastitis is a complex inflammatory disease caused by pathogenic infection of mammary tissue in dairy cows. The molecular mechanism behind its occurrence, development, and regulation consists of a multi-gene ne...

    Authors: Zhuo-Ma Luoreng, Da-Wei Wei and Xing-Ping Wang
    Citation: Veterinary Research 2021 52:122

    The Correction to this article has been published in Veterinary Research 2021 52:136

  40. The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic is causing a global crisis. It is still unresolved. Although many therapies and vaccines are being studied, they are still in their inf...

    Authors: Myeon-Sik Yang, Byung Kwan Oh, Daram Yang, Eun Young Oh, Yeonhwa Kim, Kyung Won Kang, Chae Woong Lim, Gou Young Koh, Sang-Myeong Lee and Bumseok Kim
    Citation: Veterinary Research 2021 52:121
  41. Gyrovirus 3 (GyV3), the third novel emerging species of the genus Gyrovirus of the Anelloviridae family, has been described in multiple hosts. Epidemiologically, there are suggestions that GyV3 is associated with...

    Authors: Gen Li, Defang Zhou, Manda Zhao, Qing Liu, Xiaojing Hao, Tianxing Yan, Shiyu Yuan, Shicheng Zhang and Ziqiang Cheng
    Citation: Veterinary Research 2021 52:120
  42. Congenital avian leukosis virus subgroup J (ALV-J) infection can induce persistent immunotolerance in chicken, however, the underlying mechanism remains unclear. Here, we demonstrate that congenital ALV-J infe...

    Authors: Shuhai He, Gaoying Zheng, Defang Zhou, Li Huang, Jianguo Dong and Ziqiang Cheng
    Citation: Veterinary Research 2021 52:119
  43. Escherichia coli (E. coli) O157:H7 bacterial infection causes severe disease in mammals and results in substantial economic losses worldwide. Due to the development of antibiotic resistance, bacteriophage (phage)...

    Authors: Hanjie Yin, Jing Li, Haosheng Huang, Yuxin Wang, Xinjie Qian, Jianluan Ren, Feng Xue, Jianjun Dai and Fang Tang
    Citation: Veterinary Research 2021 52:118
  44. Edwardsiella tarda is a facultative intracellular pathogen in humans and animals. The Gram-negative bacterium is widely considered a potentially important bacterial pathogen. Adaptation to acid stress is importan...

    Authors: Chunmei Du, Xiaoping Huo, Hanjie Gu, Dongmei Wu and Yonghua Hu
    Citation: Veterinary Research 2021 52:117
  45. The management of infectious diseases in wildlife reservoirs is challenging and faces several limitations. However, detailed knowledge of host–pathogen systems often reveal heterogeneity among the hosts’ contr...

    Authors: Sébastien Lambert, Anne Thébault, Sophie Rossi, Pascal Marchand, Elodie Petit, Carole Toïgo and Emmanuelle Gilot-Fromont
    Citation: Veterinary Research 2021 52:116
  46. The spread of chronic wasting disease (CWD) during the last six decades has resulted in cervid populations of North America where CWD has become enzootic. This insidious disease has also been reported in wild ...

    Authors: Alicia Otero, Camilo Duque Velásquez, Judd Aiken and Debbie McKenzie
    Citation: Veterinary Research 2021 52:115
  47. Biofilm formation is a significant virulence factor in Staphylococcus (S.) aureus strains causing subclinical mastitis in dairy cows. A role of environmental signals and communication systems in biofilm developme...

    Authors: Bruno Toledo-Silva, Fernando N. de Souza, Kristien Mertens, Sofie Piepers, Freddy Haesebrouck and Sarne De Vliegher
    Citation: Veterinary Research 2021 52:114
  48. The aim of this study was to investigate the biological properties of a novel gut-specific cysteine protease in Trichinella spiralis (TsGSCP) and its role in larval intrusion, development and fecundity. TsGSCP ha...

    Authors: Yuan Yuan Hu, Ru Zhang, Shu Wei Yan, Wen Wen Yue, Jia Hang Zhang, Ruo Dan Liu, Shao Rong Long, Jing Cui and Zhong Quan Wang
    Citation: Veterinary Research 2021 52:113

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