|
Bird type (age)
|
Challenge virus
|
Dose (log10)
|
Inoculated infected/totala
|
BID50 (log10)
|
Inoculated dead/total (MDTb)
|
BLD50 (log10)
|
Contact-exposed infected/totalc
|
|---|
|
Broiler breeders (36w)
|
H7N9 LPAI
|
2
|
0/5
|
5.6
|
0/5
|
>6
|
nd
|
| |
4
|
2/5
| |
0/5
| |
nd
|
| |
6
|
2/5
| |
0/5
| |
nd
|
|
–
|
sham
|
0/5
|
–
|
0/5
|
–
|
–
|
|
SPF White Leghorn (4w)
|
H7N9 LPAI
|
2
|
0/5
|
4.3
|
0/5
|
>6
|
0/3
|
| |
4
|
2/5
| |
0/5
| |
0/3
|
| |
6
|
5/5
| |
0/5
| |
0/3
|
|
SPF White Leghorn (4w)
|
H7N9 HPAI
|
2
|
3/5
|
<2
|
3/5 (2.3)
|
<2
|
0/3
|
| |
4
|
5/5
| |
5/5 (≤2.4)
| |
0/3
|
| |
6
|
5/5
| |
5/5 (2.2)
| |
1/3 (dead)
|
|
–
|
sham
|
0/5
|
–
|
0/5
|
–
|
–
|
- BID50: mean bird infectious dose, BLD50: mean bird lethal dose, MDT: mean death time in days, nd: not determined.
- aBirds were considered infected if they shed virus and/or were positive for antibodies at 14 dpc.
- b#dead birds × dpc/total dead birds.
- cContact-exposed birds were considered infected if they died, shed virus, and/or were positive for antibodies at 14 dpc.
