Source
|
Recipient
|
Passage #
|
Survival perioda
|
n/n
bo
|
---|
Sh294 brain (CH1641-like Scrapie)
|
TgBoPrP
|
3
|
172 ± 4.5*
|
11/11
|
Cattle L-BSE brain
|
TgBoPrP
|
3
|
144 ± 4.8*
|
12/12
|
Cattle C-BSE brain
|
TgBoPrP
|
3
|
195 ± 4.6
|
14/14
|
Cattle H-BSE brain
|
TgBoPrP
|
3
|
220 ± 4.3
|
11/11
|
- aSurvival periods are shown as mean survival days ± standard deviation.
- bNumber of PrPres-positive mice out of the total number of challenged mice. All inoculated mice showed unique clinical signs of the disease (Sh294 and L-BSE, circling behavior; C-BSE, head twitching; H-BSE, constant chewing of the bedding).
- * P < 0.0001.