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Figure 4 | Veterinary Research

Figure 4

From: Activation of regulated cell death in the lung of piglets infected with virulent PRRSV-1 Lena strain occurs earlier and mediated by cleaved Caspase-8

Figure 4

Immunohistochemical expression of TUNEL, cCasp3, cCasp8 and cCasp9 in the lung along the experiment. Graph displays the number of TUNEL+ in the lung (cells/mm2) (A). Scatter dot plots show individual values from each animal and dashed lines indicate the median for each group and time points. Columns represent the median with range of total positive cells. Graph represents the number of cCasp3+ (B), cCasp8+ (C) cCasp9+ (D) in the lung (cells/mm2). Scatter dot plots show individual values from each animal and dashed lines indicate the median for each group and time point. Columns represent the median with range of PAMs, septal macrophages lymphocytes and neutrophils. One pig infected with 3249 strain at 6 dpi was considered an outlier (empty green triangle). Graph displays the AUC (median) for the frequency of cCasp3, cCasp8 and cCasp9 positive cells in 3249 E and Lena-infected F group.

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Veterinary Research

ISSN: 1297-9716