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Figure 7 | Veterinary Research

Figure 7

From: Orf virus induces complete autophagy to promote viral replication via inhibition of AKT/mTOR and activation of the ERK1/2/mTOR signalling pathway in OFTu cells

Figure 7

Pharmacological treatments do not affect cell viability. A–G OFTu cells were treated with Rapa (0, 2.5, 5, 10, 20 and 40 μM) (panel A), 3-MA (0, 0.5, 1, 2, 4 and 8 mM) (panel B), Baf A1 (0, 0.5, 1, 2, 4 and 8 nM) (panel C), SC79 (0, 10, 20, 30, 40 and 50 μM) (panel D), U0126 (0, 5, 10, 20, 40 and 80 μM) (panel E), AICAR (0, 0.5, 1, 2, 4 and 8 mM) (panel F) or Compound c (0, 0.5, 1, 2, 4 and 8 mM) (panel G). After treatment for 60 h, cell viability was determined by CCK8 assay. The percentage of viable cells is expressed as the mean ± SD. (*P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001; one-way ANOVA).

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