Table 1 Description of vaccination protocols applied to pigs by treatment groups in the two separate studies.
From: Exploring heterologous prime-boost vaccination approaches to enhance influenza control in pigs
Study | Description | Group | Vaccination | Route | Challenge | Necropsy | |
|---|---|---|---|---|---|---|---|
Prime | Boost | ||||||
1 | Whole inactivated vaccine comparison groups | COM/COM | COM | COM | i.m/i.m | H1 and H3 IAV | 10 pigs |
AUT/AUT | AUT | AUT | i.m/i.m | H1 and H3 IAV | 10 pigs | ||
AUT/COM | AUT | COM | i.m/i.m | H1 and H3 IAV | 10 pigs | ||
COM/AUT | COM | AUT | i.m/i.m | H1 and H3 IAV | 10 pigs | ||
NO VAC/CHA | Saline | Saline | −/− | H1 and H3 IAV | 10 pigs | ||
|  | Negative control group | NO VAC/NO CHA | Saline | Saline | −/− | Saline solution | 6 pigsa |
2 | Live attenuated vaccine comparison groups | LAIV/COM | LAIV | COM | i.n/i.m | H1 and H3 IAV | 10 pigs |
LAIV/NONE | LAIV | None | i.n/- | H1 and H3 IAV | 10 pigs | ||