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Table 1 Amino acid sequence differences between the parental wild-type and mouse-adapted viruses

From: Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice

Gene

Positions (aa)

Parental virus

Mouse adapted viruses (MA#)

1

2

3

4

5

6

7

8

9

10

11

12

PB2

155

S

           

N

526

K

  

R

         

PB1

418

V

      

I

     
 

695

L

I

I

 

I

        

PA

49

S

         

Y

Y

Y

 

97

T

I

I

I

I

I

I

I

I

I

   
 

178

I

M

 

M

 

M

       
 

347

D

         

G

G

G

 

374

M

T

 

T

 

T

       
 

450

V

    

A

       
 

684

E

        

G

   

NP

183

V

         

I

  

HA

138

A

     

T

      
 

155

T

         

I

  
 

182

I

      

L

     
 

187

T

P

P

P

P

P

       
 

205

A

   

E

 

E

E

E

E

   
 

210

N

           

D

 

218

G

E

E

E

 

E

       
 

221

P

         

A

A

 
 

463

G

           

E

NA

111

I

     

V

V

V

V

   
 

143

N

S

           
 

150

T

    

I

       
 

189

I

   

T

        
 

251

V

         

I

  
 

343

A

T

           
 

433

V

 

A

          

NS1

176

N

   

I

        
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Veterinary Research

ISSN: 1297-9716