Table 3 The top proteins with the largest change in expression in response to ASFV infection (3 dpi)
Attenuated-control | ||||||||
|---|---|---|---|---|---|---|---|---|
ID SSP | ID | Gen name | Protein name | pI | Mw (kDa) | % coverage | Fold change | p value |
7226 | O15144 | ARPC2 | Actin-related protein 2/3 complex subunit 2 Homo sapiens | 6.84 | 34.4 | 45 | 13.1 | 0.0017 |
5435 | P50395 | GDI2 | Rab GDP dissociation inhibitor beta Sus scrofa | 6.31 | 50.70 | 49 | 12.4 | 0.0077 |
1427 | Q0QEN7 | ATP5B | ATP synthase subunit beta Sus scrofa | 4.99 | 47 | 58 | 10.7 | 0.0121 |
1133 | P20700 | LMNB1 | Lamin-B1 Homo sapiens | 5.11 | 66.40 | 14 | 8.5 | 0.0103 |
3625 | P11142 | HSP7C | Heat shock cognate 71 kDa protein Homo sapiens | 5.37 | 70.80 | 27 | 8.4 | 0.0052 |
8533 | Q6MZU6 | IGHM | IgG heavy chain Sus scrofa | 6.82 | 52.90 | 25 | 6.1 | 0.0247 |
8321 | B1ALA9 | PRPS1 | Phosphoribosyl pyrophosphate synthetase 1 Rattus norvegicus | 7.62 | 24.40 | 37 | 5.6 | 0.0003 |
2322 | P04899 | GNA12 | Guanine nucleotide-binding protein G(i) subunit alpha-2 Sus scrofa | 5.35 | 41.00 | 52 | 5.4 | 0.0122 |
2548 | P54920 | NAPA | Alpha-soluble NSF attachment protein Homo sapiens | 5.23 | 33.66 | 65 | 5.2 | 0.0021 |
6128 | Q8MJ14 | GPX1 | Glutathione peroxidase 1 Sus scrofa | 6.73 | 22.40 | 22 | 5.1 | 0.0013 |
2026 | O89052 | TUBA1B | Alpha-tubulin Mus musculus | 4.85 | 11 | 60 | − 34.8 | 0.0008 |
1021 | P08835 | ALB | Serum albumin Sus scrofa | 6.08 | 69.70 | 18 | − 24.3 | 0.0000 |
2131 | P84856 | ACTB | Actin.cytoplasmic 1 Cercopithecus pygerythrus | 5.55 | 40.4 | 21 | − 18.1 | 0.0104 |
4017 | P61981 | YWHAG | 14-3-3 protein gamma Homo sapiens | 4.8 | 28.30 | 47 | − 17.3 | 0.0210 |
3017 | P63104 | YWHAZ | 14-3-3 protein zeta/delta Homo sapiens | 4.73 | 27.90 | 46 | − 16.5 | 0.0001 |
4135 | P00829 | ATPB | ATP synthase subunit beta.mitochondrial Bos taurus | 5.15 | 56.2 | 29 | − 11.2 | 0.0043 |
4013 | P31946 | YWHAB | 14-3-3 protein beta/alpha Homo sapiens | 4.76 | 28.20 | 63 | − 8.9 | 0.0000 |
4234 | Q9MYP6 | HSD17B14 | 17-beta-hydroxysteroid dehydrogenase 14 Bos taurus | 6.19 | 28.40 | 7 | − 5.9 | 0.0070 |
8148 | P09571 | TF | Serotransferrin Sus scrofa | 6.93 | 76.90 | 3 | − 4.9 | 0.0015 |
1018 | Q2HJ57 | COTL1 | Coactosin-like protein Bos taurus | 5.1 | 16.00 | 36 | − 4.6 | 0.0199 |
Virulent-control | ||||||||
|---|---|---|---|---|---|---|---|---|
ID SSP | ID | Gen name | Protein name | pI | Mw (kDa) | % coverage | Fold change | p value |
5435 | P50395 | GDI2 | Rab GDP dissociation inhibitor beta Sus scrofa | 6.31 | 50.70 | 49 | 16.3 | 0.0108 |
5142 | P19133 | FTL | Ferritin light chain Sus scrofa | 5.8 | 28.70 | 32 | 11.6 | 0.0001 |
7226 | O15144 | ARPC2 | Actin-related protein 2/3 complex subunit 2 Homo sapiens | 6.84 | 34.4 | 45 | 8.7 | 0.0036 |
1427 | Q0QEN7 | ATP5B | ATP synthase subunit beta Sus scrofa | 4.99 | 47 | 58 | 8.6 | 0.0000 |
1133 | P20700 | LMNB1 | Lamin-B1 Homo sapiens | 5.11 | 66.40 | 14 | 6.3 | 0.0004 |
7137 | P60900 | PSMA6 | Proteasome subunit alpha type-6 Homo sapiens | 6.34 | 27.30 | 26 | 5.1 | 0.0004 |
1640 | P01009 | SERPINA1 | Alpha-1-antitrypsin Sus scrofa | 5.54 | 47.4 | 11 | 4.2 | 0.0029 |
6332 | P56471 | IDH3A | Isocitratedehydrogenase [NAD] subunitalpha Sus scrofa | 6.72 | 40.10 | 50 | 4.0 | 0.0003 |
1130 | P52552 | PRDX2 | Peroxiredoxin-2 Sus scrofa | 4.66 | 14.10 | 36 | 3.6 | 0.0000 |
1224 | P08758 | ANXA5 | Annexin A5 Homo sapiens | 4.94 | 35.8 | 59 | 3.2 | 0.0034 |
3123 | P84856 | ACTB | Actin.cytoplasmic 1 Cercopithecus pygerythrus | 5.55 | 40.4 | 29 | − 35.6 | 0.0082 |
4017 | P61981 | YWHAG | 14-3-3 protein gamma Homo sapiens | 4.8 | 28.30 | 47 | − 19.8 | 0.0190 |
1021 | P08835 | ALB | Serumalbumin Sus scrofa | 6.08 | 69.70 | 18 | − 12.7 | 0.0000 |
2026 | O89052 | TUBA1B | Alpha-tubulin Mus musculus | 4.85 | 11 | 60 | − 11.9 | 0.0001 |
4013 | P31946 | YWHAB | 14-3-3 protein beta/alpha Homo sapiens | 4.76 | 28.20 | 63 | − 11.1 | 0.0000 |
1331 | Q9N0Y9 | TMOD3 | Tropomodulin 3 Sus scrofa | 4.98 | 39.70 | 21 | − 10.5 | 0.0051 |
4234 | Q9MYP6 | HSD17B14 | 17-beta-hydroxysteroid dehydrogenase 14 Bos taurus | 6.19 | 28.40 | 7 | − 9.8 | 0.0062 |
3017 | P63104 | YWHAZ | 14-3-3 protein zeta/delta Homo sapiens | 4.73 | 27.90 | 46 | − 7.3 | 0.0000 |
515 | P13489 | RNH1 | Ribonuclease inhibitor Sus scrofa | 4.76 | 50.70 | 64 | − 5.7 | 0.0162 |
1018 | Q2HJ57 | COTL1 | Coactosin-like protein Bos taurus | 5.1 | 16.00 | 36 | − 4.6 | 0.0160 |