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Table 3 Severity of histological lesions in the lungs, liver, kidneys, spleen and central nervous tissue (CNS) during the respective weeks post-infection (pi) in rabbits (from 5 animals in respective weeks) experimentally orally infected withEncephalitozoon cuniculi.

From: Characterization of humoral and cell-mediated immunity in rabbits orally infected with Encephalitozoon cuniculi

Week pi

Lungs

Liver

Kidneys

Spleen

CNS

2

+++

+

+

++

+

4

++

++

++

++

++

6

+

++

+++

++

+

8

+

++

++

+

+

  1. Extensive histopathological changes throughout the tissue were defined as severe (+++); focal changes as moderate (++); and occasional areas of increased cellularity, or perivascular or periportal cuffing were determined as mild (+).