Bird type (age)
|
Pathotype
|
Day post-challenge
|
No. with virus detected/total (titer as log10 EID50/g)d
|
---|
Lung
|
Spleen
|
Heart
|
Brain
|
Muscle
|
Reproductive tracte
|
---|
Broiler breeders (36w)a
|
LP
|
3
|
0/3
|
0/3
|
0/3
|
0/3
|
0/3
|
0/3
|
SPF White Leghorn (4w)b
|
LP
|
3
|
0/2
|
0/2
|
0/2
|
0/2
|
0/2
|
nd
|
SPF White Leghorn (4w)c
|
HP
|
2
|
2/2 (7.2 ± 0.3)
|
2/2 (7.3 ± 0.2)
|
2/2 (8.3 ± 0.3)
|
2/2 (7.0 ± 0.6)
|
2/2 (7.5 ± 0.4)
|
nd
|
- Virus detection by qRRT-PCR.
- nd: not determined.
- aTissues from 3 broiler breeders necropsied at 3 dpc. The threshold of detection in tissues was 1.9 log10 EID50/g for H7N9 LPAI virus.
- bTissues from 2 SPF layer birds necropsied at 3 dpc. The threshold of detection in tissues was 1.9 log10 EID50/g for H7N9 LPAI virus.
- cTissues from 2 SPF layer birds necropsied at 2 dpc. The threshold of detection in tissues was 2.5 log10 EID50/g for H7N9 HPAI virus.
- dMean titer ± SD.
- eAll sections of the reproductive tract were tested: ovary, infundibulum, magnum, isthmus, and shell gland.