Table 2 Antibody generation platforms and their feature.
From: Generation and evaluation of IgY-scFv based mimetics against canine parvovirus
| Antibody type | Stability | Specificity | Homogeneity | Reproducibility | Representative technology |
|---|---|---|---|---|---|
| Polyclonal antibody | +++ | + | + | + | Mammal antiserum, avian IgY technology |
| Monoclonal antibody | ++ | +++ | ++ | ++ | Hybridoma technique |
| Recombinant antibody (fragment) | + | +++ | +++ | +++ | Phage display |
| Antibody mimetics | +++ | ++ | +++ | +++ | Protein direct evolution, CDR-FR fusion |