Table 1 Cellular factors/proteins involved in CSFV entry

CD46

- Acts as a complement regulator

- BVDV receptor

Probably E2

[33, 60]

ADAM17

- Intervenes in the processing of transmembrane proteins

E2

[65]

Heparan sulfate

- Prevents degradation of proteins/substances

- Acts as an endocytosis receptor

- Is involved in the attachment of multiple virus

Erns

[31, 33, 68]

Laminin receptor

- Cellular receptor

- Is involved in adeno-associated virus infection

Erns

[35]

Integrin ß3

- Is involved in proliferation and migration of endothelial cells

- Acts as receptor/co-receptor for other viruses

?

[77, 79]

Annexin II

- Participates in membrane trafficking

- Has ion channel activity

- Participates in DNA replication

- Acts as a virus receptor

E2

[81, 83, 84, 86,87,88]

MERKT

- Is involved in the phagocytic clearence of apoptotic cells

- Potentiates virus infection

E2

[89,90,91,92]