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Table 1 Antibiotic resistance genotypes and phenotypes, sequence types (ST), and plasmids of Streptococcus spp. isolates from 1940s analyzed in this study (n = 50)

From: Genome analysis of Streptococcus spp. isolates from animals in pre-antibiotic era with respect to antibiotic susceptibility and virulence gene profiles

Isolates

Isolation year

Sequence Type

Genotype

Phenotype (MIC, μg/mL)b

Plasmid

S. agalactiae

 16

1941

356

-

S

 

 39

1941

61

-

S

 

 090R

1941

25

-

S

 

 B1006

1947

61

-

S

 

 B2142

1941

23

-

S

 

 B2151

1941

23

- 

S

 

 G2

1941

61

- 

S

pA996 and pSSU1

 G19

1947

61

-

S

pA996 and pSSU1

 G42

1948

61

-

S

 

 H36B

1941

6

-

S

 

 N49

1941

2225 a

-

S

 

 S101

1941

23

-

S

 

 S102

1948

64

-

S

 

 S104

1948

23

-

S

 

S. dysgalactiae subsp. dysgalactiae

 21

1941

298

-

S

 

 36

1941

532

- 

Tetracycline R (8)

 

 41

1941

308

- 

Tetracycline R(8)

 

 43

1941

531

- 

Tetracycline I (4)

 

 45

1941

308

- 

Tetracycline I (4)

 

 46

1941

298

- 

S

 

 B2198

1941

531

- 

Tetracycline I (4)

 

 B2200

1941

531

- 

Tetracycline I (4)

 

 B2263

1941

531

- 

S

 

 B2273

1941

531

- 

Tetracycline R (8)

 

S. dysgalactiae subsp. equisimilis

 18

1941

3

- 

S

 

 19

1941

275

- 

S

 

 29

1941

641

- 

S

 

 30

1941

84

- 

S

 

 34

1941

723 a

- 

Tetracycline R (8)

 

S. uberis

 17

1941

472

- 

S

 

 B2160

1947

1802 a

- 

S

pA996

 B2254

1941

1815 a

- 

S

 

 B2258

1941

1815 a

- 

S

 

 B2165

1941

1801 a

- 

S

 

 B2139

1941

1817 a

- 

S

 

 B2141

1941

1818 a

- 

S

 

 U84

1947

1804 a

- 

S

 

S. pyogenes

 5

1941

38

- 

S

 

 6

1941

28

- 

S

 

 7

1941

1278

-

S

 

 9

1941

28

- 

S

 

 12

1941

26

- 

S

 

 14

1941

28

- 

S

 

 15

1941

120

 -

S

 

S. equi subsp. zooepidemicus

 24

1941

529 a

- 

Tetracycline I (4)

 

 37

1941

182

- 

Tetracycline I (4), Clindamycin I (0.5)

 

 38

1941

530 a

- 

Clindamycin I (0.5)

 

 40

1941

27

- 

Tetracycline R (8), Clindamycin I (0.5)

 

S. oralis

 11

1941

–

- 

S

 

S. pseudoporcinus

28

1941

–

- 

S

 
  1. aNovel ST
  2. bS-sensitive; I-intermediate; R-resistant