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Figure 6 | Veterinary Research

Figure 6

From: Evaluation of immunogenicity and cross-reactive responses of  vaccines prepared from two chimeric serotype O foot-and-mouth disease viruses in pigs and cattle

Figure 6

Comparisons of the virus neutralization antibody titres against homologous and heterologous viruses in immunized pigs and cattle. Groups of six pigs or six cattle were vaccinated with either the mutant virus (rHN/TURVP1 or rHN/NXVP1) or the wt virus vaccines on Days 0 and 28; blood samples were assayed by the virus neutralization test on Days 28 and 56 post-vaccination. The results were obtained from three replicates of six animals. Error bars indicate SDs from the mean. Statistical analysis was conducted using an unpaired t test (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns: not significant). A Mean virus-neutralizing antibody titre (VNT (log10)) of six pigs vaccinated with three experimental vaccines at 28 dpv. B Mean VNT of six cows vaccinated with three experimental vaccines at 28 dpv. C Mean VNT of six pigs vaccinated with three experimental vaccines at 56 dpv. D Mean VNT of six cows vaccinated with three experimental vaccines at 56 dpv. The dotted line indicates the 1.65 log10 VNT cut-off level.

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Veterinary Research

ISSN: 1297-9716