Figure  7
Eno disrupts the BBB in vivo by inducing PBMEC apoptosis. A, Survival rates of SS2-infected mice; B Eno enhanced EB permeability into mouse brains; C SS2 enhanced EB permeability into mouse brains; D SS2 meningitic pig brains have higher expression of apoptosis-related molecules compared with that of healthy pig brains by immunohistochemical analysis; (*p < 0.05, **p < 0.01) (scale bar, 100 μm).