Figure 5
From: Ultra- and micro-structural changes of respiratory tracts in SARS-CoV-2 infected Syrian hamsters
Ultrastructural features of the trachea epithelium following infection (n = 3 per group). A The ciliated pseudostratified columnar epithelium showed ultrastructural changes from 2 dpi. Gradual changes of secretory vacuoles (black arrow), cytoplasmic organelles (white arrow), and cilia (black arrowhead) were prominent following infection. H-7650. TEM. 100 kV. Scale bars, 2 μm. B The density and morphology of cytoplasmic organelles were changed from 2 dpi. The outer membrane and the cristae membrane of mitochondria (black arrow) showed morphological changes. At 2 and 4 dpi, various sizes of electron-lucent spaces were observed. Note that virion-containing vesicles were observed in the cytoplasm at 2 dpi (black arrowhead). H-7650. TEM. 100 kV. Scale bars, 0.2 μm.