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Fig. 7 | Veterinary Research

Fig. 7

From: A porcine reproductive and respiratory syndrome virus (PRRSV)-specific IgM as a novel adjuvant for an inactivated PRRSV vaccine improves protection efficiency and enhances cell-mediated immunity against heterologous PRRSV challenge

Fig. 7

Evaluation of PRRSV-neutralizing antibodies against the HP-PRRSV-JXA1 strain. A. Serum samples from piglets of different groups were collected at the indicated dpi after HP-PRRSV challenge. Sera were further tested by neutralization assays using twofold serial dilutions to evaluate virus-neutralizing activity against HP-PRRSV infection in MARC-145 cells. Data are expressed as the mean ± SD. The maximum fold dilution of the serum neutralization titre from individual piglets determined in MARC-145 cells was used to generate a heatmap for visualization of neutralization titre kinetics for each piglet throughout the whole experiment. B. Serum samples from piglets of different groups were collected at the indicated dpi after HP-PRRSV challenge. Sera were further tested by neutralization assays using twofold serial dilutions to evaluate virus-neutralizing activity against HP-PRRSV infection in CRL-2843CD163/CD169 cells. Data are expressed as the mean ± SD. The maximum fold dilution of the serum neutralization titre from individual piglets determined in CRL-2843CD163/CD169 cells was used to generate a heatmap for visualization of neutralization titre kinetics for each piglet. Deceased piglets are marked by “*”.

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Veterinary Research

ISSN: 1297-9716