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  1. GtxA, a leukotoxic RTX-toxin, has been proposed a main virulence factor of Gallibacterium anatis. To evaluate the impact of GtxA during infection, we experimentally infected laying hens with a G. anatis wild-type...

    Authors: Bo Tang, Susanne E. Pors, Bodil M. Kristensen, Ragnhild Bager J. Skjerning, Rikke H. Olsen and Anders M. Bojesen
    Citation: Veterinary Research 2020 51:40
    Content type: Research article Published on:

  2. Trichinellosis is an important food-borne parasitic zoonosis throughout the world. At present, the mechanisms of Trichinella spiralis infection remain unclear. Acquiring detailed information on the host-Trichinel...

    Authors: Xiao Han Ma, Hui Jun Ren, Ruo Yu Peng, Yi Li and Liang Ming
    Citation: Veterinary Research 2020 51:39
    Content type: Research article Published on:

  3. Rhodococcus equi is an intracellular veterinary pathogen that is becoming resistant to current antibiotherapy. Genes involved in preserving redox homeostasis could be promising targets for the development of nove...

    Authors: Álvaro Mourenza, Cristina Collado, Natalia Bravo-Santano, José A. Gil, Luís M. Mateos and Michal Letek
    Citation: Veterinary Research 2020 51:38
    Content type: Short report Published on:

  4. Chitosan nanoparticles (CNPs) represent an efficient vaccination tool to deliver immunogenic antigens to the antigen-presenting cells (APCs), which subsequently stimulate protective immune responses against in...

    Authors: Irshad Ahmed Hajam, Amal Senevirathne, Chamit Hewawaduge, Jehyoung Kim and John Hwa Lee
    Citation: Veterinary Research 2020 51:37
    Content type: Research article Published on:

  5. Mannheimia haemolytica serotype A2 is the principal cause of pneumonic mannheimiosis in ovine and caprine livestock; this disease is a consequence of immune suppression caused by stress and associated viruses and...

    Authors: Christian Avalos-Gómez, Magda Reyes-López, Gerardo Ramírez-Rico, Efrén Díaz-Aparicio, Edgar Zenteno, Cynthia González-Ruiz and Mireya de la Garza
    Citation: Veterinary Research 2020 51:36
    Content type: Research article Published on:

  6. Akkermansia muciniphila, a novel mucin-degrading bacterium, has been demonstrated to prevent the development of obesity and related complications. However, whether it can protect poultry from intestinal mucosal d...

    Authors: Linda Zhu, Xiaoxi Lu, Li Liu, Josef Voglmeir, Xiang Zhong and Qinghua Yu
    Citation: Veterinary Research 2020 51:34
    Content type: Research article Published on:

  7. Fasciola hepatica has been shown to have a high capacity for immunomodulation of the host response, making the development of protective vaccines extremely difficult. One of these immunomodulation mechanisms is t...

    Authors: María Teresa Ruiz-Campillo, Verónica Molina-Hernández, María José Bautista, Isabel L. Pacheco, Rafael Zafra, Leandro Buffoni, Francisco Javier Martínez-Moreno, Alvaro Martínez-Moreno and José Pérez
    Citation: Veterinary Research 2020 51:33
    Content type: Research article Published on:

  8. The presence of non-aureus staphylococci (NAS) in bovine rectal feces has recently been described. Similar to other mastitis causing pathogens, shedding of NAS in the environment could result in intramammary i...

    Authors: Ameline Wuytack, Anneleen De Visscher, Sofie Piepers, Freddy Haesebrouck and Sarne De Vliegher
    Citation: Veterinary Research 2020 51:32
    Content type: Research article Published on:

  9. Porcine circovirus type 2 (PCV2) is considered as the primary pathogen of porcine circovirus-associated disease (PCVAD), which results in significant economic losses worldwide. Clinically, PCV2 often causes di...

    Authors: Qing Wang, Hong Zhou, Huixing Lin, Zhe Ma and Hongjie Fan
    Citation: Veterinary Research 2020 51:31
    Content type: Research article Published on:

  10. Echinococcosis is a zoonotic disease caused by cestode species of the genus Echinococcus, which demonstrates considerable medical and veterinary concerns. The development of novel drugs for echinococcosis treatme...

    Authors: Qi Xin, Miaomiao Yuan, Huanping Li, Xiaoxia Song, Jun Lu and Tao Jing
    Citation: Veterinary Research 2020 51:29
    Content type: Short report Published on:

  11. The pore-forming protein epsilon toxin (Etx) from Clostridium perfringens produces acute perivascular edema affecting several organs, especially the brain and lungs. Despite the toxin evident effect on microvascu...

    Authors: Jonatan Dorca-Arévalo, Eduard Dorca, Benjamín Torrejón-Escribano, Marta Blanch, Mireia Martín-Satué and Juan Blasi
    Citation: Veterinary Research 2020 51:27
    Content type: Research article Published on:

  12. Probiotic pretreatment is an effective non-antibiotic strategy for preventing or controlling Salmonella infections. We found that Lactobacillus johnsonii L531, isolated from the colon of a clinically healthy wean...

    Authors: Gui-Yan Yang, Bing Xia, Jin-Hui Su, Ting He, Xiao Liu, Liang Guo, Shuai Zhang, Yao-Hong Zhu and Jiu-Feng Wang
    Citation: Veterinary Research 2020 51:26
    Content type: Research article Published on:

  13. Marek’s disease (MD) is a major disease of chickens induced by Marek’s disease virus (MDV) associated to lethal lymphomas. Current MD vaccines protect against lymphomas, but fail to prevent infection and shedd...

    Authors: Sylvie Rémy, Gilles Le Pape, David Gourichon, Yannick Gardin and Caroline Denesvre
    Citation: Veterinary Research 2020 51:24
    Content type: Research article Published on:

  14. Interferons (IFNs) induce the expression of interferon-stimulated genes (ISGs) for defense against numerous viral infections, including classical swine fever virus (CSFV). However, the mechanisms underlying th...

    Authors: Cheng Li, Yifan Wang, Hongqing Zheng, Wang Dong, Huifang Lv, Jihui Lin, Kangkang Guo and Yanming Zhang
    Citation: Veterinary Research 2020 51:22
    Content type: Research article Published on:

  15. Sialoadhesin (Sn) and CD163 have been recognized as two important mediators for porcine reproductive and respiratory syndrome virus (PRRSV) in host macrophages. Recently, it has been demonstrated that the high...

    Authors: Dayoung Oh, Jiexiong Xie, Nathalie Vanderheijden and Hans J. Nauwynck
    Citation: Veterinary Research 2020 51:21
    Content type: Research article Published on:

  16. Non-structural protein 1 (NS1) of influenza virus is a multifunctional protein that plays an important role in virus replication and virulence. In this study, an acetylation modification was identified at the ...

    Authors: Jingjiao Ma, Rujuan Wu, Guanlong Xu, Yuqiang Cheng, Zhaofei Wang, Heng’an Wang, Yaxian Yan, Jinxiang Li and Jianhe Sun
    Citation: Veterinary Research 2020 51:20
    Content type: Research article Published on:

  17. Marek’s disease (MD) is a contagious disease of domestic chickens caused by MD viruses. MD has been controlled primarily by vaccinations, yet sporadic outbreaks of MD take place worldwide. Commonly used MD vac...

    Authors: Lei Zhang, Chen Zhu, Mohammad Heidari, Kunzhe Dong, Shuang Chang, Qingmei Xie and Huanmin Zhang
    Citation: Veterinary Research 2020 51:19
    Content type: Research article Published on:

  18. Porcine reproductive and respiratory syndrome virus (PRRSV) is a significant threat to the global swine industry. Porcine sialoadhesin (poSn) has been previously shown to mediate PRRSV attachment and internali...

    Authors: Yingqi Liu, Rui Li, Songlin Qiao, Xin-xin Chen, Ruiguang Deng and Gaiping Zhang
    Citation: Veterinary Research 2020 51:18
    Content type: Research article Published on:

  19. Trichinellosis, which is caused by Trichinella spiralis (T. spiralis), is a serious zoonosis. Pigs play an important role in the transmission of human trichinellosis. Characterizing the immune response to T. spir...

    Authors: Nan Wang, Xue Bai, Bin Tang, Yong Yang, Xuelin Wang, Hongfei Zhu, Xuenong Luo, Hongbin Yan, Hong Jia, Mingyuan Liu and Xiaolei Liu
    Citation: Veterinary Research 2020 51:17
    Content type: Research article Published on:

  20. Bovine digital dermatitis (DD) is an important infectious cause of cattle lameness worldwide that has become increasingly prevalent in New Zealand pastoral dairy herds. In this study, a simplified DD scoring s...

    Authors: D. Aaron Yang, Richard A. Laven, Kristina R. Müller and M. Carolyn Gates
    Citation: Veterinary Research 2020 51:16
    Content type: Research article Published on:

  21. Guanylate-binding proteins (GBP1 and GBP5) are known to be important for host resistance against porcine reproductive and respiratory syndrome virus (PRRSV) infection. In this study, the effects of polymorphis...

    Authors: Amina Khatun, Salik Nazki, Chang-Gi Jeong, Suna Gu, Sameer ul Salam Mattoo, Sim-In Lee, Myun-Sik Yang, Byeonghwi Lim, Kwan-Suk Kim, Bumseok Kim, Kyoung-Tae Lee, Choi-Kyu Park, Sang-Myeong Lee and Won-Il Kim
    Citation: Veterinary Research 2020 51:14
    Content type: Research article Published on:

  22. In the original publication of this article [1], the corresponding author points out Pilar M. Muñoz and Raquel Conde‑Alvarez contributed equally to this work.

    Authors: Beatriz Aragón‑Aranda, María Jesús de Miguel, Estrella Martinez‑Gomez, Amaia Zuñiga‑Ripa, Miriam Salvador‑Bescós, Ignacio Moriyón, Maite Iriarte, Pilar M. Muñoz and Raquel Conde‑Alvarez
    Citation: Veterinary Research 2020 51:13
    Content type: Correction Published on:

    The original article was published in Veterinary Research 2019 50:95

  23. High-mobility group box 1 protein (HMGB1) shows endogenous damage-associated molecular patterns (DAMPs) and is also an early warning protein that activates the body’s innate immune system. Here, the full-lengt...

    Authors: Xiaolan Hou, Gen Liu, Huihui Zhang, Xiaofang Hu, Xinyue Zhang, Fei Han, Huizhen Cui, Jinjian Luo, Ru Guo, Rong Li, Ning Li and Liangmeng Wei
    Citation: Veterinary Research 2020 51:12
    Content type: Research article Published on:

  24. Staphylococcal mastitis is a major health problem in humans and livestock that leads to economic loss running in millions. This process is currently one of the main reasons for culling adult rabbit does. Surpr...

    Authors: Mariola Penadés, David Viana, Ana García-Quirós, Asunción Muñoz-Silvestre, Elena Moreno-Grua, Sara Pérez-Fuentes, Juan José Pascual, Juan M. Corpa and Laura Selva
    Citation: Veterinary Research 2020 51:11
    Content type: Research article Published on:

  25. With the emergence of highly pathogenic variant strains, porcine epidemic diarrhea virus (PEDV) has led to significant economic loss in the global swine industry. Many studies have described how coronaviruses ...

    Authors: Xiaona Wei, Gaoli She, Tingting Wu, Chunyi Xue and Yongchang Cao
    Citation: Veterinary Research 2020 51:10
    Content type: Research article Published on:

  26. Genetic variation is associated with differences in disease resistance and susceptibility among individuals within a population. To date, molecular genetic analyses of host responses have relied on extraction ...

    Authors: Eve Hanks, Helen Todd, Javier Palarea-Albaladejo, Tom N. McNeilly, Collette Britton and Keith T. Ballingall
    Citation: Veterinary Research 2020 51:9
    Content type: Research article Published on:

  27. MicroRNAs (miRNAs) are small non-coding RNAs that contribute to host immune response as post-transcriptional regulation. The current study investigated the biological role of the chicken (Gallus gallus) microRNA-...

    Authors: Thu Thao Pham, Jihye Ban, Yeojin Hong, Jiae Lee, Thi Hao Vu, Anh Duc Truong, Hyun S. Lillehoj and Yeong Ho Hong
    Citation: Veterinary Research 2020 51:8
    Content type: Research article Published on:

  28. Glaesserella (formerly Haemophilus) parasuis causes Glässer’s disease, which results in high economic loss in the swine industry. To understand the polymicrobial interactions of G. parasuis and the nasal microbio...

    Authors: Yasser S. Mahmmod, Florencia Correa-Fiz and Virginia Aragon
    Citation: Veterinary Research 2020 51:7
    Content type: Research article Published on:

  29. The present study employs the Brucella abortus L7/L12 antigen in a Salmonella secretion platform and investigates its ability to induce protective immune responses against wild type challenge in BALB/c mice. The ...

    Authors: Amal Senevirathne, Chamith Hewawaduge and John Hwa Lee
    Citation: Veterinary Research 2020 51:6
    Content type: Research article Published on:

  30. Avian pathogenic Escherichia coli (APEC), a pathotype of extraintestinal pathogenic E. coli, causes one of the most serious infectious diseases of poultry and shares some common virulence genes with neonatal meni...

    Authors: Zhonghua Zhang, Shan Jiang, Yun Liu, Yu Sun, Peixin Yu, Qianwen Gong, Hang Zeng, Yihao Li, Feng Xue, Xiangkai Zhuge, Jianluan Ren, Jianjun Dai and Fang Tang
    Citation: Veterinary Research 2020 51:5
    Content type: Research article Published on:

  31. Cattle maintaining a low proviral load (LPL) status after bovine leukaemia virus (BLV) infection have been recognized as BLV controllers and non-transmitters to uninfected cattle in experimental and natural co...

    Authors: Agustina Forletti, Claudia María Lützelschwab, Rosana Cepeda, Eduardo N. Esteban and Silvina Elena Gutiérrez
    Citation: Veterinary Research 2020 51:4
    Content type: Research article Published on:

  32. Salmonellosis is the second most common food-borne zoonosis in the European Union, with pigs being a major reservoir of this pathogen. Salmonella control in pig production requires multiple measures amongst which...

    Authors: Carmen Gil, Cristina Latasa, Enrique García-Ona, Isidro Lázaro, Javier Labairu, Maite Echeverz, Saioa Burgui, Begoña García, Iñigo Lasa and Cristina Solano
    Citation: Veterinary Research 2020 51:3
    Content type: Research article Published on:

  33. The avian respiratory tract is a common entry route for many pathogens and an important delivery route for vaccination in the poultry industry. Immune responses in the avian lung have mostly been studied in vi...

    Authors: Karen Jane Bryson, Damien Garrido, Marco Esposito, Gerry McLachlan, Paul Digard, Catherine Schouler, Rodrigo Guabiraba, Sascha Trapp and Lonneke Vervelde
    Citation: Veterinary Research 2020 51:2
    Content type: Research article Published on:

  34. Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrPC) is converted into a ...

    Authors: Øyvind Salvesen, Arild Espenes, Malin R. Reiten, Tram T. Vuong, Giulia Malachin, Linh Tran, Olivier Andréoletti, Ingrid Olsaker, Sylvie L. Benestad, Michael A. Tranulis and Cecilie Ersdal
    Citation: Veterinary Research 2020 51:1
    Content type: Research article Published on:

  36. Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which contr...

    Authors: Tingting Cui, Sebastiaan Theuns, Jiexiong Xie and Hans J. Nauwynck
    Citation: Veterinary Research 2019 50:110
    Content type: Research article Published on:

  37. The function of Autoinducer-2 (AI-2) which acts as the signal molecule of LuxS-mediated quorum sensing, is regulated through the lsr operon (which includes eight genes: lsrK, lsrR, lsrA, lsrC, lsrD, lsrB, lsrF, a...

    Authors: Jiakun Zuo, Huifang Yin, Jiangang Hu, Jinfeng Miao, Zhaoguo Chen, Kezong Qi, Zhihao Wang, Jiansen Gong, Vanhnaseng Phouthapane, Wei Jiang, Rongsheng Mi, Yan huang, Chen Wang and Xiangan Han
    Citation: Veterinary Research 2019 50:109
    Content type: Research article Published on:

  38. Schistosomiasis is a globally important helminthic disease of humans and animals, and it is the second most common parasitic disease after malaria. Eggs produced by mature females are responsible for the disea...

    Authors: Guifeng Cheng, Xiaochun Li, Fanglin Qin, Rong Xu, Yuanyuan Zhang, Jinming Liu, Shaopeng Gu and Yamei Jin
    Citation: Veterinary Research 2019 50:108
    Content type: Research article Published on:

  39. The protozoan parasite Histomonas meleagridis is the causative agent of the re-emerging disease histomonosis of chickens and turkeys. Due to the parasite’s extracellular occurrence, a type-2 differentiation of H....

    Authors: Julia Lagler, Taniya Mitra, Selma Schmidt, Alix Pierron, Eleni Vatzia, Maria Stadler, Sabine E. Hammer, Kerstin H. Mair, Beatrice Grafl, Patricia Wernsdorf, Fabienne Rauw, Bénédicte Lambrecht, Dieter Liebhart and Wilhelm Gerner
    Citation: Veterinary Research 2019 50:107
    Content type: Research article Published on:

  40. The binding and activation of host plasminogen (PLG) by worm surface enolases has been verified to participate in parasite invasion, but the role of this processes during Trichinella spiralis infection has not be...

    Authors: Peng Jiang, You Jiao Zao, Shu Wei Yan, Yan Yan Song, Dong Min Yang, Li Yuan Dai, Ruo Dan Liu, Xi Zhang, Zhong Quan Wang and Jing Cui
    Citation: Veterinary Research 2019 50:106
    Content type: Research article Published on:

  41. Outer membrane protein P2 (OmpP2) of the virulent Haemophilus (Glaesserella) parasuis has been shown to induce the release of proinflammatory cytokines. The OmpP2 protein is composed of eight or nine surface-expo...

    Authors: Ye Zhou, Saixiang Feng, Xinyi He, Qun Zhou, Yuanwei Wang, Hua Yue, Cheng Tang and Bin Zhang
    Citation: Veterinary Research 2019 50:105
    Content type: Research article Published on:

  42. Understanding the immunological basis of resistance to gastrointestinal nematode infections in livestock is important in order to develop novel methods of parasite control such as vaccination or genetic select...

    Authors: Ana Cláudia A. Albuquerque, Cesar Cristiano Bassetto, Fabiana A. Almeida, Katie A. Hildersley, Tom N. McNeilly, Collette Britton and Alessandro F. T. Amarante
    Citation: Veterinary Research 2019 50:104
    Content type: Research article Published on:

  43. Many research groups have developed mathematical models to simulate the dynamics of BVDV infections in cattle herds. However, most models use estimates for within-herd BVDV transmission rates that are either b...

    Authors: Jun-Hee Han, Jenny F. Weston, Cord Heuer and M. Carolyn Gates
    Citation: Veterinary Research 2019 50:103
    Content type: Research article Published on:

  44. Bovine leukemia virus (BLV) infects cattle and causes serious problems for the cattle industry, worldwide. Vertical transmission of BLV occurs via in utero infection and ingestion of infected milk and colostru...

    Authors: Sonoko Watanuki, Shin-nosuke Takeshima, Liushiqi Borjigin, Hirotaka Sato, Lanlan Bai, Hironobu Murakami, Reiichiro Sato, Hiroshi Ishizaki, Yasunobu Matsumoto and Yoko Aida
    Citation: Veterinary Research 2019 50:102
    Content type: Research article Published on:

  45. Vitamin A (VA) has pleiotropic effects on the immune system and is critical for mucosal immune function and intestinal lymphocyte trafficking. We hypothesized that oral VA supplementation of porcine epidemic d...

    Authors: Stephanie N. Langel, Francine Chimelo Paim, Moyasar A. Alhamo, Kelly M. Lager, Anastasia N. Vlasova and Linda J. Saif
    Citation: Veterinary Research 2019 50:101
    Content type: Research article Published on:

  46. Epidemiological investigations implemented in wild and domestic ruminants evidenced a reservoir for Brucella in Capra ibex in the French Alps. Vaccination was considered as a possible way to control Brucella infe...

    Authors: Claire Ponsart, Mickaël Riou, Yann Locatelli, Isabelle Jacques, Alain Fadeau, Maryne Jay, Roland Simon, Ludivine Perrot, Luca Freddi, Sylvain Breton, Thierry Chaumeil, Barbara Blanc, Katia Ortiz, Colin Vion, Damien Rioult, Erwan Quéméré…
    Citation: Veterinary Research 2019 50:100
    Content type: Research article Published on:

  47. Salmonella enterica is a veterinary and zoonotic pathogen of global importance. While murine and cell-based models of infection have provided considerable knowledge about the molecular basis of virulence of Salmo...

    Authors: Prerna Vohra, Christina Vrettou, Jayne C. Hope, John Hopkins and Mark P. Stevens
    Citation: Veterinary Research 2019 50:99
    Content type: Research article Published on:

  49. Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrPSc) acts as infectious agent with fatal consequence. Emergence of bovine spongi...

    Authors: Jan P. M. Langeveld, Laura Pirisinu, Jorg G. Jacobs, Maria Mazza, Isabelle Lantier, Stéphanie Simon, Olivier Andréoletti, Cristina Acin, Elena Esposito, Christine Fast, Martin Groschup, Wilfred Goldmann, John Spiropoulos, Theodoros Sklaviadis, Frederic Lantier, Loukia Ekateriniadou…
    Citation: Veterinary Research 2019 50:97
    Content type: Research article Published on:

  50. While searching for novel anti-echinococcosis drugs, we have been focusing on glycolysis which is relied on by Echinococcus for energy production and intermediates for other metabolic processes. The aim of this s...

    Authors: Qi Xin, Miaomiao Yuan, Huanping Li, Xiaoxia Song, Jun Lu and Tao Jing
    Citation: Veterinary Research 2019 50:96
    Content type: Research article Published on:
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