Figure 5
Neuraminidase inhibition (NI) titer scores against vaccine strains and antigenically distinct influenza A virus strains. Titers were determined 4 weeks after the second and third vaccination (PV 2 and 3). The colors of the test viruses are based on the NA lineage. Blue, N1pandemic; orange, H1N2 A/swine/Scotland/410440/94-like N2; green, N1avian; dark red, H3N2 A/swine/Gent/1/84-like N2; yellow, N2it; magenta, N2.2002. The NA virus lineage is mentioned between brackets. Antibody titers were given a score from 0 to 4.5; the scoring system is explained below the Figure. The scores are means of the scores of the individual pigs of each group; they are converted to a heatmap. The % cross-reactivity indicates the percentage of virus strains against which a NI titer score ≥ 2.0 was achieved. See Figure 1 for full names of IAVs and the vaccine names.