Kaplan-Maier mean clinical scores. Piglets were vaccinated with the equivalent to 109 CFU/mL of S. suis strain P1/7 bacterin formulated either with Alhydrogel® (A), Emulsigen®-D (B), or Quil-A® (C). All piglets were challenged intraperitoneally with 5 × 109 CFU of S. suis strain P1/7. Each vaccine formulation group of vaccinated piglets (n = 10) had a corresponding placebo group of piglets (n = 10) challenged at the same time. Clinical signs of locomotion/lameness, central nervous system (CNS), and behavior change were recorded three times per day, for nine days of the experiment, according to the scoring system explained in the materials and methods section.