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  1. Streptococcus suis serotype 2 (SS2) frequently colonizes the swine upper respiratory tract and can cause Streptococcal disease in swine with clinical manifestations of pneumonia, meningitis, and septicemia. Previ...

    Authors: Yu Meng, Shaojie Lin, Kai Niu, Zhe Ma, Huixing Lin and Hongjie Fan
    Citation: Veterinary Research 2023 54:7
    Content type: Research article Published on:

  2. The type VI secretion system (T6SS) is a secretion apparatus widely found in pathogenic Gram-negative bacteria and is important for competition among various bacteria and host cell pathogenesis. Hcp is a core ...

    Authors: Zhe Chen, Zhao Qi, Ziqi Li, Zichao Song, Xiaoru Wang, Ying Shao, Jian Tu and Xiangjun Song
    Citation: Veterinary Research 2023 54:6
    Content type: Research article Published on:

  3. Duck hepatitis A virus type 1 (DHAV-1) is an acute, highly lethal infectious agent that infects ducklings and causes up to 95% mortality in ducklings up to 1 week of age, posing a significant economic threat t...

    Authors: Xiaoyan Xia, Anchun Cheng, Mingshu Wang, Xumin Ou, Di Sun, Shaqiu Zhang, Sai Mao, Qiao Yang, Bin Tian, Ying Wu, Juan Huang, Qun Gao, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao…
    Citation: Veterinary Research 2023 54:5
    Content type: Research article Published on:

  5. Fish health personnel have limited tools in combatting viral diseases such as heart and skeletal muscle inflammation (HSMI) in open net-pen farmed Atlantic salmon. In this study, we aimed to predict HSMI by in...

    Authors: Johan Rennemo, Steinar Myrvold, Kjetil Berge, Øyvind Kileng, Børge Pedersen, Dan Sindre Aksberg, Piotr Lisik, Delphine Crappe, Charles McGurk, Espen Rimstad, Øystein Wessel, Erling Olaf Koppang and Håvard Bjørgen
    Citation: Veterinary Research 2023 54:3
    Content type: Research article Published on:

  6. The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of she...

    Authors: María Teresa Ruiz-Campillo, Diana María Barrero-Torres, Nieves Abril, José Pérez, Rafael Zafra, Leandro Buffoni, Álvaro Martínez-Moreno, Francisco Javier Martínez-Moreno and Verónica Molina-Hernández
    Citation: Veterinary Research 2023 54:2
    Content type: Research Article Published on:

  7. Streptococcus suis serotype 2 is an important bacterial pathogen of swine, responsible for substantial economic losses to the swine industry worldwide. The knowledge on the pathogenesis of the infection caused by...

    Authors: Servane Payen, Jesús Aranda Rrodriguez, Mariela Segura and Marcelo Gottschalk
    Citation: Veterinary Research 2023 54:1
    Content type: Research Article Published on:

  8. Listeriolysin O (LLO) is the main virulence protein of Listeria monocytogenes (LM), that helps LM escape lysosomes. We previously found that the cellular immune response elicited by L.ivanovii (LI) is weaker than...

    Authors: Ruidan Li, Qian Liang, Sicheng Tian, Yunwen Zhang, Sijing Liu, Qian Ou, Zhaobin Chen and Chuan Wang
    Citation: Veterinary Research 2022 53:113
    Content type: Research article Published on:

  10. Chronic wasting disease (CWD) is a prion disease of cervids including deer, elk, reindeer, and moose. Human consumption of cervids is common, therefore assessing the risk potential of CWD transmission to human...

    Authors: Brent Race, Chase Baune, Katie Williams, James F. Striebel, Andrew G. Hughson and Bruce Chesebro
    Citation: Veterinary Research 2022 53:111
    Content type: Research Article Published on:

  11. Enterococcus cecorum (EC) is one of the most relevant bacterial pathogens in modern broiler chicken production from an economic and animal welfare perspective. Although EC pathogenesis is generally well described...

    Authors: Jana Schreier, Ivan Rychlik, Daniela Karasova, Magdalena Crhanova, Gerhard Breves, Silke Rautenschlein and Arne Jung
    Citation: Veterinary Research 2022 53:110
    Content type: Research Article Published on:

  12. The bursa of Fabricius, the acknowledged humoral immune organ unique to birds, plays a vital role in B cell development. Bursopentin (BP5) derived from the bursa is reported to induce the development and forma...

    Authors: Ze Zhang, Jiaxi Cai, Shanshan Hao, Chenfei Li, Jiajing Chen, Tongtong Li and Xiuli Feng
    Citation: Veterinary Research 2022 53:109
    Content type: Research Article Published on:

  13. To improve understanding of the pathobiology of highly pathogenic avian influenza virus (HPAIV) infections in wild birds, pathogenicity and transmissibility of HPAIV H5N8 subtype clade 2.3.4.4b was evaluated i...

    Authors: Karolina Tarasiuk, Anna Kycko, Małgorzata Knitter, Edyta Świętoń, Krzysztof Wyrostek, Katarzyna Domańska-Blicharz, Łukasz Bocian, Włodzimierz Meissner and Krzysztof Śmietanka
    Citation: Veterinary Research 2022 53:108
    Content type: Research Article Published on:

  14. Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle. Genomic sequencing can resolve phylogenetic relationships between virus populations, which can be used to infer tran...

    Authors: Paul C. D. Johnson, Sara Hägglund, Katarina Näslund, Gilles Meyer, Geraldine Taylor, Richard J. Orton, Siamak Zohari, Daniel T. Haydon and Jean François Valarcher
    Citation: Veterinary Research 2022 53:107
    Content type: Research Article Published on:

  15. The “Zero by 30” strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030 and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination...

    Authors: Sarah Hayes, Kennedy Lushasi, Maganga Sambo, Joel Changalucha, Elaine A. Ferguson, Lwitiko Sikana, Katie Hampson, Pierre Nouvellet and Christl A. Donnelly
    Citation: Veterinary Research 2022 53:106
    Content type: Research Article Published on:

  16. Erysipelas, caused by infection with Erysipelothrix rhusiopathiae (ER) is an important emerging disease in laying hens. We have earlier observed prominent mannose-binding lectin (MBL) acute phase responses in exp...

    Authors: Eva Wattrang, Tina Sørensen Dalgaard, Rikke Brødsgaard Kjaerup, Mohammad Naghizadeh, Susanne Kabell, Helena Eriksson and Robert Söderlund
    Citation: Veterinary Research 2022 53:105
    Content type: Research article Published on:

  17. The protective arm of the renin-angiotensin system (RAS), the ACE 2/Ang-(1–7)/MasR axis, has become a new anti-inflammatory target. As a specific activator of ACE2, diminazene aceturate (DA) can promote anti-i...

    Authors: Xiangjun Zhang, Fang Jia, Weiwu Ma, Xueqiang Li and Xuezhang Zhou
    Citation: Veterinary Research 2022 53:104
    Content type: Research Article Published on:

  18. A disruption in the expression of gga-miR-365-3p was confirmed in the Mycoplasma gallisepticum (MG)-infected Chicken primary alveolar type II epithelial (CP-II) cells based on previous sequencing results, but the...

    Authors: Yingjie Wang, Yun Han, Lulu Wang, Mengyun Zou, Yingfei Sun, Huanling Sun, Qiao Guo and Xiuli Peng
    Citation: Veterinary Research 2022 53:103
    Content type: Research article Published on:

  19. Considering human decision-making is essential for understanding the mechanisms underlying the propagation of real-life diseases. We present an extension of a model for pathogen spread that considers farmers’ ...

    Authors: Lina Cristancho-Fajardo, Elisabeta Vergu, Gaël Beaunée, Sandie Arnoux and Pauline Ezanno
    Citation: Veterinary Research 2022 53:102
    Content type: Research article Published on:

  20. African swine fever virus (ASFV) is a large DNA virus that infects domestic pigs with high morbidity and mortality rates. Repeat sequences, which are DNA sequence elements that are repeated more than twice in ...

    Authors: Zhaozhong Zhu, Shengqiang Ge, Zena Cai, Yifan Wu, Congyu Lu, Zheng Zhang, Ping Fu, Longfei Mao, Xiaodong Wu and Yousong Peng
    Citation: Veterinary Research 2022 53:101
    Content type: Research article Published on:

  21. This research aimed to analyze the regulatory effect of chicken telomerase reverse transcriptase (chTERT) on the Wnt/β-catenin signaling pathway and its effect on the tumorigenicity of avian leukosis virus sub...

    Authors: Yong Xiang, Canxin Liang, Qingbo Li, Qinxi Chen, Yang Zhou, Xiaoxue Zheng, Di Zhou, Zepeng Wang, Guyao Wang and Weisheng Cao
    Citation: Veterinary Research 2022 53:100
    Content type: Research article Published on:

  23. Dairy cows often develop different degrees of endometritis after calving and this is attributed to pathogenic bacterial infections such as by Escherichia coli and Staphylococcus aureus. Infection of the bovine en...

    Authors: Jindi Wu, Fan Bai, Wei Mao, Bo Liu, Xiaolin Yang, Jing Zhang, Tingting Li, Gerelt Borjigin and Jinshan Cao
    Citation: Veterinary Research 2022 53:98
    Content type: Research article Published on:

  24. Klebsiella pneumoniae is a leading cause of severe infections in humans and animals, and the emergence of multidrug-resistant strains highlights the need to develop effective vaccines for preventing such infecti...

    Authors: Fusheng Zhang, Yan Meng, Li Xu, Yujiao Tian, Huigai Lu, Jichen Xie, Renhui Ma, Moran Li and Bei Li
    Citation: Veterinary Research 2022 53:97
    Content type: Research article Published on:

  25. Colistin is frequently used as a growth factor or treatment against infectious bacterial diseases in animals. The Veterinary Division of the European Medicines Agency (EMA) restricted colistin use as a second-...

    Authors: Afaf Hamame, Bernard Davoust, Bouthaina Hasnaoui, David Lupande Mwenebitu, Jean-Marc Rolain and Seydina M. Diene
    Citation: Veterinary Research 2022 53:96
    Content type: Research article Published on:

  26. Mycoplasma hyopneumoniae, the causative agent of swine respiratory disease, demonstrates differences in virulence. However, factors associated with this variation remain unknown. We herein evaluated the associati...

    Authors: Yuzi Wu, Yanfei Yu, Lizhong Hua, Yanna Wei, Yuan Gan, Hafizah Yousuf Chenia, Yixuan Wang, Xing Xie, Jia Wang, Maojun Liu, Guoqing Shao, Qiyan Xiong and Zhixin Feng
    Citation: Veterinary Research 2022 53:95
    Content type: Research article Published on:

  28. An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release. After inf...

    Authors: Tong Zhou, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Ying Wu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Xuming Ou, Sai Mao, Di Sun, Shaqiu Zhang, Dekang Zhu, Juan Huang…
    Citation: Veterinary Research 2022 53:93
    Content type: Review Published on:

  29. Multi-Locus Sequence Analysis (MLSA) of Mycoplasma capricolum subsp. capripneumoniae (Mccp) strains from Asia revealed unforeseen diversity and a central position for genotyping groups representing strains from C...

    Authors: Arooba Akhtar, Anne Boissière, Huafang Hao, Muhammad Saeed, Virginie Dupuy, Antoni Exbrayat, Farhan Anwar Khan, Yuefeng Chu and Lucía Manso-Silván
    Citation: Veterinary Research 2022 53:92
    Content type: Short report Published on:

  30. Streptococcus suis is a zoonotic agent that causes sepsis and meningitis in pigs and humans. S. suis infections are responsible for large economic losses in pig production. The lack of effective vaccines to preve...

    Authors: Cristina Uruén, Carla García, Lorenzo Fraile, Jan Tommassen and Jesús Arenas
    Citation: Veterinary Research 2022 53:91
    Content type: Review Published on:

  31. Foamy macrophages containing prominent cytoplasmic lipid droplets (LDs) are found in a variety of infectious diseases. However, their role in Streptococcus uberis-induced mastitis is unknown. Herein, we report th...

    Authors: Zhixin Wan, Shaodong Fu, Zhenglei Wang, Yuanyuan Xu, Yuanyuan Zhou, Xinguang Lin, Riguo Lan, Xiangan Han, Zhenhua Luo and Jinfeng Miao
    Citation: Veterinary Research 2022 53:90
    Content type: Research article Published on:

  32. Peste des petits ruminants (PPR) is an acute and highly contagious disease and has long been a significant threat to small ruminant productivity worldwide. However, the molecular mechanism underlying host-PPRV...

    Authors: Bo Wen, Xuefeng Qi, Daiyue Lv, Lulu Yang, Pan Tang, Wenchi Chang, Shuizhong Han, Shengmeng Yu, Shaopeng Wei, Qinghong Xue and Jingyu Wang
    Citation: Veterinary Research 2022 53:89
    Content type: Research article Published on:

  33. As one of the crucial enterotoxins secreted by enterotoxigenic Escherichia coli (ETEC), heat-labile enterotoxin (LT) enhances bacterial adherence both in vivo and in vitro; however, the underlying mechanism remai...

    Authors: Qiangde Duan, Shengmei Pang, Lili Feng, Jiaqi Liu, Linfen Lv, Baoliang Li, Yuxuan Liang and Guoqiang Zhu
    Citation: Veterinary Research 2022 53:88
    Content type: Research article Published on:

  34. Muscle larvae of Trichinella spiralis parasitize the host intestinal epithelium. The mechanisms of exosomes participating in the invasion of T. spiralis muscle larvae are unclear. Hence, the purpose of this study...

    Authors: Ruibiao Wang, Yuheng Zhang, Jingbo Zhen, Jinpeng Zhang, Zixuan Pang, Xuewei Song, Lihao Lin, Feng Sun and Yixin Lu
    Citation: Veterinary Research 2022 53:87
    Content type: Research article Published on:

  35. Understanding of disease dynamics and viral shedding in wild boar and of the potential for disease spreading within wild boar and domestic pig populations is critical for developing effective control and eradi...

    Authors: Katsuhiko Fukai, Rie Kawaguchi, Tatsuya Nishi, Mitsutaka Ikezawa, Manabu Yamada, Kingkarn Boonsuya Seeyo and Kazuki Morioka
    Citation: Veterinary Research 2022 53:86
    Content type: Research article Published on:

  36. The aim of this study was to investigate the characteristics of a novel type C lectin from Trichinella spiralis (TsCTL) and its role in larval invasion of intestinal epithelial cells (IECs). TsCTL has a carbohydr...

    Authors: Hui Nan Hao, Yan Yan Song, Kai Ning Ma, Bo Ning Wang, Shao Rong Long, Ruo Dan Liu, Xi Zhang, Zhong Quan Wang and Jing Cui
    Citation: Veterinary Research 2022 53:85
    Content type: Research article Published on:

  37. Staphylococci and streptococci are common causes of intramammary infection in small ruminants, and reliable species identification is crucial for understanding epidemiology and impact on animal health and welf...

    Authors: Nives Maria Rosa, Martina Penati, Sara Fusar-Poli, Maria Filippa Addis and Sebastiana Tola
    Citation: Veterinary Research 2022 53:84
    Content type: Research article Published on:

  38. Staphylococcus saprophyticus is frequently involved in various difficult-to-treat infections due to the formation of biofilms. To identify useful antibiofilm strategies, this study explored the efficacy and mecha...

    Authors: Jinli Wang, Siya Li, Jinwu Meng, Jinyue Zhu, Tianxin Qiu, Wenjia Wang, Jinxue Ding, Zhenguang Liu, Kun Li, Mujahid lqbal, Deyun Wang, Yi Wu and Jiaguo Liu
    Citation: Veterinary Research 2022 53:83
    Content type: Research article Published on:

  39. Innate immunity plays an essential role in preventing the invasion of pathogenic microorganisms. However, innate immunity is a double-edged sword, whose excessive activation is detrimental to immune homeostasi...

    Authors: Jie Wang, Yuqiang Cheng, Longlong Wang, Aixi Sun, Zhenyu Lin, Wenxian Zhu, Zhaofei Wang, Jingjiao Ma, Henan Wang, Yaxian Yan and Jianhe Sun
    Citation: Veterinary Research 2022 53:82
    Content type: Research article Published on:

  40. Pasteurella multocida (P. multocida) can cause severe respiratory disease in cattle, resulting in high mortality and morbidity. Inflammasomes are multiprotein complexes in the cytoplasm that recognize pathogens a...

    Authors: Xingping Wu, Zheng Zeng, Hongliang Tian, Lianci Peng, Dongyi Xu, Yu Wang, Chao Ye, Yuanyi Peng and Rendong Fang
    Citation: Veterinary Research 2022 53:81
    Content type: Research article Published on:

  41. Pseudomonas aeruginosa (P. aeruginosa) is a known bacterium that produces biofilms and causes severe infection. Furthermore, P. aeruginosa biofilms are extremely difficult to eradicate, leading to the developmen...

    Authors: Yang Zhang, Peng Cheng, Shiyuan Wang, Xiaofen Li, Lianci Peng, Rendong Fang, Jing Xiong, Hui Li, Cui Mei, Jiye Gao, Zhenhui Song, Dengfeng Xu, Lizhi Fu, Chenghong Li, Xueqing Wu, Yuzhang He…
    Citation: Veterinary Research 2022 53:80
    Content type: Research article Published on:

  42. Production of peste des petits ruminants (PPR) vaccines in Russia is based on two attenuated virus strains (“45G37/35-k” and “ARRIAH”) of common origin. Here, the identity of the strain PPRV/45G37/35-k was inv...

    Authors: Olivier Kwiatek, Geneviève Libeau, Samia Guendouz, Chloé Corbanini, Andrey Gogin, Andrey Lunitsin, Irina Sindryakova, Denis Koblasov and Arnaud Bataille
    Citation: Veterinary Research 2022 53:79
    Content type: Short report Published on:

  43. Besides Helicobacter pylori, a Gram-negative bacterium that may cause gastric disorders in humans, non-Helicobacter pylori helicobacters (NHPH) may also colonize the stomach of humans and animals. In pigs, H. sui...

    Authors: Francisco Cortez Nunes, Teresa Letra Mateus, Emily Taillieu, Sílvia Teixeira, Nuno Carolino, Alexandra Rema, Sofie De Bruyckere, Fátima Gärtner, Freddy Haesebrouck and Irina Amorim
    Citation: Veterinary Research 2022 53:78
    Content type: Research article Published on:

  44. Bovine respiratory disease (BRD) dramatically affects young calves, especially in fattening facilities, and is difficult to understand, anticipate and control due to the multiplicity of factors involved in the...

    Authors: Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White and Sébastien Assié
    Citation: Veterinary Research 2022 53:77
    Content type: Research article Published on:

  45. In the present study, two prospective Salmonella delivery strains, JOL2782 and JOL2837, were developed by gene deletions of lon and cpxR, which are related to cellular adhesion and intracellular survival. Additio...

    Authors: Ram Prasad Aganja, Chandran Sivasankar, Chamith Hewawaduge and John Hwa Lee
    Citation: Veterinary Research 2022 53:76
    Content type: Research article Published on:

  46. Fowl adenovirus serotype 4 (FAdV-4) and FAdV-8b are causative agents of hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH), respectively. HHS and IBH co-infections were often reported...

    Authors: Baiyu Wang, Mingzhen Song, Congcong Song, Shiyi Zhao, Panpan Yang, Qilong Qiao, Yanfang Cong, Yanling Wang, Zeng Wang and Jun Zhao
    Citation: Veterinary Research 2022 53:75
    Content type: Research article Published on:

  47. Porcine reproductive and respiratory syndrome virus (PRRSV) in late gestation causes a profound suppression of circulating maternal and fetal thyroid hormone during a critical window of development. To underst...

    Authors: Erin K. Ison, Amber S. Hopf-Jannasch, John C. S. Harding and J. Alex Pasternak
    Citation: Veterinary Research 2022 53:74
    Content type: Research article Published on:

  48. Pseudorabies virus (PRV) variant infections have caused a substantial economic impact on swine production in the absence of new powerful candidate vaccines. In this study, we developed and evaluated a gene-del...

    Authors: Ling Li, Yongfeng Du, Yanbin Zhang, Pengyu Li, Xinyue Liu, Xin Zhang, Jing Li, Tong Zhang, Xin Li, Dong Xiao, Peng Liu, Peng Qi and Jin Xiao
    Citation: Veterinary Research 2022 53:73
    Content type: Research article Published on:

  49. Epithelial cells are known to produce mediators which can influence the behaviour of neighbouring immune cells. Although the oral mucosa has gained increased interest as a route to induce allergy desensitisati...

    Authors: Michael Pelst, Clara Höbart, Hilde de Rooster, Bert Devriendt and Eric Cox
    Citation: Veterinary Research 2022 53:72
    Content type: Research article Published on:

  50. Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic debilitating disease in ruminants. To control this disease, it is crucial to understand immune evasion and th...

    Authors: Hong-Tae Park, Sang-Mok Lee, Seyoung Ko, Suji Kim, Hyun-Eui Park, Min-Kyoung Shin, Donghyuk Kim and Han Sang Yoo
    Citation: Veterinary Research 2022 53:71
    Content type: Research article Published on:
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