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Figure 5 | Veterinary Research

Figure 5

From: Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolate

Figure 5

Lung gross lesion, histopathological and immunohistochemical examinations. Lung consolidation was observed in positive control and TJM-F92 vaccinated pigs (B, C) but not in mock-infected and rJS-ORF2-6-CON inoculated pigs (A, D). Interstitial pneumonia with infiltration of mononuclear cells could be observed in positive control and TJM-F92 vaccinated pigs (F, G) but not in mock-infected and rJS-ORF2-6-CON inoculated pigs (E, H). PRRSV-specific antigen could be observed in all PRRSV-infected pigs (marked by the black arrows) (J, K, L) but not in mock-infected pigs (I).

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