Low levels of classical BSE infectivity in rendered fat tissue

Table 1 Anamnestic data of the celiac and mesenteric ganglion complex used and results of the mouse bioassay done with rendered mesentery fat

	Animal ID	mpi	Results CMGC [8]		Results rendered fat
	Animal ID	mpi	Mouse-bioassay (Tgbov XV)	IHC	Mouse-bioassay (Tgbov XV)
Negative control	KT30	20	Not done	Negative	0/11 > 629 dpi
Preclinical	IT46	16	+ (2/12)	Negative	0/10 > 664 dpi
Preclinical	IT60	20	++ (7/14)	Negative	0/8 > 592 dpi
Late preclinical	IT61	32	++ (9/13)	+	0/7 > 633 dpi
Clinical	IT49	36	+++ (7/9)	+	1/6 586 dpi

mpi: months post-infection, CMGC: celiac and mesenteric ganglion complex, IHC: immunohistochemistry, + mild, ++ moderate, +++ severe infectivity respectively accumulation of PrP^Sc; the numbers in brackets shows the number of positive mice/inoculated mice, dpi: days post-infection.

ISSN: 1297-9716