Role of p53 in pseudorabies virus replication, pathogenicity, and host immune responses

Table 4 Differential expressed anti-viral genes in brains of PRV-infected p53 ^−/− and wild-type mice.

Gene ID	Gene name	Gene description	Foldchange^a (p53^−/− and wild-type)
20846	Stat1	Signal transducer and activator of transcription 1	−3.0
53817	Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	−14.8
230073	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	−5.6
20210	Saa3	Serum amyloid A 3	−44.0
110454	Ly6a	Lymphocyte antigen 6 complex locus A	−3.8
100041546	Ly6c2	Lymphocyte antigen 6 complex locus C2	−23.0
231655	Oasl1	2′-5′ oligoadenylate synthetase-like 1	−68.0
23962	Oasl2	2′-5′ oligoadenylate synthetase-like 2	−9.3
17857	Mx1	MX dynamin-like GTPase 1	−76.9
58185	Rsad2	Radical S-adenosyl methionine domain containing 2	−37.1

^a Fold activation represents the fold increase in the level of activation in p53^−/− mice compared with the level of activation in wild-type mice.

ISSN: 1297-9716