Diagnosis of tuberculosis in wildlife: a systematic review

Table 7 Details of immunological diagnosis in possum.

Assay test	N/E	n_Se + n_Sp	Antigens	Se (%)	Sp (%)	References
ELISA	N	29 + 100	M. bovis culture filtrate MBP70	45^a 21^a 28^b	96^a 98^a 99^b	[100]
RT	N	38 + 91	ESAT-6, CFP-10, MPB83	44.7	85.7	[109]

N/E: natural or experimental infection; n_Se: number of TB positive animals used for evaluation of Se; n_Sp: number of TB negative animals used for evaluation of Sp; Se: sensitivity; Sp: specificity; ELISA: enzyme linked immunosorbent assay; RT: lateral flow rapid test (name not mentioned- Chembio Diagnostic Systems, Inc., USA).
^a Se or Sp of ELISA where blocking antibody against MBP70 is not used.
^b Se or Sp of blocking ELISA where a monoclonal antibody against MPB70 is used.

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