Figure 8From: Saccharomyces cerevisiae mannan induces sheep beta-defensin-1 expression via Dectin-2-Syk-p38 pathways in ovine ruminal epithelial cellsSchematic diagram of the regulation of SBD-1 expression by mannan. Mannan binds to Dectin-2 receptor, activates the MAPK and NF-kB signaling pathways, and subsequently stimulates SBD-1 expression in OREC.Back to article page