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Table 2 Presence of clinical signs associated with BSE within 4 weeks prior to death

From: Experimental transmission of ovine atypical scrapie to cattle

Signs

92/20

54/20

1/21a

2/21

2/20

6/17

6/16b

4/15

1/20

55/20

17/17

8/17

14/15

Atypical scrapie

Control

Atypical scrapie

Control

Nervous/apprehensive in corridor

+

Head shy/restless in crush

+

+

Over-reactive to tactile stimuli

+

Unexpected startle

+

Abnormal tests of over-reactivity

+

Abnormal gait

Difficulty rising

+++

+

?

?

+++

?

?

?

?

Scratch test

?

Tremor

+

Weight loss

+

+

?

?

+

  1. + = present; − = absent; for difficulty rising scores: 0 = −, 1 = +, 2 = ++, 3 = +++, ? = not determined within 4 weeks of death.
  2. aLast exam 39 days prior to death.
  3. bLast exam 45 days prior to death.