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Figure 4 | Veterinary Research

Figure 4

From: An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus

Figure 4

Anti- and pro-viral effects of 2′CMC, arbidol, ribavirin, and atorvastatin in WNV-infected eNPCs. Supernatants of WNV-infected eNPCs, non-treated or treated with compounds at 10 µM, were collected 48 hpi and analyzed for AD viral RNA expression (RT-qPCR) and DF virus titer (TCID50/mL). Results are pooled from 2 independent experiments performed in triplicate. They are expressed as the mean ± SD. Comparison between WNV-infected treated and non-treated eNPCs was performed with a two-tailed unpaired Mann Whitney test with p-values significant when *p < 0.05, **p < 0.01.

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