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Correction to: Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut

The Original Article was published on 26 June 2021

Correction to: Vet Res (2021) 52:94

Following publication of the original article [1], we have been informed that Figure 2B and C needs to be updated. In the midpanel, the y-axis labeling is partially visible but should not have been visible. The updated figure is given below.

Figure 2
figure 2

Porcine enteroids mimic the response of the small intestine to ETEC-derived enterotoxins. Spheroids derived from duodenum, jejunum and ileum 6 days after passaging were stimulated with enterotoxins or guanylin and imaged using live-cell microscopy. The surface area of the spheroids was measured using ImageJ. A Representative images displaying ileal spheroid swelling induced by guanylin (10 µM) at T0, T50 and T110 upon administration. B, C The average relative area increase of the spheroids was plotted in function of the time after enterotoxin administration. (n = 3 for all tissues). D Spheroid bursting upon guanylin (10 µM) stimulation. Images are representative for other tissues and swelling inducers. Scale bar = 100 µm. Relative IL8 secretion in medium supernatant (E) and Matrigel dome (F) of jejunal enteroids stimulated for 24 h with bacterial supernatant with (WT) or without enterotoxins (toxin negative) compared to non-immunogenic guanylin (n = 3; Kruskal–Wallis test).

The original article has been corrected.


  1. Vermeire B, Gonzalez LM, Jansens RJJ, Cox E, Devriendt B (2021) Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut. Vet Res 52:94.

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Correspondence to Bert Devriendt.

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Vermeire, B., Gonzalez, L.M., Jansens, R.J.J. et al. Correction to: Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut. Vet Res 52, 107 (2021).

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