Figure 4
From: Molecular characteristics and pathogenicity of a novel chicken astrovirus variant
Histopathologic observations of proventriculus, pancreas, kidney, and liver (H&E staining). In the intraperitoneal infection group, proventriculus tissue exhibited necrosis of proventriculus tubules accompanied by lymphocytic infiltration (400 ×). Increased density of lymphocytic infiltration in pancreatic tissue (400 ×), while liver tissue displayed lymphocytic infiltration around the central hepatic venous vessels. Kidney tissue presented with necrosis of renal tubular epithelial cells and necrotic foci (200 ×). In the oral infection group, proventriculus tubules exhibited lymphocytic infiltration and proventricular dilatation (400 ×). Pancreatic tissue showed lymphocytic infiltration accompanied by pancreatic hemorrhage (400 ×). Liver tissue displayed lymphocytic infiltration around the central hepatic venous vessels. Kidney tissue exhibited swelling of renal tubular epithelial cells that compressed the lumen of the renal tubules (200 ×). Normal tissue (proventriculus, pancreas, liver, and kidney) in the control group (200 ×).