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Figure 3 | Veterinary Research

Figure 3

From: Activation of regulated cell death in the lung of piglets infected with virulent PRRSV-1 Lena strain occurs earlier and mediated by cleaved Caspase-8

Figure 3

Immunohistochemistry for TUNEL and cCasp3 in the lung. TUNEL expression in a representative 3249- A and Lena-infected pig B euthanised at 8 dpi (bar, 50 μm). Insets show in detail the immunolabelling of TUNEL in the nuclei and cytoplasm (bar, 20 μm). PAMs (black arrow), interstitial macrophages (black arrow-head) as well as TUNEL− neutrophils (red arrows). cCasp3 expression in a representative 3249- C and Lena-infected pig D euthanised at 13 dpi (bar, 50 μm). Insets show in detail the expression of cCasp3 in the nuclei and cytoplasm of PAMs (bar, 20 μm).

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