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Table 3 The top proteins with the largest change in expression in response to ASFV infection (3 dpi)

From: Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains

  Attenuated-control
ID SSP ID Gen name Protein name pI Mw (kDa) % coverage Fold change p value
7226 O15144 ARPC2 Actin-related protein 2/3 complex subunit 2 Homo sapiens 6.84 34.4 45 13.1 0.0017
5435 P50395 GDI2 Rab GDP dissociation inhibitor beta Sus scrofa 6.31 50.70 49 12.4 0.0077
1427 Q0QEN7 ATP5B ATP synthase subunit beta Sus scrofa 4.99 47 58 10.7 0.0121
1133 P20700 LMNB1 Lamin-B1 Homo sapiens 5.11 66.40 14 8.5 0.0103
3625 P11142 HSP7C Heat shock cognate 71 kDa protein Homo sapiens 5.37 70.80 27 8.4 0.0052
8533 Q6MZU6 IGHM IgG heavy chain Sus scrofa 6.82 52.90 25 6.1 0.0247
8321 B1ALA9 PRPS1 Phosphoribosyl pyrophosphate synthetase 1 Rattus norvegicus 7.62 24.40 37 5.6 0.0003
2322 P04899 GNA12 Guanine nucleotide-binding protein G(i) subunit alpha-2 Sus scrofa 5.35 41.00 52 5.4 0.0122
2548 P54920 NAPA Alpha-soluble NSF attachment protein Homo sapiens 5.23 33.66 65 5.2 0.0021
6128 Q8MJ14 GPX1 Glutathione peroxidase 1 Sus scrofa 6.73 22.40 22 5.1 0.0013
2026 O89052 TUBA1B Alpha-tubulin Mus musculus 4.85 11 60 − 34.8 0.0008
1021 P08835 ALB Serum albumin Sus scrofa 6.08 69.70 18 − 24.3 0.0000
2131 P84856 ACTB Actin.cytoplasmic 1 Cercopithecus pygerythrus 5.55 40.4 21 − 18.1 0.0104
4017 P61981 YWHAG 14-3-3 protein gamma Homo sapiens 4.8 28.30 47 − 17.3 0.0210
3017 P63104 YWHAZ 14-3-3 protein zeta/delta Homo sapiens 4.73 27.90 46 − 16.5 0.0001
4135 P00829 ATPB ATP synthase subunit beta.mitochondrial Bos taurus 5.15 56.2 29 − 11.2 0.0043
4013 P31946 YWHAB 14-3-3 protein beta/alpha Homo sapiens 4.76 28.20 63 − 8.9 0.0000
4234 Q9MYP6 HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 Bos taurus 6.19 28.40 7 − 5.9 0.0070
8148 P09571 TF Serotransferrin Sus scrofa 6.93 76.90 3 − 4.9 0.0015
1018 Q2HJ57 COTL1 Coactosin-like protein Bos taurus 5.1 16.00 36 − 4.6 0.0199
  Virulent-control
ID SSP ID Gen name Protein name pI Mw (kDa) % coverage Fold change p value
5435 P50395 GDI2 Rab GDP dissociation inhibitor beta Sus scrofa 6.31 50.70 49 16.3 0.0108
5142 P19133 FTL Ferritin light chain Sus scrofa 5.8 28.70 32 11.6 0.0001
7226 O15144 ARPC2 Actin-related protein 2/3 complex subunit 2 Homo sapiens 6.84 34.4 45 8.7 0.0036
1427 Q0QEN7 ATP5B ATP synthase subunit beta Sus scrofa 4.99 47 58 8.6 0.0000
1133 P20700 LMNB1 Lamin-B1 Homo sapiens 5.11 66.40 14 6.3 0.0004
7137 P60900 PSMA6 Proteasome subunit alpha type-6 Homo sapiens 6.34 27.30 26 5.1 0.0004
1640 P01009 SERPINA1 Alpha-1-antitrypsin Sus scrofa 5.54 47.4 11 4.2 0.0029
6332 P56471 IDH3A Isocitratedehydrogenase [NAD] subunitalpha Sus scrofa 6.72 40.10 50 4.0 0.0003
1130 P52552 PRDX2 Peroxiredoxin-2 Sus scrofa 4.66 14.10 36 3.6 0.0000
1224 P08758 ANXA5 Annexin A5 Homo sapiens 4.94 35.8 59 3.2 0.0034
3123 P84856 ACTB Actin.cytoplasmic 1 Cercopithecus pygerythrus 5.55 40.4 29 − 35.6 0.0082
4017 P61981 YWHAG 14-3-3 protein gamma Homo sapiens 4.8 28.30 47 − 19.8 0.0190
1021 P08835 ALB Serumalbumin Sus scrofa 6.08 69.70 18 − 12.7 0.0000
2026 O89052 TUBA1B Alpha-tubulin Mus musculus 4.85 11 60 − 11.9 0.0001
4013 P31946 YWHAB 14-3-3 protein beta/alpha Homo sapiens 4.76 28.20 63 − 11.1 0.0000
1331 Q9N0Y9 TMOD3 Tropomodulin 3 Sus scrofa 4.98 39.70 21 − 10.5 0.0051
4234 Q9MYP6 HSD17B14 17-beta-hydroxysteroid dehydrogenase 14 Bos taurus 6.19 28.40 7 − 9.8 0.0062
3017 P63104 YWHAZ 14-3-3 protein zeta/delta Homo sapiens 4.73 27.90 46 − 7.3 0.0000
515 P13489 RNH1 Ribonuclease inhibitor Sus scrofa 4.76 50.70 64 − 5.7 0.0162
1018 Q2HJ57 COTL1 Coactosin-like protein Bos taurus 5.1 16.00 36 − 4.6 0.0160