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Table 2 Protection against virulentB. suisinduced by LPS and metabolic mutants inoculated subcutaneously.

From: Development of attenuated live vaccine candidates against swine brucellosis in a non-zoonotic B. suis biovar 2 background

Vaccine Dose (CFU/mouse) Mean ± SD of log10 CFU in spleen of
Bs2WT Vaccine
Bs2ΔwadB 105 3.97 ± 0.37a,b 2.61 ± 0.97
Bs2Δppdk 105 3.65 ± 0.43a,b 2.39 ± 0.54
Bs2ΔppdkΔwadB 105 4.12 ± 1.09a,b 2.68 ± 1.17
Bs2ΔwbkF 108 3.33 ± 0.36a,b 2.45 ± 0.56
Bs2Δwzm 108 2.83 ± 1.88a,b 2.52 ± 1.50
Rev1 105 3.68 ± 0.78a 2.43 ± 0.56
BSS 6.69 ± 0.13  
  1. Statistical comparison (n = 5) of mean log10 Bs2WT CFU/spleen: ap < 0.001 vs. BSS (unvaccinated) and bp > 0.05 vs. Rev1.