Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro

Table 1 X-ray data collection and model refinement statistics

Crystal	moCD163 SRCR5	hCD163L1 SRCR8
PDB code	6K0L	6K0O
X-ray source wavelength (Å)	0.979	0.979
Resolution limits (Å)	1.58	2.0
Space group	P1	C2
Temperature of experiments (K)	100	100
Cell parameters (Å)	a = 28.6, b = 33.5, c = 46.7	a = 29.5, b = 73.0, c = 82.7
Cell parameters (Å)	α = 71.0°, β = 75.3°, γ = 84.9°	α = 90.0°, β = 90.0°, γ = 90.0°
Completeness (%)	95.1 (94.4)^a	98.9 (96.7)^a
Redundancy	3.4 (3.6)^a	5.3 (3.5)^a
Rmerge^b	0.040 (0.096)^a	0.152 (0.378)^a
I/σ (I)	24.6 (13.6)^a	13.4 (4.0)^a
Number of unique reflections	20 604	11 711
CC_1/2	0.992	0.985
Refinement data
R factor	0.158	0.195
R free	0.193	0.269
r.m.s deviation of bond lengths (Å²)	0.007	0.012
r.m.s deviation of angle (°)	1.17	1.64
Ramachandran analysis (%)	98.1^c, 3.4^d, 0.5^e	95.6^c, 2.9^d, 1.5^e

^aNumbers in parentheses refer to the highest resolution shells.
^bRmerge = Σ|Ii- < I >|/ΣIi, where Ii is the intensity of the h observation and < I > is the mean intensity of the reflections.
^cPercentage of residues in most favored regions.
^dPercentage of residues in additional allowed regions.
^ePercentage of residues in generously allowed regions.

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