Figure 4From: HcTTR: a novel antagonist against goat interleukin 4 derived from the excretory and secretory products of Haemonchus contortusEffects of rHcGST, rHcTTR and rHcCab on the biological function of rIL4. A Cell proliferation of PBMCs was detected using CCK-8 by rHcTTR co-incubated with rIL4 in vitro. B PBMC proliferation was detected using CCK-8 by rHcGST co-incubated with rIL4 in vitro. C PBMC proliferation was detected using CCK-8 by rHcCab co-incubated with rIL4 in vitro. Data are presented as the mean ± SD from three independent experiments, with three technical replicates per group, ****P < 0.0001 and ns: non-significant vs the negative control group (the control-pET32a treated group) and a capped line designates two groups that differ significantly (*P < 0.05, **P < 0.01, ***P < 0.0001).Back to article page