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Table 3 Levels of serum immunoglobulins against a subset of recombinant vaccine proteins in Canaria Sheep (CS) and Canaria Hair Breed (CHB) sheep vaccinated with a prototype recombinant sub-unit Teladorsagia circumcincta vaccine and subsequently challenged with T. circumcincta

From: Cellular and humoral immune responses associated with protection in sheep vaccinated against Teladorsagia circumcincta

Isotype Antigen Group Mean ± SEM Cumulative FEC Worm burden Worm length EIU
Correlation
 IgA Tci-MEP-1 CS Vac 1.656 ± 0.058** −0.364 −0.650* −0.497 −0.706*
CS Con 1.188 ± 0.045** 0.473 0.727* 0.309 0.109
CHB Vac 1.652 ± 0.071** −0.073 −0.582 −0.321 −0.358
CHB Con 1.246 ± 0.085** 0.109 0.399 0.385 −0.021
 IgG1 Tci- ASP-1 CS Vac 1.877 ± 0.043** −0.399 −0.196 −0.392 −0.636*
CS Con 0.991 ± 0.004** −0.405 0.223 −0.087 0.219
CHB Vac 1.683 ± 0.067* 0.155 −0.036 −0.285 −0.358
CHB Con 1.017 ± 0.013* 0.494 0.126 0.308 0.406
Tci- SAA-1 CS Vac 2.104 ± 0.086** −0.552 −0.252 −0.699* −0.608*
CS Con 0.995 ± 0.002** 0.018 −0.027 −0.391 −0.600
CHB Vac 1.478 ± 0.089* −0.191 −0.118 −0.152 −0.612
CHB Con 0.999 ± 0.001* 0.182 0.280 −0.119 −0.098
 IgG2 Tci- ASP-1 CS Vac 2.004 ± 0.049** −0.399 −0.329 −0.392 −0.587*
CS Con 0.998 ± 0.003** −0.100 −0.073 −0.182 0.509
CHB Vac 1.701 ± 0.059* 0.164 −0.118 −0.067 −0.164
CHB Con 1.004 ± 0.001* 0.067 0.112 0.028 −0.021
  1. Antibody levels are expressed as (ODI + 1). Only the antigens for which correlations with parasitology variables were established are shown in the table. Associations are expressed as Spearman’s correlation coefficient. Statistically-significant differences within breeds for a specific isotype and antigen and significant correlations are represented with “*” at p < 0.05 and “**” at p < 0.01.