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Table 7 Details of immunological diagnosis in possum.

From: Diagnosis of tuberculosis in wildlife: a systematic review

Assay test N/E nSe + nSp Antigens Se (%) Sp (%) References
ELISA N 29 + 100 M. bovis culture filtrate MBP70 45a
21a
28b
96a
98a
99b
[100]
RT N 38 + 91 ESAT-6, CFP-10, MPB83 44.7 85.7 [109]
  1. N/E: natural or experimental infection; nSe: number of TB positive animals used for evaluation of Se; nSp: number of TB negative animals used for evaluation of Sp; Se: sensitivity; Sp: specificity; ELISA: enzyme linked immunosorbent assay; RT: lateral flow rapid test (name not mentioned- Chembio Diagnostic Systems, Inc., USA).
  2. a Se or Sp of ELISA where blocking antibody against MBP70 is not used.
  3. b Se or Sp of blocking ELISA where a monoclonal antibody against MPB70 is used.
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