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Table 1 Applications of flavivirus capsid proteins

From: Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics

Proteins

Viruses

Virus strains

Application types

References

EDIII and C

DENV

Hawaii (DENV-1)

New Guinea C (DENV-2)

H-87 (DENV-3)

H241 (DENV-4)

DENV-2 A15

DENV-2 SB8553/S16803

Subunit vaccine

[123, 124]

DENV-1 Jamaica (AF42564)

DENV-2 SB8553

DENV-3 (FJ882576)

DENV-4 (AF326573)

Vaccine

[125]

DENV-2 A-15 strain

DENV-2 SB8553

DENV-2 Jamaica

Vaccine

[126]

C

Hawaii (DENV-1)

New Guinea C (DENV-2)

H-87 (DENV-3)

H241 (DENV-4)

DENV-2 SB8553

Vaccine

[127]

Four serotypes

Antiviral agent

[128]

C

JEV

Wild-type and 9798A mutant of JEV AT31

Antiviral agent

[92]

Wild-type and L17A/CSmt JEVs

Pathogenesis of JEV infection

[117]

C

WNV

WNV NY99

Live vaccine candidates

[110]

C

TMUV

DTMUV WR strain

DNA vaccine

[129]

CQW1 strain

Target therapeutic

[130]

C-prM-E

ZIKV

PRVABC59

Virus-like particle vaccines

[131]

C

FSS13025 strain

Live-attenuated vaccine

[132]

VSV-C

 

PRVABC59 strain

Vesicular stomatitis virus (VSV)-based vaccine

[102]