Vidofludimus inhibits porcine reproductive and respiratory syndrome virus infection by targeting dihydroorotate dehydrogenase

Table 3 Proteins targeted by vidofludimus (only the top 10 proteins are listed).

Target	Common name	Uniprot ID	ChEMBL ID	Target class	Probability*
Dihydroorotate dehydrogenase	DHODH	Q02127	CHEMBL1966	Oxidoreductase	1.000
Epidermal growth factor receptor erbB1	EGFR	P00533	CHEMBL203	Kinase	0.109
Fibroblast growth factor receptor 1	FGFR1	P11362	CHEMBL3650	Kinase	0.109
Peroxisome proliferator-activated receptor gamma	PPARG	P37231	CHEMBL235	Nuclear receptor	0.109
Aldose reductase (by homology)	AKR1B1	P15121	CHEMBL1900	Enzyme	0.109
Liver glycogen phosphorylase	PYGL	P06737	CHEMBL2568	Enzyme	0.109
Muscle glycogen phosphorylase	PYGM	P11217	CHEMBL3526	Enzyme	0.109
Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	CHEMBL239	Nuclear receptor	0.109
Matrix metalloproteinase 12	MMP12	P39900	CHEMBL4393	Protease	0.109
ADAMTS5	ADAMTS5	Q9UNA0	CHEMBL2285	Protease	0.109

ISSN: 1297-9716