Figure 13

Facilitation of rTsCTL on larval invasion of IECs. The MLs were first activated into IILs using 5% porcine swine bile for 2 h at 37 °C and then added to the IEC monolayer, and larval invasion was observed under a microscope at 2 h after coculture. A: The invaded larva was mobile and migratory in the monolayer (the white arrow shows the migratory trace). B: Noninvaded larva was coiled on the IEC surface. C and D: rTsCTL accelerated the worm invasion of IECs. E and F: Inhibition of anti-rTsCTL antibodies on the IIL invasion of IECs. The results are expressed as the promotion or inhibition (%) normalized to the PBS control group. Scale bars: 100 μm. * P < 0.05 compared to the BSA and PBS control groups.