Figure 10

Bacterial invasion of epithelial cells pathway (KEGG ID: hsa05100) in the CoNS vs. H comparison. One of the most significantly regulated pathways by the differentially expressed miRNAs in the CoNS vs. H comparison. The green frame denotes pathway-engaged genes. The target genes identified by the differential expression of miRNAs are marked yellow (included in one pathway) or orange (included in more than one pathway). Black arrows denote molecular interactions or relations; dotted arrows represent indirect links or unknown reaction. CDH1—E-Cadherin (Epithelial), CTNNB₁—Catenin Beta 1, CTNNA₁—Catenin Alpha 1, ARHGAP—GEM Interacting Protein, MET—MET Proto-Oncogene, Gab1—GRB2 Associated Binding Protein 1, CRK—CRK Proto-Oncogene, PIK3R1—Phosphoinositide-3-Kinase Regulatory Subunit 1, DOCK180—Dedicator Of Cytokinesis 180, CDC42—Cell Division Cycle 42, WASL—WASP Like Actin Nucleation Promoting Factor, RAC1—Rac Family Small GTPase 1, WASF2—WASP Family Member 2, ARPC4—Actin Related Protein 2/3 Complex Subunit 4, ACTG1—Actin Gamma 1, SEPT6—Septin 6, CBL—Cbl Proto-Oncogene, SHC1—SHC Adaptor Protein 1, CD2AP—CD2 Associated Protein, DNM2—Dynamin 2, CLTC—Clathrin Light Chain C, CAV2—Caveolin 2, CTTN—Cortactin, Src—SRC Proto-Oncogene, PTK2—Protein Tyrosine Kinase 2, PXN—Paxilin, FN1—Fibronectin 1, ITGA5—Integrin Subunit Alpha 5, ILK—Integrin Linked Kinase, CDC42—Cell Division Cycle 42, WASL—WASP Like Actin Nucleation Promoting Factor, RAC1—Rac Family Small GTPase 1, WASF2—WASP Family Member 2, SGEF—Rho Guanine Nucleotide Exchange Factor 26, RhoG—Ras Homolog Family Member G, ELMO2—Engulfment And Cell Motility 2, DOCK180—Dedicator Of Cytokinesis 180, CRK—CRK Proto-Oncogene, MAD2L2—Mitotic Arrest Deficient 2 Like 2, RHOA—Ras Homolog Family Member A, ARPC4—Actin Related Protein 2/3 Complex Subunit 4, ACTG1—Actin Gamma 1, VCL—Vinculin.