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Figure 2 | Veterinary Research

Figure 2

From: The natural compound Sanggenon C inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway

Figure 2

SC significantly inhibits PRRSV replication. A Chemical structure of Sanggenon C. B After 48 h of SC treatment, the toxicity of SC to Marc-145 cells was detected by CCK-8 assay. PBS was used as a negative control, and the cell viability in this group was set at 100%. C–E Marc-145 cells were seeded in 12-well plates, cultured for 12 h, infected with PRRSV SD-YL1712 (MOI = 1), and then treated with different concentrations of SC. Supernatants and cells were collected at 36 and 48 hpi to detect PRRSV ORF7 expression levels, virus titres and PRRSV N expression levels. *P < 0.05; **P < 0.01; ***P < 0.001 compared to the respective virus control.

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Veterinary Research

ISSN: 1297-9716