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Figure 2 | Veterinary Research

Figure 2

From: Variation in the affinity of three representative avian adenoviruses for the cellular coxsackievirus and adenovirus receptor

Figure 2

Structure of the FAdV-4 fiber1 knob and comparison with other adenovirus fibre knob proteins. A The crystal structure of the trimeric FAdV-4 fiber1 knob and B the monomeric FAdV-4 fiber1 knob are shown. C The FAdV-4 fiber1 knob was compared with the CELO fiber1 knob (PDB code 2IUN). The backbone of the FAdV-4 fiber1 knob is coloured magenta (B), while the backbone of the CELO fiber1 knob is coloured green. D The FAdV-4 fiber1 knob was compared with the EDSV fibre knob (PDB code 6ITX). The backbone of the FAdV-4 fiber1 knob is coloured magenta (B), while the EDSV fibre knob is coloured cyan. E The AA′ loop structures of the three FAdVs and the AB loops of the four CAR-binding HAdVs were compared. The AB loops of HAdV-2 (PDB code 1QHV), 5 (PDB code 1KNB), 12 (PDB code 1KAC) and HAdV37 (PDB code 1J12) are all coloured light grey. The AA′ loops of FAdV4 fiber1, CELO fiber1 and EDSV fibre are coloured magenta, yellow and green, respectively.

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Veterinary Research

ISSN: 1297-9716