Table 1 Antiviral and toxicity activities of compounds on WNV-infected eNPCs
Compounds | Type | Viral replication | Cytotoxicity (10 µM) |
|---|---|---|---|
2′-C-methylcytidine | DAA-NA | AV | |
25-Hydroxycholesterol | HDA | Tx | |
Abacavir | DAA-RTI | NoA | |
Adefovir dipivoxil | DAA-HVI | Tx | |
Amantadine | HDA | NoA | |
Arbidol | HDA | AV | |
Atorvastatin | HDA | PV | |
Brequinar | HDA | Tx | |
Capecitabine | N/A | NoA | |
Cidofovir | DAA-HVI | Tx | |
Cladribine | N/A | Tx | |
Clofarabine | N/A | Tx | |
Cytarabine | N/A | Tx | |
Decitabine | DAA-NA | Tx | |
Didanosine | DAA-RTI | NoA | |
DMXAA | HDA | NoA | |
Eflornithin (dfmo) | HDA | NoA | |
Emtricitabine | DAA-RTI | NoA | |
F83233 | HDA | Tx | |
F83233RS | HDA | Tx | |
Famciclovir | DAA-HVI | NoA | |
Favipiravir | DAA-NA | NoA | |
Fludarabine | DAA-NA | Tx | |
Fluorouracile | DAA-NA | Tx | |
Gemcitabine | DAA-NA | Tx | |
Isatin | HDA | NoA | |
Lamivudine | DAA-RTI | NoA | |
Maribavir | DAA | NoA | |
Mercaptopurine | DAA-NA | Tx | |
Mycophenolic acid | HDA | Tx | |
Nelarabine | N/A | NoA | |
Penciclovir | DAA-HVI | NoA | |
Proguanil | HDA | NoA | |
Ribavirin | DAA-NA, HDA | AV | |
Sofosbuvir | DAA-NA | NoA | |
Stavudine | DAA-RTI | NoA | |
Telbivudine | DAA-RTI | NoA | |
Tenofovir disoproxil | DAA-RTI | NoA | |
Thioguanine | DAA-NA | Tx | |
Valaciclovir | DAA-HVI | NoA | |
Valganciclovir | DAA-HVI | NoA |