Figure 5

Organization of VGs in S. suis genomes. The genes epf, sly, mrp, hylA, ofs and sbp2 (yellow arrows) in the genome P1/7 and the isolates Ss_20, Ss_51 and Ss_115 are shown. The flanking genes are blue-coloured. Genes coding for putative membrane proteins and hypothetical proteins are shown in orange and dark olive-coloured, respectively. Regions sharing more than 80% of sequence similarity are indicated with grey shadows. The regions in which recombination breakpoints were estimated are shown with green arrows (above). MRFTR: MurR/RpiR family transcriptional regulator; PTSTS-EIIC: PTS transporter subunit EIIC; NA6P2E: N-acetylmannosamine-6-phosphate 2-epimerase; sly: Suilysin (hemolysin); HADFH: HAD famlily hydrolase; ABCT-ATPBP: ABC transporter ATP-binding membrane protein; CDFP: Carboxymuconolactone decarboxylase family protein; epf: Putative surface-anchored protein; YeiH-FP: YeiH family protein; GTP-BP: GTP-binding protein; mrp: Muramidase-released protein precursor; addB: Putative ATP-dependent exonuclease; obgE: GTPase ObgE; MucBP: MucBP domain-containing protein; YSIRK: YSIRK-type signal peptide-containing protein; RDRA: Ribonucleoside-diphosphate reductase alpha; RD: Ribonucleoside-diphosphate; LacI: LacI family regulatory protein; H-II/III: Heparinase II/III-like protein; hylA: Hyaluronidase precursor; agaD: putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component; agaW: putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component; agaV: putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IID component; ugl: Putative unsaturated glucuronyl; PTS-IIA: Putative N-acetylgalactosamine-specific phosphotransferase system (PTS), IIA component; kgdA: putative KHG/KDPG aldolase; PfkB: PfkB family carbohydrate kinase; SPI: Putative sugar-phosphate isomerase; idnO: Putative gluconate 5-dehydrogenase; TPS: Transposase; CAAX: CAAX amino terminal protease family membrane protein; NZnM: Putative neutral zinc metallopeptidase; ICMT: Isoprenylcysteine carboxyl methyltransferase family protein; SHK: Sensor histidine kinase; RRP: Response regulator protein; ofs: Serum opacity factor; SAP: Putative surface-anchored protein; ppaC: Manganese-dependent inorganic; dtd: D-tyrosyl-tRNA(Tyr) deacylasE; relA: GTP pyrophosphokinase; SA-CN-P: Putative surface-anchored 2',3'-cyclic-nucleotide 2'-phosphodiesterase; srtD: Sortase SrtD; srtC: Sortase SrtC; srtB: Sortase SrtB; APSP: Putative accessory pilus subunit protein; sbp2: Major pilus subunit protein; RPM: 50S Ribosomal protein L11 methyltransferase; RNA-BP: Putative RNA-binding protein; (p)ppGpp: (p)ppGpp syynthetase/guanosine-3’,5’-bis(diphosphate 3’-pyrophophohydrolase; DUF554: DUF554 domain containing protein; 16S-rRNA: 16S rRNA (uracil(1498)-N(3))-methyltransferase; DUF3013: DUF3013 family protein.