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Figure 4 | Veterinary Research

Figure 4

From: MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands

Figure 4

Establishment of exogenous bta-miR-223 mimics (A, B, E, F) and bta-miR-223 inhibitor (C, D, G, H) on immortalized bMECs. Effects of bta-miR-223 mimics (A, B) or bta-miR-223 inhibitor (C, D) on NLRP3 pathway induced by LPS + ATP. Effects of bta-miR-223 mimics (E, F) or bta-miR-223 inhibitor (G, H) on Keap1/Nrf2 pathway induced by LPS. **p < 0.01, differences compared to control group; #p < 0.05 and ##p < 0.01, differences compared to LPS or LPS + ATP-induced samples.

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