Gene | Mean cytokine mRNA expression level in the ileum | P-value | ||||||
---|---|---|---|---|---|---|---|---|
CTRL | ATB | PA | SCB | PA + SCB | T | Ch | T×Ch | |
IL-6 (10 -4 ) | ||||||||
24 hpc | 0.9ac [0.3-3.1] | 1.1ac [0.3-3.6] | 3.5d [1.1-11.3] | 0.6 [0.2-1.9] | 3.9b [1.2-12.7] | 0.33 | 0.47 | 0.29 |
Not Ch | 0.8 [0.2-3.2] | 1.7 [0.4-7.4] | 0.9 [0.2-3.8] | 1.2 [0.3-5.0] | 1.2 [0.3-5.0] | |||
TNF-α- (10 -3 ) | ||||||||
24 hpc | 1.28c [0.38-4.32] | 2.94 [0.94-9.19] | 3.87 [1.24-12.09] | 1.65 [0.49-5.56] | 5.28d [1.69-16.48] | 0.24 | 0.59 | 0.85 |
Not Ch | 1.59 [0.46-5.52] | 4.40 [1.10-17.52] | 4.53 [1.31-15.73] | 3.04 [0.88-10.54] | 3.03 [0.87-10.51] | |||
pBD-2 | ||||||||
24 hpc | 0.025c [0.013-0.05] | 0.045 [0.024-0.085] | 0.053d [0.028-0.1] | 0.05 [0.025-0.1] | 0.041 [0.021-0.077] | 0.33 | 0.83 | 0.88 |
Not Ch | 0.027c [0.01-0.068] | 0.040 [0.015-0.11] | 0.034 [0.013-0.088] | 0.065d [0.026-0.17] | 0.043 [0.017-0.11] | |||
IL-12p35 | ||||||||
24 hpc | 0.018c [0.007-0.046] | 0.029 [0.012-0.069] | 0.059d [0.025-0.142] | 0.017 [0.006-0.042] | 0.027 [0.011-0.065] | 0.31 | 0.59 | 0.65 |
Not Ch | 0.011 [0.003-0.038] | 0.033 [0.008-0.13] | 0.022 [0.006-0.074] | 0.025 [0.007-0.085] | 0.025 [0.007-0.091] | |||
IL-8 | ||||||||
24 hpc | 11.59 [1.29-104,14] | 16.86 [2.12-133.91] | 6.46 [0.81-51.3] | 6.41 [0.71-57.63] | 10.08 [1.27-80.04] | 0.48 | 0.003 | 0.68 |
Not Ch | 0.59a [0.08-4.47] | 3.79b [0.44-32.9] | 1.62 [0.21-12.36] | 3.12b [0.41-23.73] | 3.55b [0.44-28.63] | |||
IFN-γ- (10 -4 ) | ||||||||
24 hpc | 0.6 [0.1-2.7] | 0.9 [0.2-3.7] | 0.4 [0.1-1.7] | 0.9 [0.2-3.7] | 1.6 [0.4-6.6] | 0.26 | 0.07 | 0.88 |
Not Ch | 2.9 [0.6-13.5] | 1.8 [0.3-9.2] | 0.7 [0.2-3.5] | 1.2 [0.3-5.7] | 3.0 [0.6-14.1] | |||
IL-10 | ||||||||
24 hpc | 0.2 [0.05-0.77] | 0.29 [0.08-1] | 0.22 [0.06-0.77] | 0.09 [0.02-0.32] | 0.45 [0.13-1.57] | 0.39 | 0.85 | 0.47 |
Not Ch | 0.15 [0.05-0.45] | 0.38 [0.12-1.25] | 0.13 [0.04-0.37] | 0.25 [0.08-0.72] | 0.24 [0.08-0.73] |