The potential of acetylsalicylic acid and vitamin E in modulating inflammatory cascades in chickens under lipopolysaccharide-induced inflammation

Table 1 Experimental design of the chicken experiment

Treatments	Vitamin E level	LPS challenge	Acetylsalicylic acid
Placebo	Basal	–	–
LPS	Basal	+	–
LPS + ASA	Basal	+	+
Placebo	Gradually increasing	–	–
LPS	Gradually increasing	+	–
LPS + ASA	Gradually increasing	+	+

LPS—birds at 32 days of age were intraperitoneally injected at a dose of 250 μg/kg of body weight with E. coli LPS; ASA—acetylsalicylic acid at a dose of 1 g/kg of diet; basal vitamin E (vE) level—80 mg/kg of diet; gradually increasing vE level—160 and 240 mg/kg of diet fed in the period 8–21 days and 22–35 days, respectively.

ISSN: 1297-9716