Skip to main content

Table 2 List of downregulated posterior intestine proteins of rainbow trout in response to Yersinia ruckeri strains

From: Modulation of posterior intestinal mucosal proteome in rainbow trout (Oncorhynchus mykiss) after Yersinia ruckeri infection

Accession Refseq

Protein name

Number of quantified peptides

Biological process

Intestine in response to Y. ruckeri strain

3 dpe (fold change)

9 dpe (fold change)

28 dpe (fold change)

NP_001117719.1

Apolipoprotein A-I-1

6

Lipid metabolism

Biotype 1

−1.3

−1.1

−1.6

Biotype 2

−2.2*

−1.2

−1.1

NP_001154920.1

Apolipoprotein A-II

4

Lipid metabolism

Biotype 1

−2.1*

−1.0

−1.7

Biotype 2

−4.0*

1.1

−1.3

XP_021447265.1

Apolipoprotein C-I

2

Lipid metabolism

Biotype 1

−1.7

1.1

−3.1*

Biotype 2

−4.6*

−1.3

−2.7

XP_021422847.1

Filamin-A

6

Actin filament binding

Biotype 1

−3.2*

−2.8

−1.5

Biotype 2

−10.4*

−2.8

−1.4

XP_021438757.1

Alpha-actinin-1

6

Actin filament binding

Biotype 1

−2.4*

−1.7

−1.2

Biotype 2

−6.3*

−1.9

1.3

XP_021474949.1

PDZ and LIM domain protein 3

2

Alpha-actinin binding

Biotype 1

−4.2*

−2.5*

−1.1

Biotype 2

−22.6*

−1.7

1.1

XP_021479779.1

Dihydropyrimidinase-related protein 3

6

Actin filament bundle assembly

Biotype 1

−2.4*

−1.7

−1.3

Biotype 2

−4.5*

−1.6

−1.1

XP_021449109.1

Tubulin alpha chain

3

Microtubule process

Biotype 1

−2.1*

1.2

−1.8

Biotype 2

−4.9*

−1.2

−1.6

XP_021451765.1

Tubulin polymerization-promoting protein

6

Microtubule binding

Biotype 1

−3.6*

−1.7

−1.3

Biotype 2

−7.0*

−1.5

−1.2

XP_021480500.1

DnaJ homolog subfamily C member 7

2

Chaperone binding

Biotype 1

−1.9

1.1

−1.2

Biotype 2

−3.2*

−1.4

−1.0

XP_021478259.1

Lysosome membrane protein 2

2

Chaperone activity

Biotype 1

−2.6*

1.1

−1.3

Biotype 2

−3.3*

−1.3

−1.3

NP_001117706.1

Heat shock 47 precursor

6

Stress response

Biotype 1

−3.7*

−1.4

−1.1

Biotype 2

−9.6*

−1.2

1.0

XP_021438340.1

Heat shock cognate 70 kDa protein-like

6

Chaperone activity

Biotype 1

−1.9

−1.1

−1.3

Biotype 2

−2.6*

−1.4

−1.1

XP_021441996.1

Programmed cell death protein 5

2

DNA binding

Biotype 1

−2.7*

1.2

−1.7

Biotype 2

−4.4*

−1.4

−2.6*

XP_021418468.1

Annexin A13

6

Calcium ion binding

Biotype 1

−2.0*

−1.6

−1.8

Biotype 2

−3.4*

−1.2

−1.1

XP_021416101.1

Protein S100 A13

2

Calcium binding

Biotype 1

−3.2*

−1.1

−1.5

Biotype 2

−6.6*

−1.3

−1.1

NP_001117701.1

M-calpain

6

Calcium ion binding

Biotype 1

−2.0*

−1.2

−1.0

Biotype 2

−4.0*

−1.4

1.0

NP_001117963.1

Calpain 2 catalytic subunit

5

Calcium ion binding

Biotype 1

−1.8

−1.1

−1.1

Biotype 2

−2.6*

−1.0

−1.0

XP_021419099.1

l-Lactate dehydrogenase

2

Carboxylic acid metabolic process

Biotype 1

−3.4*

−1.5

−1.8

Biotype 2

−7.4*

−1.7

1.3

XP_021452473.1

Glyceraldehyde-3-phosphate dehydrogenase

4

Glycolysis process

Biotype 1

−1.8

−1.2

−1.3

Biotype 2

−2.9*

−1.1

−1.1

XP_021447060.1

Pyruvate dehydrogenase E1

4

Glucose metabolic process

Biotype 1

−2.1*

1.2

1.0

Biotype 2

−1.7

1.1

−1.0

XP_021440913.1

Galectin-5-like isoform X2

2

Carbohydrate binding

Biotype 1

−2.3*

1.0

1.1

Biotype 2

−3.9*

1.4

−1.2

XP_021476056.1

Eukaryotic translation initiation factor 5A

5

Translation

Biotype 1

−1.4

1.1

−1.4

Biotype 2

−2.4*

−1.3

−1.6

XP_021467048.1

40S ribosomal protein S12

5

Translation

Biotype 1

−1.1

1.4

−1.2

Biotype 2

−2.2*

1.2

1.3

XP_021456583.1

40S ribosomal protein S29

3

Translation

Biotype 1

−3.4*

1.0

−1.2

Biotype 2

−2.9*

−1.0

−1.3

  1. Fold change was statistically analyzed in the posterior intestine of rainbow trout exposed to Y. ruckeri biotype 1 (CSF007-82) and biotype 2 (A7959-11) versus control posterior intestine of rainbow trout samples (n = 3 per time point).
  2. * Statistically significant difference according to both ANOVA and post hoc Tukey’s HSD with FDR-adjusted p-value < 0.05 and fold change < −2 or > +2. (Full table is presented in Additional file 4).