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Figure 7 | Veterinary Research

Figure 7

From: Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice

Figure 7

The relative expression levels of cytokines in mouse lung tissue infected with recombinant viruses carrying the PB2 S155N and PA S49Y and D347G mutations. The levels of cytokines in the infected mouse lung tissues are shown as the fold-change higher than the wild-type-infected group on day 3 post-infection. The data presented are the mean ± SD of three independent experiments. P values were calculated by using the Student’s t test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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